BPS2024 Full Program & Abstracts

Platform Membrane Protein Dynamics 10:45 am - 12:45 pm, Room 201AB

929 -FlashTalk 12:40 pm STRUCTURAL BASIS OF PARTITIONING BETWEEN TERMINATION AND ANTITERMINATION OF THE FLUORIDE RIBOSWITCH. Emily Ellinger Platform Intrinsically Disordered Proteins II 10:45 am - 12:45 pm, Room 113AB Co-Chairs Shreya Ghosh, NIDDK, NIH, USA Samuel Wohl, Arizona State University, USA 930 -Plat 10:45 am ATOMIC-SCALE STRUCTURAL INSIGHTS INTO FUNCTIONAL ROLE OF LONG INTRINSICALLY DISORDERED REGION OF HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 (HNRNPA1). Irawati Roy 931-Plat 11:00 am QUANTITATIVE NMR ANALYSIS OF THE MECHANISM AND KINETICS OF CHAPERONE HSP104 ACTION ON amYLOID Β-42 AGGREGATION AND FIBRIL FORMATION. Shreya Ghosh , Vitali Tugarinov, G. Marius Clore 932 -Plat 11:15 am VISUALIZATION AND TRANSPORT THROUGH BIOMIMETIC NUCLEAR PORE COMPLEXES. Eva Bertosin , Nils Klughammer, Anders Barth, Jacob W.J. Kerssemakers, Eli van der Sluis, Cees Dekker 933 -Plat 11:30 am TDP-43 DERIVED Α-HELICAL PEPTIDES: A NOVEL STRATEGY TO PREVENT TDP-43 AGGREGATION IN NEURODEGENERATIVE DISORDERS. Muthu Raj Salaikumaran , Pallavi P Gopal 934 -Plat 11:45 am INTRINSICALLY DISORDERED REGIONS IN KATP CHANNELS ARE ALLOSTE RICALLY COUPLED. Ethan Lee , Agatha Tymczak, Sarah Rauscher, Voula Kanelis 935-Plat 12:00 pm PROBING THE MICROSTRUCTURE OF PATHOLOGICAL PROTEIN DEPOS ITS IN ALZHEIMER’S DISEASE. Abdullah Al Bashit , Prakash Nepal, Lee Makowski 936-Plat 12:15 pm EFFECTS OF HYDROPHOBIC SEQUENCE PATTERNS ON DISORDERED PROTEIN CONFORMATIONAL ENSEMBLES. Cedrick D. Mukinay , Michael C. Baxa, Tobin R. Sosnick, Patricia L. Clark 937-FlashTalk 12:30 pm IMPACT OF TRANSIENT INTERACTIONS ON BIOMOLECULAR CONDEN SATES. Samuel Wohl , Wenwei Zheng 938 -FlashTalk 12:35 pm CHARGE-DRIVEN DYNAMICAL HETEROGENEITY IN THE INTRINSICALLY DISORDERED C-TERMINAL OF PHOSPHATASE FCP1. Lillian Otteson , Kevin Namitz, Gerdenis Kodis, Scott A. Showalter, Sara M. Vaiana 939 -FlashTalk 12:40 pm MOLECULAR DYNAMICS STUDY OF THE INTERACTIONS BETWEEN amYLOID BETA AND LIPID BILAYERS WITH DIFFERENT COMPOSITIONS. Gabriel Chaves Cathoud Pinheiro , Mohtadin Hashemi, Yuri L. Lyubchen ko, Pedro Nuno das Neves Lopes Simões

M O N D A Y

Co-Chairs Lasse Desdorf, Aarhus University, Denmark Shushu Wei, The University of Tennessee Knoxville, USA 940 -Plat 10:45 am

COMPETITION FOR SORTILIN - A TRANSMEMBRANE LOVE STORY. Lasse M. Desdorf , Malene Overby, Nils A. Berglund, Heidi K. Müller, Birgit Schiøtt 941-Plat 11:00 am Travel Award Winner USING HDX-MS TO PROBE THE DYNAMICS AND FREE ENERGY SURFACE OF GLPG, A HELICAL MEMBRANE PROTEIN. Abigail L. Schroeter , Saba Kanwal, Heedeok Hong, Tobin R. Sosnick 942 -Plat 11:15 am MOLECULAR SIMULATION FOR SAFER PSYCHEDELIC THERAPIES. Carl Mikael Suomivuori , Ron O. Dror 943 -Plat 11:30 am THE CURIOUS CASE OF THE GLYCOSYLATED BACTERIAL EFFLUX PUMP: THE CMEABC SYSTEM FROM C. JEJUNI. Syma Khalid , Kahlan E. Newman 944 -Plat 11:45 am STUDYING MEMBRANE PROTEIN LIPID REGULATION IN REAL TIME. Konstantinos Magkakis , Fredrik Orädd, Irfan Prabudiansyah, Magnus P. Andersson 945-Plat 12:00 pm LIGHT-INDUCED INTRAMOLECULAR DOMAIN DYNAMICS OF LIGHT HARVESTING PROTEIN LH1-RC OBSERVED BY THE DIFFRACTED X-RAY BLINKING METHOD. Tatsunari Ohkubo , Kazuhiro Mio, Yuji C. Sasaki 946-Plat 12:15 pm DOMAIN COUPLING IN ACTIVATION OF A CLASS C GPCR. Naomi R. Latorraca , Sam Sabaat, Chris Habrian, Julia Bleier, Susan Marqusee, 12:30 pm VISUALIZING THE STRUCTURAL DYNAMICS OF G PROTEIN-ACTIVATED A 2A ADENOSINE RECEPTOR AT THE SINGLE-MOLECULE LEVEL. Shushu Wei , Niloofar Gopal Pour, Sriram Tiruvadi Krishnan, Arka Prabha Ray, Naveen Thakur, Rajan Lamichhane, Matthew T. Eddy 948 -FlashTalk 12:35 pm DRUGGABLE AND ALLOSTERIC POCKET PRINTS OF G-PROTEIN COUPLED RECEPTORS. Sophie Liu , Umur A. Turgut, Burak T. Kaynak, Ivet Bahar, 12:40 pm SUPER-RESOLUTION INSIGHTS INTO THE ROLE OF ESYT1 IN ER-PM JUNCTION DYNAMICS IN SENSORY NEURONS. Char Palfrey , Nikita Gamper, Shihab S. Shah Platform Single Molecule Spectroscopy and Imaging 10:45 am - 12:45 pm, Room 204AB Co-Chairs Daniel Burden, Wheaton College, USA Errika Voutyritsa, University of Copenhagen, Denmark 950-Plat 10:45 am SIMULTANEOUS ELECTRICAL AND SINGLE-MOLECULE FLUORESCENCE DETECTION IN WINDOWED MICROELECTRODE CAVITY ARRAYS. Lily Anne Van Ye, Richard D. Michael, Joshua J. Meyer, Elizabeth C. Meyer, Lisa M. Burden, Daniel L. Burden Ehud Y. Isacoff 947-FlashTalk Pemra Doruker 949 -FlashTalk

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