BPS2024 Full Program & Abstracts

2899 -Pos Board B291 STRESS-INDUCED BAG3 CLEAVAGE AND ITS EFFECTS ON SARCOMERE CONTRACTILE FUNCTIONS. Ahmed Zied , Jonathan A. Kirk, Hana Pak, Michaela Door 2900 -Pos Board B292 LEIOMODIN-2 INHIBITS ACTOMYOSIN INTERACTIONS AND PERTURBS THE STRUCTURE OF THE THIN FILAMENT. Cristina M. Risi , Jennifer Atherton, Tyler Nguyen, Howard D. White, Carol Gregorio, Alla S. Kostyu kova, Vitold E. Galkin 2901-Pos Board B293 DECOUPLING CALCIUM DEPENDENT THIN FILAMENT ACTIVATION FROM THICK FILAMENT ACTIVATION IN PORCINE MYOCARDIUM. Saf fie Mohran, Christian Mandrycky, An-yue Tu, Tim McMillen, Kristina B. Kooiker, Wenjing Qian, Thomas C. Irving , Michael Regnier, Weikang Ma 2902 -Pos Board B294 PHENOTYPES OF MICE EXPRESSING A MYOPATHIC EXON 8 DELETION MUTANT OF SLOW SKELETAL MUSCLE TROPONIN T REVEAL NOVEL PATHOGENIC AND PATHOPHYSIOLOGICAL MECHANISM. Han-Zhong Feng , J.-P. Jin 2903 -Pos Board B295 GLOBAL IDENTIFICATION OF PALMITOYLATING ENZYME SUBSTRATES IN CARDIOMYOCYTES PROVIDE MECHANISTIC INSIGHTS INTO WHY UPREGULATION OF THESE ENZYMES AGGRAVATES MYOCYTE INJURY IN RESPONSE TO ISCHEMIA/REPERFUSION. Gea-Ny Tseng , Evgeny Kanshin, Beatrix M. Ueberheide 2904 -Pos Board B296 BIOMARKERS ASSOCIATED WITH THE BARRIER FUNCTION OF SKELETAL MUSCLE IN SUBJECTS WITH MUSCULAR DYSTROPHIES. Paul S. Blank, Adriana E. Golding, Hang Waters , Joshua Zimmerberg Mitochondria in Cell Life and Death (Boards B297 - B318) 2905-Pos Board B297 MITOCHONDRIAL NETWORK PHYSIOLOGY DISRUPTION DURING SARS COV-2 INFECTION IN HUMAN LUNG ORGANOIDS. Gillian McMahon , Zichen Wang, Hiroyuki Hakozaki, Paul Marchando, Cyna R. Shirazinejad, Yuichiro Iwamoto, Anna Ye, David Drubin, Matthew Akamatsu, Johannes Schöneberg 2906-Pos Board B298 PROGRESSION OF HERPESVIRUS INFECTION REMODELS MITOCHONDRI AL ORGANIZATION AND METABOLISM. Simon Leclerc , Visa Ruokolainen, Alka Gupta, Axel Ekman, Jian-Hua Chen, Sergey Kapishnikov, Eric Dufour, Vesa Hytonen, Eva Pereiro, Tony Mc Enroe, Kenneth Fahy, Carolyn Lara bell, Venera Weinhardt, Vesa Aho, Maija Vihinen-Ranta 2907-Pos Board B299 IDENTIFICATION OF AN ALTERNATIVE CALCIUM-INDUCED PATHWAY OF MITOCHONDRIAL DYSFUNCTION. Maria A. Neginskaya , Zoya V. Niatsetskaya, Sergey A. Sosunov, Sally E. Morris, Evgeny V. Pavlov, Vadim S. Ten 2908 -Pos Board B300 DEFINING THE MOLECULAR BASIS AND REGULATION OF MITOCHON DRIAL CO-TRANSLATIONAL PROTEIN IMPORT. Ya-Ting Chang 2909 -Pos Board B301 Travel Award Winner STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF TWO DISTINCT FORMS OF CYCLOPHILIN D IN MAMMALIAN MITOCHONDRIA. Gabriele Coluccino , Diana Canetti, Andrea Urbani, Camilla Bean, Alessandro Ne gro, Antonio Filippi, Valentina P. Muraca, Clarissa Gissi, Michela Carraro, Paolo Bernardi, Alessandra Corazza, Giovanna Lippe

2910-Pos Board B302 PROTONATION-DEPENDENT ION FLUX IN A MITOCHONDRIAL LEAK CHANNEL. Qi Wang , Nelli Mnatsakanyan, Elizabeth A. Jonas, Sally C. Pias 2911-Pos Board B303 OVEREXPRESSION OF MITOCHONDRIAL BKCA CHANNELS REDUCES ROS IN A HIGH-THROUGHPUT HYPOXIA/REOXYGENATION MATRIX-HYPER7 ROS ASSAY. Joseph Ousus-Sarfo , Aguocha Benison, Wenzhuo Ma, Dmi try Terentyev, Richard T. Clements, Clarissa F. Cavarsan-Muller 2912-Pos Board B304 EFFECT OF LITHIUM ISOTOPES ON SODIUM/LITHIUM/CALCIUM EXCHANGER IN MITOCHONDRIA. Irina Bukhteeva , Fasih A. Rahman, Evgeny Pavlov, Robin Duncan, Joe Quadrilatero, Brian Kendall, Michel Gingras, Zoya Leonenko 2913-Pos Board B305 NOVEL APPROACH FOR EVALUATION OF MITOCHONDRIAL SUBSTRATE UNITILIZATION IN FIBROBLASTS FROM PATIENTS WITH FRIEDREICH’S ATAXIA. Nazanin Ahmadian, Sabrina Dallas, Elena N. Dedkova 2914-Pos Board B306 MITOCHONDRIAL BK CHANNELS IN SENESCENT VASCULAR SMOOTH MUSCLE CELLS. Adam M. Szewczyk 2915-Pos Board B307 DOXORUBICIN TOXICITY INDUCES MITOCHONDRIAL RETROGRADE SIG NALING IN AC16 CELLS. Yi-Ju Lee, Yu-Te Lin, Wen-Wei Tseng, An-Chi Wei 2916-Pos Board B308 Travel Award Winner MEASURING THE MITOCHONDRIAL OUTER MEMBRANE POTENTIAL IN LIVE CELLS. Kaitlin Abrantes , Sergey M. Bezrukov, Tatiana K. Rostovt seva, Megha Rajendran 2917-Pos Board B309 VDAC ISOFORMS DIFFERENTIALLY REGULATE MITOCHONDRIAL PRO TEOME AND RESPIRATION IN CANCER CELLS. Megha Rajendran , William M. Rosencrans, Julie Hwang, Baiyi Quan, Diana Huynh, Tsui-Fen Chou, Sergey M. Bezrukov, Tatiana K. Rostovtseva 2918-Pos Board B310 OPENING OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE AS A KEY COMPONENT IN THE MITOCHONDRIAL-JUNCTIONAL SARCOPLASMIC RETICULUM INTERFACE IN CARDIOMYOCYTES. Marilen Federico , Leandro Sommese, Hui-Ying Tsai, Facundo Barraque, Gyorgy Csordas, Shey-Shing Sheu 2919-Pos Board B311 RHODOTORULA MUCILAGINOSA SURVIVES UNDER EXTREME CONDI TIONS BY USING AND CONTROLLING BOTH, A BRANCHED RESPIRATORY CHAIN AND CAROTENOID SYNTHESIS. Salvador Uribe-Carvajal , Paulina Castañeda Tamez, Ofelia A. Mendez Romero, Carolina Ricardez García, Edson Erivan Mosqueda Martínez, Paola Acosta Valdelamar, Mauricio Reyes Becerril, Natalia Chiquete Felix, Alfredo Cabrera Orefice 2920 -Pos Board B312 SELECTIVE METABOLIC INTERFERENCE WITH NOVEL VA MOLECULES TARGETING VDAC1 IN CANCER CELLS. Stefano Conti Nibali, Silvia De Siervi, Enrico Luchinat, Andrea Magrì, Lorenza Brocca, Mario U. Mon delli, Vito De Pinto, Cristian Turato, Cristina Arrigoni, Marco Lolicato 2921-Pos Board B313 MEMBRANE INTERACTION AND BINDING OF THE DISPLACED VDAC1 N-TERMINUS. Po-Chao Wen , Wai-Meng Kwok, Emad Tajkhorshid 2922 -Pos Board B314 VDAC-DEPENDENT MITOCHONDRIAL METABOLISM AND CELL PROLIF ERATION DIFFER BETWEEN VDAC KNOCKOUT AND TRANSIENT INHIBI TION OF VDAC EXPRESSION. Florencia X. Santiago Valtierra, Milagros Junco, Clara Ventura, D. Sanchez-Gonzalez, R. Ward, Itsaso Garcia-Arcos, Jessica H. Hartman, Eduardo N. Maldonado

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