BPS2024 Full Program & Abstracts

Platform Calcium Handling and Electrophysiology II 1:00 pm - 3:00 pm, Room 103AB

Platform DNA Structure and Dynamics 1:00 pm - 3:00 pm, Room 113AB

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Co-Chairs Robyn Rebbeck, University of Minnesota, USA Dmitry Terentyev, The Ohio State University, USA 2549-Plat 1:00 pm MODULATING MITOCHONDRIAL PHOSPHATE TRANSPORT SHAPES IN TRACELLULAR CA SIGNALING TO IMPACT ARRHYTHMOGENESIS. Arpita Deb, Bjorn C. Knollmann, Bin Liu 2550-Plat 1:15 pm CALCIUM CHANNEL TARGETED MODULATORS IDENTIFIED BY FRET BASED HIGH-THROUGHPUT SCREENING. Jonathan C. Solberg, Benjamin D. Van Setters, Marzena Brinkmann, Andrew R. Thompson, Courtney C. Aldrich, Donald M. Bers, David D. Thomas, Robyn T. Rebbeck 2551-Plat 1:30 pm QUANTITATIVE INVESTIGATION OF THE MECHANISMS OF VENTRICULAR MYOCYTE DYSFUNCTION IN A MURINE MODEL OF HEART FAILURE WITH PRESERVED EJECTION FRACTION. Edith Jones, Bence Hegyi, Donald M. Bers, Stefano Morotti 2552-Plat 1:45 pm HETEROGENEOUS SIGNALS AND SOFT-GEOMETRIC NETWORK STRUC TURE IN THE MOUSE AV NODE. Anna V. Maltsev , Yasir Barlas, Adina T. Hazan, Rui Zhang, Joshua I. Goldhaber 2553-Plat 2:00 pm ER STRESS CONTRIBUTES TO CARDIAC ARRHYTHMIA IN CATECHOL AMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA. Roland Ver ess, Radmila Terentyeva, Fruzsina Perger, Andriy E. Belevych, Dmitry A. Terentyev, Shanna Hamilton 2554-Plat 2:15 pm SEX DIFFERENCES IN CELLULAR NA + - CA 2+ -HANDLING PROPERTIES IN RABBIT ATRIAL CARDIOMYOCYTES. András Horváth , Lucilla O.C. Giammarino, Nicolò Alerni, Miriam Barbieri, Julien Louradour, Saranda Nimani, Lluis Matas, Katja E. Odening 2555-Plat 2:30 pm CALMODULIN MUTATION D132E IN DIFFERENT GENES CAUSES DIFFER ENT ARRHYTHMIA PHENOTYPES. Roland Veress , Andriy E. Belevych, Radmila Terentyeva, Fruzsina Perger, Matthew Gorr, Vladimir Bogdanov, Anastasiia Pokrass, Shane D. Walton, Amer Charif, Jonathan P. Davis, Sandor Gyorke, Shanna Hamilton, Dmitry A. Terentyev 2556-FlashTalk 2:45 pm TRANSLATING ELECTROCARDIOGRAM FEATURES ACROSS SEXES. Roshni Shetty , Stefano Morotti, Vladimir Sobota, Jason D. Bayer, Haibo Ni, 2:50 pm DISTURBED CALCIUM HANDLING IN THE HEART OF THE COLLAGEN VI KNOCKOUT RAT. David J. Crossman 2558-FlashTalk 2:55 pm CANCELED LIFE-LONG CREATINE DEFICIENCY LEADS TO ADAPTATIONS IN CALCIUM HANDLING BUT NOT HEART FAILURE. Jelena Branovets , Martin Laas maa, Jekaterina Stolova, Xin Shen, Triinu Rätsepso, Mihkel Jaan Balodis, Cärolin Grahv, Eliise Hendrikson, William Edward Louch, Rikke Birkedal, Marko Vendelin Eleonora Grandi 2557-FlashTalk

Co-Chairs Jan Huertas Martin, Cambridge University, United Kingdom Jibin Abraham Punnoose, The RNA Institute, University at Albany, USA 2559-Plat 1:00 pm HIGH-THROUGHPUT EXPLORATION OF SEQUENCE SPACE WITH SPARXS: FROM DNA KINETICS TO NUCLEIC ACID-PROTEIN INTERACTIONS. Caro lien Bastiaanssen , Ivo Severins, Chirlmin Joo 2560-Plat 1:15 pm QUANTIFYING THE BASE-STACKING ENERGY IN NUCLEIC ACIDS USING A SINGLE-MOLECULE FORCE CLAMP ASSAY. Jibin Abraham Punnoose , Chai Kam, Dadrian Cole, Ken Halvorsen 2561-Plat 1:30 pm STUDIES OF SUPERCOILING-INDUCED DENATURATION WITHIN DNA PLASMIDS USING SINGLE-MOLECULE CONVEX LENS-INDUCED CONFINE MENT MICROSCOPY. Cynthia Shaheen , Alexis Hilts, Bianca C. Caminada, Zixian Wei, Khaled Skaik, Sabrina R. Leslie 2562-Plat 1:45 pm DISRUPTION OF ENERGETIC AND DYNAMIC BASE-PAIRING COOPERATIV ITY IN DNA DUPLEXES BY AN ABASIC SITE. Brennan Ashwood , Michael S. Jones, Andrew L. Ferguson, Andrei Tokmakoff 2563-Plat 2:00 pm PREFERRED STATES OF SINGLE DNA MOLECULES IN CROWDED SOLU TIONS. Jin Qian, Dylan Collette, Zachary Montgomerie, David Dunlap , Andrew J. Spakowitz, Laura Finzi 2564-Plat 2:15 pm FOLDING OF G-QUADRUPLEXES AND I-MOTIFS IN THE NUCLEUS OF LIV ING CELLS. Brahmmi Patel , Hyejin Yoo, Caitlin Davis 2565-Plat 2:30 pm D-TOPO: ADVANCING TOPOLOGICAL ANALYSIS OF DNA STRUCTURAL DYNAMICS IN HS-AFM REALTIME IMAGES. Connor Cowie , Yi-Chih Lin 2566-FlashTalk 2:45 pm SWITCHBACK DNA: A DOUBLE HELIX WITH A DIFFERENCE. Madhanago pal Barathraj , Hannah Talbot, Arlin Rodriguez, Arun Richard Chandrasek aran 2567-FlashTalk 2:50 pm CONSTRUCTION AND RECONFIGURATION OF DYNAMIC DNA ORIGAMI ASSEMBLIES WITH COILED COIL PATCHES AND PATTERNS. Teng Teng 2568-FlashTalk 2:55 pm PROTAMINE REVIVES DNA ORIGAMI. Shreya Hegde , Oliver Polachini, Alejandra Velasquez, Moumita Dasgupta, Ashley Carter Platform Protein Dynamics and Allostery II 1:00 pm - 3:00 pm, Room 201AB Co-Chairs Yumin Lee, University of Chicago, USA Sarah Rauscher, University of Toronto, Mississauga, Canada 2569-Plat 1:00 pm FUNCTIONAL PROTEIN DYNAMICS IN A CRYSTAL. Eugene Klyshko, Justin S. Kim, Lauren McGough, Victoria Valeeva, Ethan Lee, Rama Rangana than, Sarah Rauscher

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