BPS2024 Full Program & Abstracts

200-Plat 5:15 pm TUNING PROTEIN FUNCTION: RHEOSTATS, TOGGLES, AND NEUTRALS, OH MY! Liskin Swint-Kruse 201-Plat 5:30 pm DYNAMICS OF SURFACTANT PROTEIN B AT THE ALVEOLAR AIR-LIQUID INTERFACE: INSIGHTS FROM MOLECULAR MODELING AND SIMULA TIONS. Mona Minkara , Tyler Locke 202-FlashTalk 5:45 pm HLA3DB: COMPREHENSIVE ANNOTATION OF PEPTIDE/HLA COMPLEXES ENABLES BLIND STRUCTURE PREDICTION OF T CELL EPITOPES. Sagar Gupta , Santrupti Nerli, Sreeja Kutti Kandy, Glenn L. Mersky, Nikolaos Sgourakis 203-FlashTalk 5:50 pm DESIGN OF PROTEIN FOLD-SWITCHES USING ALCHEMICAL MUTATION FREE ENERGY CALCULATIONS. Lisa Schmidt , Bert L. de Groot 204-FlashTalk 5:55 pm Travel Award Winner DIRECT PREDICTION OF INTRINSICALLY DISORDERED PROTEIN CONFOR MATIONAL PROPERTIES FROM SEQUENCE. Jeffrey M. Lotthammer , Garrett M. Ginell, Daniel Griffith, Ryan Emenecker, Alex S. Holehouse Platform Computational Methods and Machine Learning, Artificial Intelligence, and Bioinformatics I 4:00 pm - 6:00 pm, Room 204AB Co-Chairs Nikos Hatzakis, University of Copenhagen, Denmark Eduardo Rios, Rush University, USA 205-Plat 4:00 pm CANCELED 206-Plat 4:15 pm EXPECTATION MAXIMISED MOLECULAR DYNAMICS: AN UNSUPERVISED MACHINE LEARNING APPROACH TOWARDS RAPID ESTIMATION OF BIOMOLECULAR TRANSITION BARRIERS. Neelanjana Sengupta , Pallab Dutta, Abhay Kshirsagar, Parth Bibekar 207-Plat 4:30 pm DEEP-SPT A DEEP LEARNING TOOLBOX FOR SINGLE PARTICLE TRACKING IN 3D REVEALS HOW BIOLOGICAL MOTION ENCODES FUNCTION. Jacob Kæstel-Hansen, Tom Kirchhausen, Nikos S. Hatzakis 208-Plat 4:45 pm OPTIMIZATION AND HISTORICAL CONTINGENCY IN PROTEIN SEQUENC ES. Anne-Florence Bitbol 209-Plat 5:00 pm Travel Award Winner CAPTURING THE BIOMECHANICS OF SARS-COV-2/ANTIBODY COMPLEX ES BY GŌMARTINI SIMULATION. Luis F. Cofas-Vargas , Adolfo Poma 210-Plat 5:15 pm DEEP LEARNING CONVOLUTIONAL NEURAL NETWORKS FOR THE QUAN TIFICATION OF GLYCOGEN IN ELECTRON MICROGRAPHS OF CALCIUM STRESSED HUMAN MUSCLE. Eduardo Rios , Montserrat Samso, Eshwar Reddy Tammineni, Lourdes C. Figueroa, Carlo D. Manno, Sheila Riazi 211-Plat 5:30 pm ARE PHASES AN APPROPRIATE DESCRIPTION FOR CELLS? - FLUCTUATION DOMINATED REGIME IN FINITE SYSTEMS WITH MANY COMPONENTS. Martin Girard

212-FlashTalk 5:45 pm QUANTIFYING BIOLOGICAL VARIABILITY USING APPROPRIATE DATA REP RESENTATIONS OF MICROSCOPY IMAGES. Ritvik Vasan , Julie Theriot, Matheus Palhares Viana, Susanne M. Rafelski 213-FlashTalk 5:50 pm FROM STATIC TO DYNAMIC: RAPID MAPPING OF PROTEIN CONFORMA TIONAL TRANSITIONS USING DEEPPATH. Yui Tik Pang , Lixinhao Yang, James C. Gumbart 214-FlashTalk 5:55 pm 3D BARCODED RNA FISH WITH BAYESIAN UNCERTAINTY QUANTIFICA TION. Max Schweiger , Sina Jazani, Rory Kruithoff, Alexis Coullomb, Douglas P. Shepherd, Steve Pressé Platform Motor Proteins and Cytoskeletal Assemblies I 4:00 pm - 6:00 pm, Room 201C Co-Chairs Andrea Lopez Moreno, University of Bergen, Norway Carolyn Moores, Birkbeck, University of London, United Kingdom 215-Plat 4:00 pm MULTICOMPONENT REGULATION OF ACTIN BARBED END ASSEMBLY BY TWINFILIN, FORMIN AND CAPPING PROTEIN. Heidi Ulrichs, Ignas Gaska, Shashank Shekhar 216-Plat 4:15 pm CORTACTIN STABILIZES ACTIN BRANCHES BY BRIDGING ACTIVATED ARP2/3 TO ITS NUCLEATED ACTIN FILAMENT. Tianyang Liu, LuYan CAO, Miroslav Mladenov, Antoine G. Jegou, Michael Way, Carolyn A. Moores 217-Plat 4:30 pm Travel Award Winner THE EXCLUSION OF NON-MUSCLE MYOSIN-2 IS REQUIRED FOR MICRO VILLI ACTIN MAINTENANCE IN HUMAN CELLS. Cameron A.R. Mitchell, Andrew T. Lombardo 218-Plat 4:45 pm INTERACTION OF MYOPALLADIN WITH ACTIN IS CRITICAL FOR CARDIAC DEVELOPMENT. Asha Rankoth Arachchige, Oluwatosin Ajiboye, Vinay Kumar Kadarla, Julie Tran, Alia M. Michaelis, Ziwei Zhao, Erika R. Geis brecht, Moriah R. Beck 219-Plat 5:00 pm Travel Award Winner IN VITRO INTERACTION OF MYELIN PROTEINS P0 , P2,AND MBP WITH F-ACTIN. Andrea J. Lopez Moreno , Petri Kursula 220-Plat 5:15 pm MECHANISM OF MICROTUBULE ASSEMBLY BY CKAP2. Susanne Bechst edt , Tanya Lyalina, Lia Paim 221-Plat 5:30 pm SIMULTANEOUS TRACKING OF MULTIPLE DYNAMIC MICROTUBULE TIPS IN TIME-LAPSE MICROSCOPY IMAGES. Wonmuk Hwang , Goker Arpag, Veronica J. Farmer, Elizabeth Lawrence, Marija Zanic 222-FlashTalk 5:45 pm OPTIMIZATION OF A MACHINE-LEARNING-BASED APPROACH TO QUANTIFY AND CHARACTERIZE MICROTUBULE DYNAMIC INSTABILITY. Sayandeepa Raha 223-FlashTalk 5:50 pm ANILLIN PROMOTES ACTOMYOSIN CONTRACTILITY BY MECHANICAL TETHERING. Pavlina Slikova , Alexandre Beber, Stepanka Tomasova, Teije C. Middelkoop, Allan Akandwanaho, Lenka Libusova, Marcus Braun, Zdenek Lansky

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