BPS2024 Full Program & Abstracts

951-Plat 11:00 am MULTIPLEXED SINGLE-MOLECULE FLUORESCENCE MEASUREMENTS ENABLED BY MULTI-PARAMETER SPECTROSCOPIC DETECTION OF NANOSTRUCTURED FRET LABELS. Jiachong Chu , Ayesha Ejaz, Kyle Lin, Allison Squires 952-Plat 11:15 am MEASURING TRANSITION PATHS OF PROTEIN FOLDING WITH SINGLE MOLECULE FRET AND ZERO-MODE WAVEGUIDES. Chi-Jui Feng , Ulrich Baxa, Hoi Sung Chung 953-Plat 11:30 am OPTICAL SINGLE-MOLECULE RECORDINGS IN MEMBRANE TETHERS. Madeleine R. Howell , Adam E. Cohen 954-Plat 11:45 am TRANSMEMBRANE BILAYER COUPLING IN LIVE CELL MEMBRANES - AN ALEX-IMAGING FCCS STUDY. Thorsten Wohland , Daniel Aik 955-Plat 12:00 pm DNANTENNA: A MODULAR DNA ORIGAMI PLATFORM FOR TRACKING DNA BENDING. Lauren P. Takiguchi, Ryan J. Fantasia , amanda L. Wacker, Boyu Liu, Konlin Shen, Pallav Kosuri 956-Plat 12:15 pm SWITCHABLE ENZYME BIOHYBRIDS FOR GREEN CHEMISTRY DETERGEN CY APPLICATIONS. Errika Voutyritsa , Athanasios Oikonomou, Thomai Lazou, Emily Claire Winther Sørensen, Sune M. Christensen, Kelly Velo nia, Nikos S. Hatzakis 957-FlashTalk 12:30 pm HETEROGENEITY IN CONDENSATES REGULATES INTRA-CONDENSATE DIFFUSION OF RNA SINGLE MOLECULES. Guoming Gao , Emily Sumrall, 12:35 pm TOWARDS SINGLE-MOLECULE STRUCTURAL PROTEOMICS WITH DNA NANOSWITCH CALIPERS. Prakash Shrestha , Darren Yang, William M. Shih, Wesley P. Wong 959-FlashTalk 12:40 pm PROTEIN FINGERPRINTING USING MULTIPOINT SINGLE MOLECULE STRUCTURAL ANALYSIS. Bhagyashree S. Joshi , Chirlmin Joo Platform Membrane Pumps, Transporters, and Exchangers 10:45 am - 12:45 pm, Room 201C Co-Chairs Reza Dastvan, Saint Louis University School of Medicine, USA Jessica Swanson, University of Utah, USA 960-Plat 10:45 am LIGAND-DEPENDENT CONFORMATIONAL DYNAMICS OF LEUT-FOLD MHST IN DETERGENT AND LIPID ENVIRONMENTS. Alexandra C. Schwartz , Matthias Quick, Richard A. Stein, Hassane S. Mchaourab 961-Plat 11:00 am THE MECHANISM OF MAMMALIAN PEPTIDE TRANSPORTERS. Simon M. Lichtinger , Simon Newstead, Philip C. Biggin 962-Plat 11:15 am EFFECT OF ATP AND NON-HYDROLYSABLE ANALOGS ON THE NUCLEO TIDE BINDING DOMAIN DIMERIZATION OF A HUMAN ABC TRANSPORT ER. Maria E. Zoghbi 963-Plat 11:30 am NUCLEOTIDE DEPENDENT CONFORMATIONAL DYNAMICS OF PEPTIDASE DOMAIN CONTAINING ABC TRANSPORTER. Ruojig Zhang , Kevin Jages sar, Hassane Mchaourab, Erkan Karakas Nils G. Walter 958-FlashTalk

964-Plat 11:45 am MULTISCALE KINETIC MODELING REVEALS FUNDAMENTAL DIFFERENC ES BETWEEN ELECTRICALLY- AND CHEMICALLY-DRIVEN ION TRANSPORT. Jessica M.J. Swanson 965-Plat 12:00 pm STRUCTURAL BASIS OF PH-DEPENDENT ACTIVATION IN A CLC TRANS PORTER. Eva Fortea, Sangyun Lee , Rahul Chadda, Janice L. Robertson, Olga Boudker, Alessio Accardi 966-Plat 12:15 pm CANCELED AN ION-INDEPENDENT INTERMEDIATE UNDERLIES THE EVOLUTION ARY SWITCH BETWEEN SODIUM AND PROTON-COUPLED GLUTAMATE TRANSPORTER HOMOLOGUES. Krishna Reddy , Burha Rasool, Olga Boudker 967-FlashTalk 12:30 pm OPPOSITE EFFECTS OF EXTRACELLULAR CHLORIDE AND PH ON CLOSELY RELATED CLC-6 AND CLC-7 TRANSPORTERS SUGGEST NON-OVERLAP PING FUNCTION IN ENDO-LYSOSOMES. Maria Antonietta Coppola , Paola Gavazzo, Ilaria Zanardi, Abraham Tettey-Matey, Antonella Lianto nio, Paola Imbrici, Peying Fong, Michael Pusch 968-FlashTalk 12:35 pm INVESTIGATION OF GABA TRANSPORT AND THE GABA/NA + RELATION SHIP IN HUMAN GAT1 USING SOLID SUPPORTED MEMBRANE-BASED ELECTROPHYSIOLOGY. Rocco Zerlotti , Maria Barthmes, Andre Bazzone 969-FlashTalk 12:40 pm PROTON-DRIVEN ALTERNATING ACCESS AND BROAD-SPECIFICITY IN SPNS LIPID TRANSPORTERS. Samantha Gies, Kevin Jagessar, Ali Rasouli, Sepehr Dehghani-Ghahnaviyeh, Ian Miller, Emad Tajkhorshid, Reza Dastvan Platform Cell Mechanics, Mechanosensing and Motility 10:45 am - 12:45 pm, Room 204C Co-Chairs Poul Bendix, Niels Bohr Institute, University of Copenhagen, Denmark Emmanuèle Helfer, Centre national de la recherche scientifique (CNRS), France 970-Plat 10:45 am COMPUTATIONAL MODELING ESTABLISHES MECHANOTRANSDUCTION AS A POTENT ENTRAINMENT CUE FOR THE MAMMALIAN CIRCADIAN CLOCK. Emmet A. Francis , Padmini Rangamani 971-Plat 11:00 am ENHANCED CELL VISCOSITY AS A NEW PHENOTYPE ASSOCIATED WITH LAMIN A/C ALTERATIONS. Emmanuèle Helfer , Cécile Jebane, Alice Anais Varlet, Marc Karnat, Annie Viallat, Catherine Badens, Jean-Fran çois Rupprecht 972-Plat 11:15 am ACTIVE CELL DIVISIONS GENERATE FOURFOLD ORIENTATIONALLY OR DERED PHASE IN LIVING TISSUE. Fengshuo Yang 973-Plat 11:30 am ADAPTATION TO MECHANICAL STRESSES DRIVES AN APOPTOSIS RESISTANT AND INVASIVE PHENOTYPE IN LIVER CELLS. Xiangyu Gong , Noriyoshi Ogino, Maria de Fátima Leite, Zehua Chen, Ryan Nguyen, Ray mond Liu, Emma Kruglov, Kaitlin Flores, Aiden Cabral, Gabriel Moreira de M. Mendes, Barbara E. Ehrlich, Michael Mak 974-Plat 11:45 am CANCER CELL MECHANOTYPES DEPENDENT ON ECM PROPERTIES DRIVE TUMOR PROGRESSION THROUGH EXTRACELLULAR VESICLE PRODUC TION. Kshitiz Parihar , Jonathan Nukpezah, Phyoe K. Myint, Di-Ao Liu, Ghmkin Hassan, Tobias Baumgart, Valerie M. Weaver, Wei Guo, Paul A. Janmey, Ravi Radhakrishnan

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