BPS2024 Full Program & Abstracts

2140-Pos Board B289 COMPUTATIONAL MODELING IDENTIFIES INCREASED BACKGROUND CA 2+ INFLUX AS A POTENTIAL PROMOTER OF ARRHYTHMOGENIC CA 2+ INSTABILITY IN ATRIAL FIBRILLATION. Haibo Ni , Najme Khorasani, Yixuan Wu, Stefano Morotti, Dobromir Dobrev, Eleonora Grandi 2141-Pos Board B290 SEX-SPECIFIC MECHANISMS OF ATRIAL ELECTROPHYSIOLOGY AND AR RHYTHMIA SUSCEPTIBILITY IN THE INTACT RABBIT HEART. Charlotte E.R. Smith , Amanda M. Guevara, Lianguo Wang, Eleonora Grandi, Crystal M. Board B291 IP3-RECEPTOR EXPRESSION AND CO-LOCALIZATION WITH HCN4 IN SI NOATRIAL MYOCYTES. Avery A. Langley , Colin H. Peters, Daniel Enders, Cathy Proenza 2143-Pos Board B292 STRUCTURAL AND ELECTROPHYSIOLOGICAL EFFECTS OF HISTONES IN ISOLATED VENTRICULAR MYOCYTES. Moza M. Al-Owais , Derek S. Steele 2144-Pos Board B293 STOCHASTIC RESONANCE ENSURES FAIL-SAFE OPERATION OF CARDIAC PACEMAKER AT LOW RATES. Isabella K. He , Alexander V. Maltsev, Anna V. Maltsev, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev 2145-Pos Board B294 CARDIAC SPECIFIC OVEREXPRESSION OF ADENYLYL CYCLASE 8 REPRO GRAMS THE MOUSE SINOATRIAL NODE TRANSCRIPTOME. Jia-Hua Qu , Kirill V. Tarasov, Khalid Chakir, Edward G. Lakatta 2146-Pos Board B295 SPHINGOMYELINASE-INDUCED ROS PRODUCTION SUPPRESSES CAR DIAC PERFORMANCE. Roman Y. Medvedev , Daniel G.P. Turner, Brock W. Thompson, Alexey V. Glukhov 2147-Pos Board B296 CHANGES IN CARDIAC MATURATION FROM BIRTH THROUGH ADOLES CENCE: EFFECTS ON CARDIAC ELECTROPHYSIOLOGY. Jacob A. Miller , Shatha Salameh, Devon Guerrelli, Nicolae Moise, Nikki G. Posnack, Seth H. Weinberg 2148-Pos Board B297 PHOSPHOLAMBAN INHIBITS THE CARDIAC CALCIUM PUMP BY INTER RUPTING AN ALLOSTERIC ACTIVATION PATHWAY. Sean R. Cleary , Jaro slava Seflova, Ellen E. Cho, Konark Bisht, Himanshu Khandelia, L. Michel Espinoza-Fonseca, Seth L. Robia 2149-Pos Board B298 DISTINCT MICRODOMAIN OF SODIUM CHANNEL COMPLEXES WITH INTRACELLULAR FIBROBLAST GROWTH FACTORS IN CARDIOMYO CYTES. Paweorn Angsutararux , Bence Hegyi, Donald M. Bers 2150-Pos Board B299 EFFECTS OF CARBON MONOXIDE ON ACTION POTENTIALS IN ICELL 2 HIPSC CARDIOMYOCYTES. Moza M. Al-Owais, Arun V. Holden, Derek S. Steele 2151-Pos Board B300 Travel Award Winner ELECTROPHYSIOLOGICAL PROFILE OF MURINE AND HUMAN WILD TYPE AND DYSTROPHIC MYOFIBER PRECURSORS: FROM MANUAL TO AUTOMATED PATCH-CLAMP. Alessandro Giovanni Cerchiara , Ornella Cappellari, Niels Fertig, Nadine Becker, Alison Obergrussberger, Michela De Bellis, Dominic J. Wells, Vincent Mouly, Jean-Francois Rolland, Paola Imbrici, Annamaria De Luca 2152-Pos Board B301 THE DISTRIBUTION OF I CA.L MAGNITUDES IN ICELL2 CARDIOMYO CYTES. Vincent Jaques , S Akkaya, Moza M. Al-Owais, Derek S. Steele, Arun V. Holden Ripplinger 2142-Pos

2153-Pos Board B302 A NOVEL BIOREACTOR TO APPLY DYNAMIC LOAD TO NEONATAL LAMB LIVING MYOCARDIAL SLICES AND HUMAN ENGINEERED HEART TISSUE FOR THE STUDY OF REGENERATIVE PROPERTIES OF THE HEART. Barrett Board B303 SPATIOTEMPORAL ORGANIZATION AND REGULATION OF CAV1.2 IN ADULT MOUSE CARDIOMYOCYTES. Sergej Borowik , Zunaira Shuja, Nourdine Chakouri, Lucile Fossier, Manu Ben-Johny, Lin Yang, Steven O. Marx, Henry M. Colecraft 2155-Pos Board B304 CONTRACTILE PHENOTYPES OF ENGINEERED HEART TISSUES DERIVED FROM HYPERTROPHIC CARDIOMYOPATHY PATIENTS LACKING SARCO MERIC MUTATIONS. Yusuf S. Rasheed , Samuel Young, Saiti S. Halder, Xia Li, John Stendahl, Stuart G. Campbell 2156-Pos Board B305 DLG1 GENE EXPRESSION AND SEXUAL DIMORPHISM IN REGULATION OF HEART RATE AND ITS VARIABILITY IN A MURINE MODEL. Danyal Raza , Shoaib Siddiqui, Ivan Kalla, Roberto Mondragon, Oluwadamola Olaiya, Erika Anderson, Lori L. Isom, Omer Berenfeld, Justus M. Anumonwo 2157-Pos Board B306 TRANSLATING ELECTROCARDIOGRAM FEATURES ACROSS SEXES. Roshni Shetty , Stefano Morotti, Vladimir Sobota, Jason D. Bayer, Haibo Ni, Eleonora Grandi 2158-Pos Board B307 PP2A AND OBESITY-LINKED ATRIAL REMODELING. Andrea Corbin , Kelly A. Aromolaran, Molly S. O’Connor, Ademuyiwa S. Aromolaran 2159-Pos Board B308 INTERPLAY BETWEEN BETA-ADRENERGIC SIGNALING AND ION CHAN NEL EXPRESSION ELUCIDATE REMODELING AND ARRHYTHMIA RISK IN A SIMULATED POPULATION OF HUMAN VENTRICULAR MYOCYTES WITH HEART FAILURE. Jacob A. Miller, Nicolae Moise, Seth H. Weinberg 2160-Pos Board B309 IN SILICO INVESTIGATION OF SEX-SPECIFIC ATRIAL ELECTROPHYSI OLOGIC MECHANISMS AND ARRHYTHMIA VULNERABILITY. Nathaniel T. Herrera , Haibo Ni, Charlotte Smith, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi 2161-Pos Board B310 CALMODULIN MUTATION D132E IN DIFFERENT GENES CAUSES DIFFER ENT ARRHYTHMIA PHENOTYPES. Roland Veress , Andriy E. Belevych, Radmila Terentyeva, Fruzsina Perger, Matthew Gorr, Vladimir Bogdanov, Anastasiia Pokrass, Shane D. Walton, Amer Charif, Jonathan P. Davis, Sandor Gyorke, Shanna Hamilton, Dmitry A. Terentyev TRP Channels (Boards B311 - B343) 2162-Pos Board B311 THE IMPLICATIONS OF A TEMPERATURE-DEPENDENT HEAT CAPACITY DC P (T) ON TEMPERATURE-DEPENDENT GATING IN THER MOTRPS. Frank Yeh , Andres Jara-Oseguera, Richard W. Aldrich 2163-Pos Board B312 FUNCTIONAL CONSERVATION OF THE COOLING AGENT BINDING SITE IN THE TRANSIENT RECEPTOR POTENTIAL MELASTATIN SUBFAMILY. Kate Huffer , Kenton Swartz 2164-Pos Board B313 VISUALIZATION OF TRPML1-CONTAINING LYSOSOMES IN SITU . Aria E. Garrett , Elaine M. Mihelc, Bridget McVeigh, Vera Moiseenkova-Bell Downing 2154-Pos

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