BPS2024 Full Program & Abstracts

393-Pos Board B159 MECHANISMS OF AMYLOID-MEMBRANE INTERACTIONS AND PREVEN TIVE APPROACHES IN ALZHEIMER'S DISEASE. Carina T. Filice, Nanqin Mei, Yue Xu, Danielle M. McRae, Zoya Leonenko 394-Pos Board B160 ATP PREVENTS AGGREGATION VIA MODULATION OF PROTEIN CONFOR MATION. Susmita Sarkar , Jagannath Mondal 395-Pos Board B161 MOLECULAR BASIS FOR YEAST UBIQUILIN DSK2 SELF-ASSOCIATION AND PHASE SEPARATION. Nirbhik Acharya , Thuy P. Dao, Erica Mallon, Erin Mulvey, Dan Kraut, Carlos A. Castaneda 396-Pos Board B162 TRANSFER FREE ENERGY PREDICTS OSMOLYTE-INDUCED STRUCTURAL AND FUNCTIONAL CHANGES IN INTRINSICALLY DISORDERED PRO TEINS. Vincent M. Nicholson DNA Replication, Recombination, and Repair (Boards B163 - B178) 397-Pos Board B163 AN EFFICIENT BIOCHEMISTRY PLATFORM TO INCORPORATE REPLICA TION FORKS, DNA LEASIONS AND NUCLEOSOME ARRAYS TO SINGLE MOLECULE EXPERIMENTS. Matthew Dilsaver , Marco Simonetta, Bas Groen, Mattijs de Groot, Trey Simpson 398-Pos Board B164 TARGETING BACTERIAL DNA GYRASE AND TOPOISOMERASE IV IN VITRO AND IN VIVO BY A NEWLY IDENTIFIED QUINAZOLINE GYRASE INHIBI TOR. Ayesha Nawaz , Eddy Alfonso, Zifang Deng, Fenfei Leng 399-Pos Board B165 RECOMBINASE MEDIATOR MEI5-SAE3 STIMULATES DMC1 RECOMBI NASE ASSEMBLY ON RPA-COATED SSDNA BY STABILIZING NUCLEATION CLUSTERS. Chin-Dian Wei , Hao-Yen Chang, Hung-Yuan Chi, Hung-Wen Li 400-Pos Board B166 ELUCIDATION OF THE ROLES OF THE DNAE-SSB AND DNAE-DNAN INTERACTIONS IN BACILLUS SUBTILIS DNA REPLICATION AT THE SINGLE MOLECULE LEVEL. Luke G. O'Neal , Emily E. Holmes, Lindsey E. Way, Sinwoo Hong, Xindan Wang, Elizabeth S. Thrall 401-Pos Board B167 STUDYING THE DYNAMICS AND MECHANISMS OF GP32-GP59 PROTEIN ASSEMBLIES AT (ICY3) 2 -LABELED SS-DSDNA JUNCTIONS BY ENSEMBLE AND SINGLE-MOLECULE TECHNIQUES. Khulan Enkhbaatar , Jack W. Maurer, Dylan Heussman, Sophia Hodgdon, Peter H. von Hippel, Andrew H. Marcus 402-Pos Board B168 UNPARALLELED APPROACHES TO DIRECTLY VISUALIZE DNA-BINDING PROTEINS AND BIOMOLECULAR CONDENSATES. Trey Simpson , Bas Groen, Andrea Candelli 403-Pos Board B169 INVESTIGATING THE ROLE OF THE INTERACTION BETWEEN THE DNAN CLAMP AND THE TRANSLESION POLYMERASE POL Y1 IN B. SUBTI LIS. Chloe Santana , McKayla E. Marrin, Michael R. Foster, Elizabeth S. Thrall 404-Pos Board B170 REGULATION OF DNA END RESECTION BY THE WERNER SYNDROME HELICASE. Ian Mawn, Michael M. Soniat

405-Pos Board B171 SUPER-RESOLUTION IMAGING AND SINGLE-MOLECULE TRACKING OF RNA-DNA HYBRID PROCESSING PROTEINS IN BACILLUS SUBTILIS . Daniel J. Foust , Ziyuan Chen, Julianna R. Cresti, Frances C. Lowder, Lyle A. Sim mons, Julie S. Biteen 406-Pos Board B172 Travel Award Winner REGULATION OF THE REAL TIME KINETICS OF THE HUMAN MITO CHONDRIAL REPLICATIVE HELICASE BY DNA FORK AND REPLISOME FACTORS. Ismael Plaza García-Abadillo , Kateryna Lemishko, Grzegorz L. Ciesielski, Borja Ibarra 407-Pos Board B173 REAL-TIME VISUALIZATION OF BLM HELICASE INDUCED DNA UNWIND ING. Shyla Singh , Andreas S. Biebricher, Colleen Caldwell, Ian D. Hickson, Gijs J.L. Wuite 408-Pos Board B174 ENHANCEMENT OF HOMOLOGY DIRECTED REPAIR IN YEAST USING AN ARTIFICIAL DNA LOOPING PROTEIN. Ian T. Ferencz, Emma R. Neis wender , Jason D. Kahn 409-Pos Board B175 SINGLE-MOLECULE VISUALIZATION OF TRANSLESION POLYMERASE ACTIVITY IN BACILLUS SUBTILIS . McKayla E. Marrin, Michael R. Foster, Chloe M. Santana, Yoonhee Choi, Avtar S. Jassal, Sarah J. Rancic, Carolyn R. Greenwald, Madeline N. Drucker, Elizabeth S. Thrall 410-Pos Board B176 FUNCTIONAL CONTRIBUTION OF CONDENSATE FORMATION BY SINGLE STRANDED DNA BINDING PROTEIN (SSB) TO BACTERIAL GENOME MAINTENANCE. Peter Ecsédi , János Pálinkás, Zoltán Kovács, Gábor Harami, Tunde Juhasz, Balint Jezso, David Erfalvy, Lamiya Mahmudova, Eszter Házy, Tamas Beke-Somfai, Mihaly Kovacs 411-Pos Board B177 RECONSTITUTION AND SINGLE MOLECULE CHARACTERIZATION OF T. AQUATICUS BETA CLAMP LOADING ONTO DNA BY THE CLAMP LOADER COMPLEX. Rachel Evans , Keith R. Weninger 412-Pos Board B178 Travel Award Winner SINGLE-MOLECULE IMAGING TO PROBE THE CLAMP LOADER MECHAN ICS OF MUTS WITH MUTL. Xiaowen Yang , Xiao-Peng Han, Richard Fishel, Jiaquan Liu DNA Structure and Dynamics I (Boards B179 - B205) 413-Pos Board B179 MECHANISM OF DAMAGE RECOGNITION BY RAD4/XPC IN LINEAR AND CIRCULAR DNA. Saroj Baral , Sagnik Chakraborty, Debamita Paul, Ying Pigli, Peter J. Steinbach, Jung-Hyun Min, Phoebe A. Rice, Anjum Ansari 414-Pos Board B180 FROM LOOPS TO STACKS: EARLY STEPS IN THE DNA FOLDING PATHWAY BY PROTAMINE. Alejandra Velasquez , Ryan B. McMillan, Hilary Bediako, Luka Matej Devenica, Isabel Hardy, Yuxing E. Ma, Donna M. Roscoe, Ashley Carter 415-Pos Board B181 STABILITY DIFFERENCES BETWEEN RIGHT- AND LEFT-HANDED G-QUA DRUPLEXES - EXPLAINED BY MOLECULAR DYNAMICS SIMULATIONS. Mi chal Jurkowski , Mateusz Kogut, Jacek Czub 416-Pos Board B182 TORSIONAL STIFFNESS OF EXTENDED AND PLECTONEMIC DNA. Xiang Gao, Yifeng Hong , Fan Ye, James Inman, Michelle D. Wang

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