BPS2024 Full Program & Abstracts

2570-Plat 1:15 pm THERMODYNAMIC STABILITY AS A DETERMINANT OF THE P K A VALUES OF IONIZABLE RESIDUES IN HYDROPHOBIC ENVIRONMENTS IN PRO TEINS. Miranda N. Hurst , Bertrand Garcia-Moreno 2571-Plat 1:30 pm COLLECTIVE VARIABLES CALCULATED BY WEIGHTED ENSEMBLE SIMULA TIONS OF PROTEINS. Hiroshi Fujisaki , Kei Moritsugu 2572-Plat 1:45 pm EXPLORING ALLOSTERIC MECHANISM IN ADENYLATE KINASE: FROM CATALYSIS TO CONFORMATIONAL CHANGES. Kwangho Nam 2573-Plat 2:00 pm Travel Award Winner DIRECT OBSERVATION OF PROTEIN-PEPTIDE FOLDING AND BINDING IN THE FORMATION OF RIBONUCLEASE S. Yumin Lee , Brennan Ashwood, Yiheng Wu, Balamurugan Dhayalan, Isabelle Gagnon, Tobin R. Sosnick, Andrei Tokmakoff 2574-Plat 2:15 pm MODULATION OF ALLOSTERY WITH MULTIPLE MECHANISMS BY HOTSPOT MUTATIONS IN TETR. Jiahua Deng , Yuchen Yuan, Qiang Cui 2575-Plat 2:30 pm GOOD RATES FROM BAD COORDINATES. Nicodermo Mazzaferro, Pilar Cossio , Glen M. Hocky 2576-FlashTalk 2:45 pm ENHANCING PROTEIN DYNAMICS STUDIES WITH AN AUTOMATED FRET NETWORK DESIGN INFORMED BY DIRECT COUPLING ANALYSIS. Aish warya Krishnamohan , George L. Hamilton, F.X. Duffy, Faruck Morcos, Hugo Sanabria 2577-FlashTalk 2:50 pm PRODY’S LATEST ADVANCEMENTS: GAINING INSIGHTS INTO PROTEIN PROTEIN AND PROTEIN-WATER INTERACTIONS, AND THEIR ROLE IN PROTEIN DYNAMICS. Karolina Mikulska-Ruminska , Frane Doljanin, James M. Krieger, Xin Cao, Gary Wu, Anupam Banerjee, Carlos Simmer ling, Evangelos A. Coutsias, Ivet Bahar 2578-FlashTalk 2:55 pm STRUCTURAL BASIS FOR ALLOSTERIC REGULATION OF THE HUMAN CIS PRENYLTRANSFERASE COMPLEX. Moshe Giladi , Ekaterina Positselskaya, Lyr Aviram, Shiri Kredi, Pavla Vaňková, Petr Man, Yoni Haitin Platform Optical Microscopy and Superresolution Imaging III 1:00 pm - 3:00 pm, Room 204AB Co-Chairs Chiara Stringari, École Polytechnique, France Michael Stoneman, University of Wisconsin-Milwaukee, USA 2579-Plat 1:00 pm MODELLING AND PREDICTING SECOND HARMONIC GENERATION FROM PROTEIN MOLECULAR STRUCTURE. Bahar Asadipour, Emmanuel Beau repaire, Xingjian Zhang, Anatole Chessel, Pierre Mahou, Willy Supatto, Marie-Claire Schanne-Klein, Chiara Stringari 2580-Plat 1:15 pm NEURAL NETWORK-ASSISTED SINGLE-MOLECULE LOCALIZATION MICROSCOPY WITH A WEAK-AFFINITY PROTEIN TAG. Soohyen Jang , Kaarjel Narayanasamy, Johanna Rahm, Alon Saguy, Julian Kompa, Ma rina S. Dietz, Kai Johnsson, Yoav Shechtman, Mike Heilemann 2581-Plat 1:30 pm UNVEILING GPCR OLIGOMERIZATION AND ITS FUNCTIONAL SIGNIFI CANCE USING IFRET. Michael R. Stoneman , Dammar N. Badu, Kaleeckal Harikumar, Laurence J. Miller, Valerica Raicu

2582-Plat 1:45 pm INTRACELLULAR OXYGEN DETECTION USING FLUORESCENCE LIFETIME IMAGING OF MYOGLOBIN-MSCARLET. Katie A. Link , Rozhin Penjweini, Han Tran, Nicole Y. Morgan, Jay R. Knutson 2583-Plat 2:00 pm LOCALIZATION OF VIRAL RNA AND PROTEINS IN THE SARS-COV-2 REPLI CATION ORGANELLES REVEALED BY SUPER-RESOLUTION MICROSCOPY. Leonid Andronov , Mengting Han, Yanyu Zhu, Anish R. Roy, Andrew E.S. Barentine, Lei S. Qi, William E. Moerner 2584-Plat 2:15 pm QUANTUM DOTS MICROPATTERNING: TOWARDS BIOFUNCTIONALIZA TION AND NANO-IMAGING. Paul Robineau, Rodolphe Jaffiol, Thomas Pons, Cyrille Vézy 2585-Plat 2:30 pm VISUALIZATION OF ANGIOTENSIN II TYPE 1 RECEPTORS IN THEIR NATIVE CELLULAR ORGANIZATION BY USING EXPANSION MICROSCOPY. Yen isleidy D.L.M. Zulueta Diaz , Thomas M.D. Sheard, Camilla B. Andersen, Izzy Jayasinghe, Eva Arnspang Christensen 2586-FlashTalk 2:45 pm SUPER-RESOLUTION IMAGING REVEALS THE NANOSCALE DISTRIBU TIONS OF DYSTROGLYCAN AND INTEGRIN ITG7A IN ZEBRAFISH MUSCLE FIBERS. Komala Shivanna , Mary Astumian, Prakash Raut, Vinh Nhan Ngo, Samuel T. Hess, Clarissa Henry 2587-FlashTalk 2:50 pm LATTICE LIGHTSHEET DNA-PAINT MICROSCOPY WITH DUAL-LABELED SELF-QUENCHED IMAGER PROBES. Arindam Ghosh , Mara Meub, Domi nic A. Helmerich, Soeren Doose, Markus Sauer 2588-FlashTalk 2:55 pm MESOSCOPIC ARCHITECTURE AND MOLECULAR DYNAMICS IN FOCAL ADHESIONS AS REVEALED BY ULTRAFAST SINGLE-MOLECULE IMAGING. Takahiro Fujiwara Platform Motor Proteins and Cytoskeletal Assemblies III 1:00 pm - 3:00 pm, Room 201C Co-Chairs Kristen Skruber, University of California, San Francisco, USA Margaret Titus, University of Minnesota, USA 2589-Plat 1:00 pm DETYROSINATION ENRICHMENT ON MICROTUBULE SUBSETS IS ES TABLISHED BY THE INTERPLAY BETWEEN A STOCHASTICALLY-ACTING ENZYME AND MICROTUBULE STABILITY. Qing Tang , Sebastian Sensale, Charles Bond, Jiazheng Xing, Andy Qiao, Siewert Hugelier, Arian Arab, Gaurav Arya, Melike Lakadamyali 2590-Plat 1:15 pm IN VIVO FORCE MEASUREMENTS ON FORMIN CDC12P USING NEW COILED-COIL FORCE SENSORS. Takumi Saito , Yuan Ren, Julien Berro 2591-Plat 1:30 pm THE MAJORITY OF MONOMERS ENTER BRANCHED ACTIN NETWORKS FROM A MEMBRANE SURFACE. Kristen Skruber , Dyche Mullins 2592-Plat 1:45 pm WNK1 ACTIVITY MODULATES BIOPHYSICAL PROPERTIES OF GLOMERU LAR PODOCYTES THROUGH REGULATION OF NON-MUSCLE MYOSIN II ACTIVATION. Zhenan Liu, Fouzia Ahmed, Joonho Yoon, R. Tyler Miller, Audrey N. Chang

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