BPS2024 Full Program & Abstracts

1468-Pos Travel Award Winner CONNEXIN HEMICHANNELS FUNCTION AS MOLECULE TRANSPORTERS INDEPENDENTLY OF ION CONDUCTION. Pablo S. Gaete , Deepak Kumar, Cynthia I. Fernandez, Juan M. Valdez Capuccino, Yu Liu, Andrew L. Har ris, Yun Lyna Luo, Jorge E. Contreras 1469-Pos Board B422 HUMAN CX50 ISOLEUCINE177 IS CRITICAL FOR HETEROTYPIC DOCKING AND FORMATION OF FUNCTIONAL GAP JUNCTION CHANNELS WITH CX43. Robert S. Wong, Honghong Chen, Yi X. Li, Jessica L. Esseltine, Peter B. Stathopulos, Donglin Bai 1470-Pos Board B423 FLUOROMETRIC ANALYSIS OF THE INTERACTIONS BETWEEN VOLTAGE SENSING PHOSPHATASE (VSP) AND PI(4,5)P 2 . Natsuki Mizutani , Yasushi Board B424 PERMEATION OF CO2 THROUGH THE CENTRAL PORE OF HUMAN AQP5. Eric Shinn , Thomas Kowatz, Ardeschir Vahedi-Faridi, Walter F. Boron, Emad Tajkhorshid 1472-Pos Board B425 DETECTION OF CITRULLINE MODIFICATION IN HISTONE PEPTIDES USING BIOLOGICAL NANOPORE. Priyanka Jain , Tobias Ensslen, Jan C. Behrends 1473-Pos Board B426 Travel Award Winner IMPACT OF THE AQP5 H173D MUTATION ON H 2 O AND CO 2 PERMEABIL ITY: PHYSIOLOGY AND MD STUDIES. Popular Pandey , Nisha Bhattarai, Deng-Ke Wang, Thomas Kowatz, Eric Shinn, Emad Tajkhorshid, Ardeschir Vahedi-Faridi, Walter F. Boron 1474-Pos Board B427 USING ALPHAFOLD2 AND NMR SPECTROSCOPY TO TEST FAMILY-WIDE TMC-CIB INTERACTIONS. Wei-Hsiang Weng, Jonathan S. Montgomery, Shounak Mukherjee, Yaw Agyemang, Travis Harrison-Rawn, Qurat Ashraf, Mark P. Foster, Marcos M. Sotomayor 1475-Pos Board B428 KINETICS AND PERMEATION PROPERTIES OF MAMMALIAN PIEZO CHANNELS. Tharaka D. Wijerathne , Jerome J. Lacroix 1476-Pos Board B429 Travel Award Winner INNATE PHOSPHOLIPID SCRAMBLASE CAPABILITY IN THE TMEM16 AND OSCA/TMEM63 FAMILIES. Augustus J. Lowry , Pengfei Liang, Yang Zhang, Yui Chun Serena Wan, Huanghe Yang 1477-Pos Board B430 Travel Award Winner FUNCTIONAL INSIGHTS INTO THE ACTIVITY OF CA 2+ CHANNELS RESPON SIBLE FOR THE GENERATION OF ACTION POTENTIALS IN THE MACRO PHYTE NITELLOPSIS OBTUSA . Vilmantas Pupkis , Indre Lapeikaite, Vilma Kisnieriene Smooth Muscle and Cardiac Muscle Mechanics and Structure I (Boards B431 - B448) 1478-Pos Board B431 ESTIMATING THE EFFECT OF DANICAMTIV ON HUMAN CARDIAC FUNC TION. Srboljub M. Mijailovich , Momcilo Prodanovic, Vanja Cvetkovic, Andjela Grujic, Michael Regnier, Farid Moussavi-Harami 1479-Pos Board B432 DECIPHERING THE MOLECULAR MECHANISM OF THE SMALL MOLECULE MYOTROPE DANICAMTIV. Brent Scott , Michael J. Greenberg 1480-Pos Board B433 THE EFFECT OF SMALL MOLECULE MYOSIN INHIBITORS ON ATP CYCLING IN PORCINE CARDIAC MUSCLE USING STOPPED-FLOW SPECTROSCOPY AND IN VITRO MOTILITY. Max Mahoney-Schaefer , Kristina B. Kooiker, Saffie Mohran, Galina V. Flint, Michael Regnier, Farid Moussavi-Harami Board B421 Okamura 1471-Pos

1481-Pos Board B434 MECHANISMS OF MYOSIN, MYOFIBRIL AND CARDIOMYOCYTE DYS FUNCTION WITH THE MYH7 R403Q MUTATION IN PORCINE VENTRICLE MUSCLE. Saffie Mohran, Sonette Steczina, Kristina B. Kooiker, Timothy McMillen, Christian Mandrycky, Matthew C. Childers, Kerry Y. Kao, Jingyuan Yu, Siyao Jiang, Thomas C. Irving, Jing Zhao, Michael A. Geeves, Neil M. Kad, Weikang Ma, Michael Regnier 1482-Pos Board B435 Travel Award Winner A MOLECULAR DYNAMICS INVESTIGATION OF THE DYSFUNCTION OF THE DILATED CARDIOMYOPATHY-ASSOCIATED MYH7 MUTATION R369Q. Aditi M. Prabhala , Matthew C. Childers, Kerry Y. Kao, Michael Regnier 1483-Pos Board B436 A MOLECULAR-SCALE INVESTIGATION OF THE MECHANISMS OF CON TRACTILE DYSFUNCTION FOR THE HYPERTROPHIC CARDIOMYOPATHY MYH7 G256E MUTATION. Kerry Y. Kao , Matthew C. Childers, Saffie Mohran, Michael Regnier 1484-Pos Board B437 MODULATION OF CARDIAC TWITCHES BY TEMPERATURE AND STIMU LATION FREQUENCY. Momcilo Prodanovic , Corrado Poggesi, Michael Regnier, Thomas C. Irving, Michael A. Geeves, Srboljub M. Mijailovich 1485-Pos Board B438 TEMPERATURE-DEPENDENT FRET REVEALS UNCOUPLING OF THE SUPER-RELAXED STATE AND INTERACTING HEADS MOTIF. Jinghua Ge, Kevin E. Namitz, Skylar M.L. Bodt, Ianna S. Debrunner, Sivaraj Sivaramak rishnan, Neela Yennawar, Christopher M. Yengo 1486-Pos Board B439 ISOLATING THE CELLULAR AND EXTRACELLULAR CONTRIBUTIONS TO DIASTOLIC MECHANICS IN A RAT MODEL OF HFPEF. Alexa R. Price , Shaina L. Weingart, Emmaleigh N. Hancock, Bradley M. Palmer, Mat thew A. Caporizzo 1487-Pos Board B440 HALF-SARCOMERES RELAX WITH A BIPHASIC TIME-COURSE IN SPATIAL LY-EXPLICIT SIMULATIONS WITH SERIES COMPLIANCE. Caterina Squarci , Kenneth S. Campbell 1488-Pos Board B441 A MISSENSE VARIANT IN THE Z-DISC PROTEIN ΑACTININ 2: EVIDENCE FOR A SARCOMERE PROTEIN AT THE NEXUS OF THICK AND THIN FILA MENT REGULATION. Michelle C. Rodriguez Garcia , Jeffrey Schmeckpep er, Maicon Landim-Vieira, Isabella Leite Coscarella, Xuan Fang, Weikang Ma, Payton A. Spran, Aida Rahimi Kahmini, Moore B. Shoemaker, James B. Atkinson, Peter Kekenes-Huskey, Thomas Irving, Prescott B. Chase, Björn C. Knollmann, J. Renato Pinto 1489-Pos Board B442 COLCHICINE INCREASES MYOCARDIAL WORK OUTPUT IN A RAT MODEL OF HFPEF. Emmaleigh N. Hancock , Alexa R. Price, Shaina L. Weingart, Raihan Kabir, Bradley M. Palmer, Matthew A. Caporizzo 1490-Pos Board B443 ANNOTATING THE X-RAY DIFFRACTION PATTERN OF VERTEBRATE STRIATED MUSCLE. Natalia A. Koubassova, Debabrata Dutta, Andrey K. Tsaturyan, Raul Padron, Roger Craig 1491-Pos Board B444 EFFECTS OF CMYBP-C PHOSPHORYLATION ON RELAXATION RATES IN MYOFIBRILS. Alexey V. Dvornikov 1492-Pos Board B445 INTRAMOLECULAR CROSSLINKS IN TITIN ADVANCED GLYCATION END PRODUCTS STIFFEN CARDIOMYOCYTES. Agata Bak , Andra C. Dumitru, Diana Velázquez-Carreras, Maria Rosaria Pricolo, Inés Martínez-Martín, Francisco M. Espinosa, Elías Herrero Galán, Enrique Calvo, Ricardo García, Jesús Vázquez, Inês Falcão-Pires, Miquel Adrover, Jorge Alegre Cebollada

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