BPS2025 Full Program

Lights, Camera, Action: Biophysics in the City of Angels

Program

The Biophysical Society is grateful to its Industry Partners.

GOLD SILVER

Learn more about becoming a Biophysical Society Industry Partner at www.biophysics.org/advertising.

Celebrate the 10th Annual Biophysics Week – A Milestone Event! Biophysics Week is your chance to promote, educate, celebrate, and engage others in the world of biophysics research. This year marks a special milestone as we commemorate the 10th anniversary of Biophysics Week, making it a great opportunity to highlight the progress and advancements in our field. GET INVOLVED! Plan to participate in BPS-sponsored events and explore virtual or local Affiliate Events. We invite you to host your own Biophysics Week Affiliate Event and register it (at no cost) with BPS to receive promotional support. Let’s make this year unforgettable with events that inspire and connect. GEAR UP! Celebrate the 10th Annual Biophysics Week in style! This year’s commemorative Biophysics Week t-shirt is now available. Pre-order online or grab yours at the Society Booth before they sell out. SUPPORT BIOPHYSICS WEEK! Spread the word! Use the tools and resources on the BPS website to share Biophysics Week with your peers, colleagues, and friends. Let’s highlight the importance of biophysics and its contributions to science. #BiophysicsWeek Let’s make the 10th Annual Biophysics Week an inspiring celebration of science, discovery, and community! Visit biophysics.org/ BiophysicsWeek for more information.

GUIDE TO THE ANNUAL MEETING

About the BPS Annual Meeting The Biophysical Society (BPS) Annual Meeting is the largest gathering of biophysicists in the world. With over 200 sessions and more than 3,000 poster presentations, it can be overwhelming! Use this guide to help you get the most from your attendance at this world famous event.

Scientific Sessions The BPS Annual Meeting is known for its many types of sessions, often taking place concurrently. Each type has its own distinct scope, format, and speaker makeup. Symposia Workshops • Technique-oriented sessions

Professional Development The Annual Meeting includes daily sessions and resources for the professional development of biophysicists at all stages of their careers: undergrads and grad students, early and mid-stage, and senior scientists. These sessions are held before, after, and in-between the scientific sessions.

• Broad topics featuring talks by leading researchers presenting new research • Four invited speakers in addition to one “symp select” talk chosen from among submitted abstracts per two hour session • Two-to-three held concurrently Platforms • More focused topics selected from among submitted abstracts held concurrently with symposia • Seven speakers, including early career researchers and three flash talks per two-hour session; flash talk present ers will also present their work in a poster session • Approximately six held concurrently during each symposium session

Workshops On networking, public speaking, teaching and science education, careers in industry and academia, and optimizing graduate and postdoc experiences Exhibits Over 120 displays of new equipment, publications, and products Exhibitor Presentations Hands-on demonstrations conducted by exhibiting companies of scientific products and their uses

Career Development Center Open all day, includes job and resume postings, interview scheduling, CV reviews, and job-related workshops Breakfasts For students and postdocs to network and learn about available resources Panel Discussions Expert presentations on career options, guidance on career transitions, funding resources, science policy

• Four invited speakers in addition to one “workshop select” talk chosen from among submitted abstracts per two-hour session • Four held concurrently on Tuesday evening Subgroup Symposia • Scientific sessions held Saturday • Feature speakers presenting the latest research in biophysics subfields • Include Postdoc and Student talks, awards presentations, and Subgroup business meetings Biophysical Society Lecture • One-hour presentation by a world-renowned biophysicist

Posters Most interactive and well-attended scientific sessions of the meeting. Poster Presenters Share their latest research and engage in discussions with attendees Poster Schedule Board Assignments Board numbers (B1, B2, B3, LB1, LB2, etc.) indicate the location of the poster board in the Exhibit Hall. Poster numbers (250-Pos, 251-Pos,

Social Events

Opening Reception Hors d’oeuvres and cash bar Dinner Meet-Ups Local attendees available Sunday - Tuesday at 6 PM at the Society Booth to help you explore local restaurants and neighborhoods Monday Evening Reception The place to meet, dance, and socialize with other meeting attendees. Quiet Room with soft music for those who prefer a more quieter atmosphere

Please refer to the programming notice, desktop planner, or mobile app for the date and time of poster presentations.

etc.) correspond with the number assigned to each poster in the online Abstracts Issue.

Presentation Date

Sunday, February 16

Monday, February 17

Tuesday, February 18 Monday after 6 pm Tuesday before 4 pm

Wednesday, February 19 Wednesday after 7 am Wednesday before 3 pm

Setup Time

Saturday after 6 pm

Sunday after 6 pm

Removal Time

Sunday before 5:30 pm

Monday before 5:30 pm

PLEASE NOTE: POSTERS WILL NOT BE COLLECTED OR STORED FOR PICK UP AT A LATER TIME.

Plan the Perfect Day! Meeting Mobile App: • Stay organized and keep up with the latest event information • Search by keyboards, sessions, presentations, or authors • Bookmark session, abstracts, presentations, exhibitors • Create your itinerary • Sync itinerary you may have created using the Desktop Planner into the mobile app • View abstracts • Make and keep notes about sessions • Browse exhibitors • Find attendees and connect with colleagues • Follow social media postings • And much, much more!

Download the App Search Apple App Store or Google Play for “Biophysical Society Events”

For all other device types and all other web browser enabled devices, point your mobile browser to https:/ plan.core-apps.com/bpsam2025.

or Scan

Should you have any questions, contact society@biophysics.org or locate your nearest Biophysical Society Meeting Support Staff.

Table of Contents

Code of Conduct . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . III Los Angeles Convention Center Maps. . . . . . . . . . . . . . . . . . . . . . IV SocietyGovernance..................................... VII General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . VIII Society Committee Meetings Schedule . . . . . . . . . . . . . . . . . . . . . . XI AncillaryMeetings.......................................XI Professional Development & Education Sessions . . . . . . . . . . . . . XII Travel Awards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XIII Friday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Satellite Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Saturday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 SubgroupDinnerSchedule................................ 4 SubgroupMeetings...................................... 5 Bioenergetics, Mitochondria & Metabolism . . . . . . . . . . . . . . . . 5 BiologicalFluorescence................................. 5 Biopolymers in Vivo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 Channels, Receptors, and Transporters . . . . . . . . . . . . . . . . . . . 6 Cryo-EM............................................. 6 Membrane Fusion, Fission, and Traffic . . . . . . . . . . . . . . . . . . . . 6 NanoscaleApproachestoBiology. . . . . . . . . . . . . . . . . . . . . . . . 6 Physical Cell Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 TheoryandComputation............................... 7 Bioengineering........................................ 7 Intrinsically Disordered Proteins . . . . . . . . . . . . . . . . . . . . . . . . . 8 Macromolecular Machines and Assemblies . . . . . . . . . . . . . . . . 8 Mechanobiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 MembraneStructureandFunction.. . . . . . . . . . . . . . . . . . . . . . 9 Membrane Transport . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Motility and Cytoskeleton . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Multicale Genome Organization . . . . . . . . . . . . . . . . . . . . . . . . 10 Single-Molecule Forces, Manipulation, and Visualization . . . . 10 Sunday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Symposia 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Symposia 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24

Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 SRAA Competition 6:00 pm –9:00 pm . . . . . . . . . . . . . . . . . . . . . . 27 (see page 52 for a list of SRAA Participants) Sunday Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28 Monday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 Symposia 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Symposia 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Awards & 2025 Biophysical Society Lecture . . . . . . . . . . . . . . . . . 76 MondayPosters........................................ 77 Tuesday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 Symposium 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . 108 Platforms 10:45 am –12:45 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 Symposium 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 Platforms 4:00 pm –6:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 Workshops 7:30 pm –9:30 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 TuesdayPosters....................................... 117 Wednesday Schedule of Events . . . . . . . . . . . . . . . . . . . . . . . . . 141 Symposia 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 Platforms 8:15 am –10:15 am . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 Symposia 1:00 pm –3:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146 Platforms 1:00 pm –3:00 pm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 WednesdayPosters.................................... 150 Exhibits.............................................. 177 ExhibitorPresentations................................. 178 Exhibitor List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .185 Product Categories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196 Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201

From Clamshells to Clefts: The Molecular Basis of Synaptic Transmission About the Cover Molecule Molecular structures of AMPA, NMDA and kainate receptors.

2025 Biophysical Society Lecturer

Eric Gouaux Vollum Institute, Oregon Health and Science University

List of Advertisers in the 2025 Annual Meeting Program:

Mad City Labs Inc Sutter Instrument

The Biophysical Society would like to thank the following companies for their generous support of the Annual Meeting: APS Physical Review Journals Bruker Burroughs Wellcome Fund Calibre Scientific Carl Zeiss Microscopy LLC Cell Press Chroma Technology

Cube Biotech Depixus SAS Elements srl

Fidabio HORIBA Impetux Optics SL JASCO Journal of General Physiology Leica Microsystems LUMICKS Mad City Labs Inc

Malvern Panalytical Molecular Devices Nanion Technologies Nikon Instruments Inc Nuclera wwPDB Foundation Sophion Bioscience A/S Sutter Instrument Co Thermo Fisher Scientific

As of January 1, 2025

II

Biophysical Society Code of Conduct, Anti-Harassment Policy

The Biophysical Society (BPS) is committed to providing an environment that encourages the free expression and exchange of scientific ideas. As a global, professional Society, the BPS is committed to the philosophy of equal opportunity and respectful treatment for all, regardless of national or ethnic origin, religion or religious belief, gender, gender identity or expression, race, color, age, marital status, sexual orientation, disabilities, veteran status, or any other reason not related to scientific merit. All BPS meetings and BPS-sponsored activities promote an environment that is free of inappropriate behavior and harassment by or toward all attendees and participants of Society events, including speakers, organizers, students, guests, media, exhibitors, staff, vendors, and other suppliers. BPS expects anyone associated with an official BPS-sponsored event to respect the rules and policies of the Society, the venue, the hotels, and the city. Definition of Harassment The term “harassment” includes but is not limited to epithets, unwelcome slurs, jokes, or verbal, graphic or physical conduct relating to an individual’s race, color, religious creed, sex, national origin, ancestry, citizenship status, age, gender or sexual orientation that denigrate or show hostility or aversion toward an individual or group. Sexual harassment refers to unwelcome sexual advances, requests for sexual favors, and other verbal or physical conduct of a sexual nature. Behavior and language that are welcome/acceptable to one person may be unwelcome/ offensive to another. Consequently, individuals must use discretion to ensure that their words and actions communicate respect for others. This is especially important for those in positions of authority since individuals with lower rank or status may be reluctant to express their objections or discomfort regarding unwelcome behavior. It does not refer to occasional compliments of a socially acceptable nature. It refers to behavior that is not welcome, is personally offen sive, debilitates morale, and therefore, interferes with work effectiveness. The following are examples of behavior that, when unwelcome, may constitute sexual harassment: sexual flirtations, advances, or propositions; verbal comments or physical actions of a sexual nature; sexually degrading words used to describe an individual; a display of sexually suggestive objects or pictures; sexually explicit jokes; unnecessary touching. Attendees or participants who are asked to stop engaging in harassing behavior are expected to comply immediately. Anyone who feels harassed is encouraged to immediately inform the alleged harasser that the behavior is unwelcome. In many instances, the person is unaware that their conduct is offensive and when so advised can easily and willingly correct the conduct so that it does not reoccur. Anyone who feels harassed is NOT REQUIRED to address the person believed guilty of inappropriate treatment. If the informal discussion with the alleged harasser is unsuccessful in remedying the problem or if the complainant does not feel comfortable with such an approach, they can report the behavior as detailed below. Reported or suspected occurrences of harassment will be promptly and thoroughly investigated. Following an investigation, BPS will immediately take any necessary and appropriate action. BPS will not permit or condone any acts of retaliation against anyone who files harassment complaints or cooperates in the investigation of same.

Reporting a Violation Violations of this Conduct Policy should be reported immediately. If you feel physically unsafe or believe a crime has been committed, you should report it to the police immediately. To report a violation to BPS: • You may do so in person at the Annual Meeting at the BPS Business Office in the convention center. • You may do so in person to BPS senior staff at Thematic Meetings, BPS Conferences, or other BPS events. • At any time (during or after an event), you can make a report through http://biophysics.ethicspoint.com or via a dedicated hotline (phone numbers listed on the website) which will collect and relay information in a secure and sensitive manner. Reported or suspected occurrences of harassment will be promptly and thoroughly investigated per the procedure detailed below. Following an investigation, BPS will immediately take any necessary and appropriate action. BPS will not permit or condone any acts of retaliation against anyone who files harassment complaints or cooperates in the investigation of same. Investigative Procedure All reports of harassment or sexual harassment will be treated seriously. However, absolute confidentiality cannot be promised nor can it be assured. BPS will conduct an investigation of any complaint of harassment or sexual harassment, which may require limited disclosure of pertinent information to certain parties, including the alleged harasser. Once a complaint of harassment or sexual harassment is received, BPS will begin a prompt and thorough investigation. Please note, if a complaint is filed anonymously, BPS may be severely limited in our ability to follow-up on the allegation. • An impartial investigative committee, consisting of the current President, President-Elect, and Executive Officer will be established. If any of these individuals were to be named in an allegation, they would be excluded from the committee. • The committee will interview the complainant and review the written complaint. If no written complaint exists, one will be requested. • The committee will speak to the alleged offender and present the complaint. • The alleged offender will be given the opportunity to address the complaint, with sufficient time to respond to the evidence and bring his/her own evidence. • If the facts are in dispute, the investigative team may need to interview anyone named as witnesses. • The investigative committee may seek BPS Counsel’s advice. • Once the investigation is complete, the committee will report their findings and make recommendations to the Society Officers. • If the severity of the allegation is high, is a possible repeat offense, or is determined to be beyond BPS’s capacity to assess claims and views on either side, BPS may refer the case to the alleged offender’s home institution (Office of Research Integrity of similar), employer, licensing board, or law enforcement for their investigation and decision. Disciplinary Actions Individuals engaging in behavior prohibited by this policy as well as those making allegations of harassment in bad faith will be subject to disciplinary action. Such actions range from a written warning to ejection from the meeting or activity in question without refund of registration fees, being banned from participating in future Society meetings or Society-sponsored activities, being expelled from membership in the Society, and reporting the behavior to their employer or calling the authorities. In the event that the individual is dissatisfied with the results of the investigation, they may appeal to the President of the Society. Any questions regarding this policy should be directed to the BPS Executive Officer or other Society Officer.

Report a Violation

Scan the QR code to access the reporting form.

III

Los Angeles Convention Center

Level 1

PARKING LOT C West Exhibit Hall Posters and Exhibits Education and Career Fair SRAA Competition

D STREET

CHICK HEARN COURT 11TH STREET

T PARKING LOT

Exhibit Lounge Image Contest

L.A. LIVE WAY

TRUCK RAMP ENTRANCE

EXIT

RAMP DOWN

TRUCK DOCK

FD

NORTH APRON

ENTION CENTER DRIVE

TRUCK BRIDGE

FD

FD

First Aid

West Lobby Registration Society Help Desk Society Booth Publications Booth Coat Check

WEST EXHIBIT HALL

HALL B (SOUTH) PLAZA Gender Inclusive Restrooms

HALL A (NORTH) PLAZA

A

B

FE

102

A

101

PE

PICO BOULEVARD

Meeting Rooms

G

PETREE HALL

GALAXY COURT

FD

K

103

E

C D

FE

104

FE

CONCOURSE (F&B) DOCK

PICO DRIVE

PETREE PLAZA

FE

CONCOURSE PLAZA

SERVICE CORRIDOR

A

G

105

G

WEST LOBBY

150C

153C

CONCOURSE HALL

A

150B

153B

West Lobby Foyer at Entrance First Time Attendee Networking JUST-B JUST-B Networking Hour Undergraduate Poster Award Competition (UPAC)

E

E

E

BUSINESS SERVICE CENTER

152

151

153A

150A

COMPASS CAFE

PE

CONCOURSE FOYER

to HALL elow ll HJ.

E

A

A

CONCOURSE

BPS 2025 Lecture

A

PE

GILBERT LINDSAY DRIVE

OUTH

LOBBY

Concourse Foyer Opening Mixer Speed Networking

GILBERT LINDSAY PLAZA

12TH DRIVE

FIGUEROA STREET

PICO STATION

PAGE 3

IV

Los Angeles Convention Center

Level 2

MEETING ROOMS (300,400, 500 SERIES)–LEVEL TWO

Gender Inclusive Restrooms

Meditation Room

WEST EXHIBIT HALL

A BPSOffice Undergraduate Student Lounge Family Room

B

Meeting Rooms

B

508

B

FE

504 505 506 507

510 512 513

514

A

C

C

Speaker Ready Room

509A

516

517

AG

PE

501A

511A

503

518

501B

511B

502B

502A

515A

515B

519

501C

511C

FE

K

Meeting Rooms

FE

FE

308B Travel Awardee Reception PI to PI Mixer Meet the Editors 308A 307

Meeting Rooms

Meeting Rooms

Meeting Rooms

Meeting Rooms Meeting Rooms

309

306B

SERVICE CORRIDOR

306A

WEST LOBBY

J

FOYER

411 THEATRE

402B

410

405 407

PE

404B 406B

402A

409B

305

304C SOUTH EXHIBIT HALL

403A 403B

408A 408B

401

404A 406A

409A

304B

PE

304A

H

MEETING ROOM CONCOURSE

303B

Meeting Rooms

PE

Meeting Rooms

303A

SOUTH

LOBBY

PE

302

Career Development Center

G

301B

Exhibitor Presentation

Exhibitor Presentation

301A

FE

PAGE 6

PAGE 7

V

VI

Biophysical Society

Biophysical Society

2025 Program Committee

Sudha Chakrapani , Case Western Reserve University, Co-Chair Christopher Yip , University of Toronto, Co-Chair Gilad Haran , Weizmann Institute of Science

Francesca Marassi , Medical College of Wisconsin Joseph Mindell , NINDS, NIH Ibrahim Cissé , Max-Planck Institute of Immunobiology and Epigenetics, 2024 Co-Chair Elizabeth Villa , University of California, San Diego, 2024 Co-Chair

Kumiko Hayashi , Tohoku University Syma Khalid , University of Oxford

BPS Officers

Society Office Staff

Gabriela Popescu , President Lynmarie Thompson , President-elect

Jennifer L. Pesanelli , Executive Officer Erica Bellavia , Meetings Manager Dorothy Chaconas , Director of Meetings & Exhibits Darren Early , Managing Editor Leann Fox , Director of Advocacy & Public Affairs Emma Hedman , Subgroup Program Manager Ally Levine , Senior Sales & Exhibits Manager John Long , Director of Publications Laura Phelan , Communications, Diversity & Belonging Programs Manager

Taekjip Ha , Past President Samantha Harris , Treasurer Teresa Giraldez , Secretary

BPS Council Term Ending 2025 Patricia Bassereau Martin Gruebele Syma Khalid Valeria Vasquez Term Ending 2026 Margaret Cheung Emmanuel Margeat Elizabeth Rhoades Jing Xu Term Ending 2027 Taviare Hawkins Anne Kenworthy Anita Niedziela-Majka Tamar Schlick

Harris Povich , Director of Finance & Operations Saran Ramu , Director of Information Technology Hillary Roegelein , Peer Review Coordinator Caitlin Simpson , Membership Manager Elizabeth Vuong , Director of Marketing, Communications & Outreach Ray Wolfe , Creative Director & IT Systems Engineer Ethan Yosebashvili , Programs Coordinator Umi Zhou , Meetings Manager Meredith Zimmerman , Production Coordinator

Sorting and Programming of 2025 Abstracts Sorting and programming of the 2025 Annual Meeting abstracts into poster and platform sessions was completed by Patricia Bassereau, Manu-Ben Johny, Sudha Chakrapani, Margaret Cheung, Teresa Giraldez, Martin Gruebele, Taekjip Ha, Gilad Haran, Samantha Harris, Taviare Hawkins, Anne Kenworthy, Bill Kobertz, Ilya Levental, Emmanuel Margeat, Joseph Mindell, Ania Niedziela-Majka, David Piston, Gabriela Popescu, Renae Ryan, Tamar Schlick, Jim Sellers, Lynmarie Thompson, Elizabeth Villa, and Jing Xu.

VII

General Information All functions will be held in the Los Angeles Convention Center , unless otherwise noted.

Badges Badges are required for admission to all scientific sessions, including Saturday Subgroup symposia, poster areas, exhibits, and social func tions. A guest badge for non-scientific guests can be purchased for $65 at the on-site registration counter located in the West Lobby. Guest registration is only for admittance to the Opening Mixer on Saturday night and Reception on Monday night. It does not include admission to scientific sessions, posters, or exhibits. There is a $30 fee to reprint a lost or forgotten badge. Banking and Currency Exchange Bank transactions can be done during regular bank business hours at Bank of America, 888 W 7th Street #100, Los Angeles, CA 90017, United States. Please bring two forms of identification with you. Monday–Friday 9:00 AM–5:00 PM Saturday 9:00 AM–4:00 PM Sunday Closed ATM Machines There are six ATM machines located throughout the Center. Two are located in the West Lobby, one is located in the Concourse Corridor next to the Business Center and the remaining three are located in the South Lobby. Business Center, Concourse Corridor The Los Angeles Convention Center provides a full service business cen ter for the convenience of attendees and exhibitors. Services include photocopying, faxing, computer workstations, and printing services. Shipping is provided through UPS. The business center is located in the Concourse Corridor, which joins the West Hall and South Hall. To contact the business center, call (626) 744-1333 or email rkyle@iqcopy. com. Saturday – Wednesday 8:30 AM–5:00 PM Career Development Center, Room 409AB Services are available for both those seeking a position and employers with positions to fill. Please note, the Career Development Center is the only place to post job openings. Unauthorized notices placed elsewhere in the Los Angeles Convention Center will be removed. Saturday 12:00 NOON–6:00 PM Sunday 8:00 AM–6:30 PM Monday–Tuesday 8:00 AM–5:30 PM Certificates of Attendance Certificates of Attendance may be obtained in person at the Society Help Desk located at registration in the West Lobby or in the Society Meeting Office, in Room 509ABC. Code of Conduct The Biophysical Society Annual Meeting provides an environment that encourages free and respectful expression and exchange of scientific ideas. Please review the Code of Conduct policy (page III) that all meet ing participants must follow.

Coat Check/Luggage Storage, West Lobby Please do not bring luggage to meeting rooms. If you are planning to check items, please plan to arrive early to ensure that you are not late for sessions due to long lines. Items will be checked and securely stored during posted hours for a charge of $3.00 per item. Items not picked up at closing will be moved to the Society Meeting Office, Room 509ABC. Saturday 7:30 AM–7:30 PM Sunday–Tuesday 7:30 AM–6:30 PM Wednesday 7:30 AM–4:00 PM Dinner Meet-Ups Interested in making new acquaintances and experiencing the cuisine of Los Angeles? Meet at the Society Booth each evening, Sunday through Tuesday, at 6:00 PM, where a BPS member will coordinate dinner at a local restaurant. Exhibits, West Exhibit Hall The Exhibit Hall features the most advanced equipment, products, services, and publications available. A list of exhibitors as of January 1, 2025, can be found on page 19. Please see Online Addendum for those registered after January 1, 2025. Sunday 10:00 AM–5:00 PM Monday 10:00 AM–5:00 PM Tuesday 10:00 AM–4:00 PM Exhibitor Lounge, West Exhibit Hall Exhibitors may visit the Exhibitor Lounge at the following times for assistance while at the meeting. Friday 8:00 AM–5:00 PM Saturday 8:00 AM–3:00 PM Sunday 8:00 AM–5:00 PM Monday 8:00 AM–5:00 PM Tuesday 8:00 AM–4:00 PM Wednesday Closed Exhibit Hall Bingo Join our participating exhibitors in the Exhibit Hall for a fun and engag ing new game! Pick up a bingo card inside the entrance of the Exhibit Hall. Over three days, collect multicolored dots from exhibitors and put them on the appropriate bingo squares to form three nine-sticker lines. Completed bingo cards will be entered into the Tuesday Exhibitor Raffle drawing for Apple Airpods! You must be present to win. Family Room, Room 507 The Family Room is equipped with diapers, wipes, labels for breast milk, plastic bags for disposing of diapers, electrical outlets for pumps, a small refrigerator, private areas for nursing, and a small area for rest and play. Friday 2:00 PM–5:00 PM Saturday 8:00 AM–7:00 PM Sunday–Tuesday 7:30 AM–10:00 PM Wednesday 8:00 AM–3:00 PM

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Poster Sessions, West Exhibit Hall Sunday–Wednesday

First Aid, West Lobby across from Petree Hall In case of a medical emergency, dial 3000 from any house phone or 213-765-4605. The First Aid room is located outside of Petree Hall. For other minor medical needs, this room will be staffed with First Aid Administrators trained in First Aid Response during the hours below. Saturday 8:00 AM–6:30 PM Sunday 7:30 AM–6:30 PM Monday 7:30 AM–9:00 PM Tuesday 7:30 AM–6:30 PM Wednesday 7:30 AM–3:30 PM Individuals Requiring Assistance Attendees requiring special assistance during the meeting should visit the Society Meeting Office in Room 509ABC. Society staff will do their best to accommodate requests, however, we cannot ensure that spe cial needs will be met without prior notice. Internet Access Wireless Internet access is available free-of-charge in the lobby and common spaces of the Los Angeles Convention Center, excluding the Exhibit Hall and meeting rooms. Lactation Rooms LACC has two private lactation rooms for nursing mothers located in the First Aid Offices in West Hall Lobby (outside Hall A – across from Petree C) and in the South Hall Lobby (main level by Pico Street entrance). Meditation Room, Room 504 A room will be available for attendees to use for quiet meditation or prayer. Saturday–Tuesday 8:00 AM–10:00 PM Wednesday 8:00 AM–3:30 PM Mobile App and Desktop Planner The Biophysical Society’s Official Mobile App is available for download in the App Store and the Google Play Store. iOS and Android Users can search for “Biophysical Society Events” to download the App. We do not support native apps for Windows Mobile; however, those users may access our mobile-friendly Desktop Planner at www.biophysics. org/2025meeting. Using the Mobile App you can view and create schedules, view abstracts/authors/exhibitors, receive event alerts from BPS, join the conversation on social media, find and interact virtually with other attendees, and sync itineraries that were created with the Desktop Planner. Parking The Los Angeles Convention Center includes a parking facility for up to 5,600 vehicles. There are garages at the West and South Halls, as well as parking on Bond Street. The Convention Center also offers parking lot C that is off of L.A. Live Way. Poster Pick Up Posters ordered in advance through Tray Printing will be available for pick up in the West Lobby near the Exhibit Hall during the following hours: Saturday 4:00 PM–7:00 PM Sunday–Tuesday 9:00 AM–11:00 AM and 1:00 PM–4:00 PM No Wednesday Pick Up

The Exhibit Hall will open at 8:00 AM each morning. It will remain open for poster viewing until 10:00 PM each night, except for Tuesday, when it will close at 4:00 PM for safety purposes during exhibit tear down. Posters are arranged according to topic. Your poster board number begins with “B.” On the day of presentation, authors assigned odd-numbered poster boards should present at 1:45 PM–2:45 PM (10:30 AM–11:30 AM on Wednesday); even-numbered posters should present at 2:45 PM–3:45 PM, (11:30 AM–12:30 PM on Wednesday). Other hours, day or evening, may be posted by the authors as desired. Additionally, authors may leave note paper so that visitors may request an appointment. Abstracts submit ted after October 4, 2024, are scheduled each day, Sunday–Wednesday, during the regular poster sessions. These board assignments will begin with “LB.” Posters are to be removed by 5:30 PM on Sunday and Monday, by 4:00 PM on Tuesday to accommodate exhibit teardown, and by 3:00 PM on Wednesday. Please do not leave materials or belongings under poster boards or in the poster area. The Society is not responsible for any articles left in the poster area. Raffles Tuesday Exhibitor Raffle: Want to win Apple Airpods? Join our participating exhibitors in the Exhibit Hall for a fun and engag ing new game! Pick up a bingo card inside the entrance of the Exhibit Hall. Over three days, collect multicolored dots from exhibitors and put them on the appropriate bingo squares to form three nine-sticker lines. Completed bingo cards will be entered into the Tuesday Exhibitor Raffle drawing for Apple Airpods! Prize drawing will be announced in the Exhibit Hall on Tuesday, February 18 at 3:00 PM, you must be present to win. Wednesday Poster Session Raffle: Want to win a Bose Bluetooth Speaker? Attend the Wednesday Poster Sessions in the Exhibit Hall for a chance to win! Every badge comes with a Poster Session ticket. Drop your ticket in the ballot box in the front of the Exhibit Hall. The winner will be announced in the Exhibit Hall on Wednesday, February 19 at 12:30 PM, you must be present to win. Stop by the Society Booth to answer the biophysics trivia question for a chance to win a t-shirt each day Saturday–Tuesday. Registration Hours, West Lobby Friday 3:00 PM–5:00 PM Saturday 7:30 AM–6:30 PM Sunday–Tuesday 7:30 AM–5:00 PM Wednesday 8:00 AM–3:00 PM Restrooms Restrooms are located in the Exhibit Hall, West Lobby, Concourse Foyer, and four banks on the meeting room levels. Gender-inclusive restrooms are located on multiple levels of the Los Angeles Convention Center. Level One: Outside Galaxy Court Level Two: Outside Room 551A

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Social Media Society staff will be updating the social media channels below through out the meeting. Use #bps2025 to join the conversation! Follow us on Follow us on: X: @BiophysicalSoc Bluesky: @biophysicalsoc.bsky.social Facebook: www.facebook.com/biophysicalsociety Instagram: @biophysicalsociety Blog: www.biophysics.org/blog Social Media/Photography Policy The Biophysical Society welcomes the use of social media to share information from the 69th Biophysical Society Annual Meeting and to engage with the biophysics community. Please use the Annual Meeting hashtag #bps2025 when posting to help others follow along. We encourage you to share highlights from the meeting, suggest ses sions to attend, discuss stand-out presentations and posters, and con nect with your fellow biophysicists, as well as our sponsors and exhibi tors. When sharing information about what you see and hear in meeting sessions, please refrain from photographing or sharing full details of the material presented, to respect the intellectual property of the present ers. Some presenters may request, verbally or in writing, that attendees not share information about their presentations and content; please honor those requests so that we can maintain a professional, respectful environment. Presenters: If you do not wish to have your research shared via social media, please make an announcement before and during your pre sentation. BPS strongly encourages compliance with speaker requests regarding social media sharing but cannot guarantee it. Due to the sensitive nature of data and the preliminary, unpublished research find ings, all filming and recording of any kind (camera, cell phones, personal devices) in the scientific session rooms, Exhibit Hall, and poster area are strictly prohibited unless the individual doing the filming or recording is accompanied by a member of the Society staff. Any individual seen taking photographs in any session room, the Exhibit Hall, or poster area will be escorted out by security. Society Meeting Office, Room 509ABC Friday 3:00 PM–5:00 PM Saturday 8:00 AM–6:30 PM Sunday–Tuesday 7:30 AM–5:00 PM Wednesday 8:00 AM–3:00 PM

Speaker Ready Room, Room 503 We highly encourage all presenters in Symposia, Workshops, and Platform sessions to visit the Speaker Ready Room one day before their scheduled presentation time. This room will be set up for your use and will contain several screens and data projectors to allow you the oppor tunity to review your material before your scheduled presentation time slot. All speakers must bring their own laptops. An audiovisual techni cian will be available during room hours to assist you in setting up your laptop with the data projector and answer any questions. As a courtesy to other presenters, please limit your viewing time to five minutes dur ing peak times. Saturday–Tuesday 8:00 AM–6:30 PM Wednesday 8:00 AM–1:00 PM Data projectors will be provided in all session rooms in the Los Angeles Convention Center. The data projectors will be compatible with both Windows and Mac laptops. Speakers must bring their own laptops. The Society does not provide laptops for those with flash drives or other storage devices. Ride Share and Transportation The easiest way to pick up transportation to and from the Los Angeles Convention Center is through ride share services. Local Transportation, UBER and Lyft are accessible in Los Angeles. Undergraduate Student Lounge, Room 508ABC This special space is reserved for undergraduate meeting attendees looking for a place to relax or catch up on coursework they may miss while at the Annual Meeting. Saturday–Tuesday 8:00 AM–6:00 PM Wednesday 8:00 AM–12:00 NOON Water Stations The Los Angeles Convention Center offers filtered water-filling stations and drinking fountains throughout the lobby areas and hallways.

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Governance and Committee Meetings All rooms are located in the Los Angeles Convention Center , unless otherwise noted.

Friday, February 14 3:30 PM–4:30 PM New Council Orientation JW Marriott, Atrium I 5:00 PM–9:00 PM Joint Council Reception, Dinner, and Meeting JW Marriott, Plaza I-II Saturday, February 15 8:00 AM–11:30 AM Joint Council Meeting (continued) JW Marriott, Plaza I-II Sunday, February 16 8:30 AM–10:30 AM CPOW Committee Meeting Room 405 12:00 PM–1:30 PM Public Affairs Committee Meeting Room 405 3:30 PM–5:00 PM Early Careers Committee Meeting Room 405

4:00 PM–6:00 PM Publications Committee Meeting Room 407 7:00 PM–10:30 PM BPS Publications Dinner Mastro's Ocean Club Monday, February 17 8:30 AM–10:30 AM Committee for Inclusion and Diversity Meeting Room 405 11:30 AM–1:30 AM Biophysical Journal Associate Editors Meeting Room 405 3:30 PM–5:30 PM Membership Committee Meeting Room 405 Tuesday, February 18 8:00 AM–9:00 AM Biophysical Society Business Meeting Room 403B

9:00 AM–10:30 AM Subgroup Chairs Meeting Room 518 1:00 PM–3:00 PM The Biophysicist Editorial Board Meeting Room 405 2:00 PM–3:00 PM Committee on Sustainability Meeting Room 518 3:00 PM–5:00 PM Education Committee Meeting Room 407 3:30 PM–5:30 PM Biophysical Reports Editorial Board Meeting Room 405 Wednesday, February 19 8:00 AM–11:30 AM New Council Meeting Room 518

The Biophysical Society would like to thank Society members who serve on Council or Committees for their dedication and efforts.

Ancillary Meetings

SoBLA - Society of Latino American Biophysicists Tuesday, February 18, 8:00 PM - 10:00 PM Room 408B

Korean Biophysicists Meeting Sunday, February 16 5:30 PM - 6:00 PM Room 408A

Mark Your Calendars! Future BPS Annual Meetings 70 th Annual Meeting February 21–25, 2026 San Francisco, California 71 st Annual Meeting February 20–24, 2027 Philadelphia, Pennsylvania 72 nd Annual Meeting February 19–23, 2028 San Diego, California

73 rd Annual Meeting February 17–21, 2029 Los Angeles, California

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Professional Development & Educational Sessions

Monday, February 17, 2025 7:30 AM–8:30 AM

The Society’s committees have planned a variety of professional devel opment activities to take place during the Annual Meeting. Below is a schedule of all of those activities. Detailed descriptions of the sessions can be found in the daily program. In addition, a student lounge for undergraduates will be available available Saturday, February 15, to Wednesday, February 19, in Room 409AB. Sessions in italics will be held in Career Development Center, Room 409B. Saturday, February 15, 2025 3:00 PM–4:00 PM Engaging with Employers at Career Fairs, Info Sessions, Scholarly Meetings and other Similar Opportunities

Graduate Student Breakfast

9:00 AM–10:00 AM Demystifying the Academic Job Search I: Understanding the Search 10:30 AM–11:30 AM Translating Your Credentials: Writing Effective resumes + Cover Letters for Industry, Government, and Nonprofit Jobs 11:00 AM–12:30 PM Annual Meeting of the Student Chapters 12:00 PM–1:00 PM Marketing Your Value: Crafting your Elevator Pitch/30 Second Value Statement/Brand Statement 1:00 PM–2:30 PM Artificial Intelligence Policy in Biomedical Research 1:15 PM-2:15 PM Looking Beyond Academia: Identifying Your Career Options using MyIDP, LinkedIn & More

3:00 PM–5:00 PM

Undergraduate Poster Award Competition

One-on-One Resume and Career Counseling* 2:00 PM–2:40 PM | 4:30 PM–4:50 PM

1:30 PM - 3:30 PM

Hands-on Training: Four Interpretable Machine Learning Techniques to Immediately Accelerate Your Research Current and Future Landscapes of Review and Publishing The Industry Interview: What You Need to Do Before, During, and After to Get the Job Managing It All: Making Time for Success Navigating an International Job Search Biophysics 101: Wearable Technology

Sunday, February 16, 2025 7:30 AM–8:30 AM

1:30 PM–3:00 PM 2:15 PM–3:45 PM

Postdoctoral Breakfast

9:00 AM–10:00 AM Networking for Biophysicists: How to Create Your Dream Career 10:30 AM-11:30 AM What Can You Do with a PhD? A Lot More Than You Might Think 11:30 AM–1:00 PM Undergraduate Student Pizza “Breakfast” 12:00 PM–1:00 PM Public Speaking Masterclass: How to Rock the Podium and Give a Fantastic Talk 1:00 PM–3:00 PM Education and Career Opportunities Fair 1:15 PM-2:15 PM A Novel Approach to Writing NIH-Style Research and Training Applications: Rhetorical Patterns, Storytelling, Verbal Feedback 2:00 PM–4:00 PM Teaching Science Like We Do Science 2:30 PM–3:30 PM The NIH K99/R00 Award – A Unique Award for Postdocs Who Have Demonstrated Readiness for Independence

2:30 PM–3:30 PM

2:30 PM–4:00 PM 4:00 PM–5:00 PM 4:30 PM–6:00 PM 5:00 PM–6:00 PM

Speed Networking

JUST-B Networking Hour One-on-One Resume and Career Counseling* 9:00 AM–1:10 PM | 2:30 PM–4:30 PM | 5:20 PM–6:00 PM

Tuesday, February 18, 2025 9:30 AM–10:30 AM

How to champion yourself – in the lab, at work, in your career

11:30 AM–12:30 PM Demystifying the Academic Job Search II: Preparing your Written Application Materials 12:00 PM–1:30 PM Founding and Establishing a Research Laboratory at a Primarily Undergraduate Institution

2:30 PM–4:00 PM 4:00 PM–5:00 PM 4:00 PM–6:00 PM 5:00 PM–7:00 PM

Sustainability in Scientific Research

Nailing the Job Talk, or Erudition Ain’t Enough

PI to PI Mixer

Primarily Undergraduate Institutions (PUI) Network Annual Meeting Mixer

1:00 PM–2:30 PM 2:00 PM–3:30 PM

Careers in Industry: A Q&A Panel Inside NIH: Explore Biophysics Grant Opportunities in Key Institutes Leveraging LinkedIn in the PhD Job Search: Networking, Informational Interviews, and More Inside Perspectives and Opportunities: NSF Grants - CANCELED

One-on-One Resume and Career Counseling* 9:20 AM–1:00 PM | 2:30 PM–5:40 PM

2:30 PM–3:30 PM

3:30 PM–5:00 PM

One-on-One Resume and Career Counseling* 9:00 AM–12:00 PM | 2:00 PM–3:30 PM | 3:50 PM–5:00 PM

* Slots for the One-on-One Resume and Career Counseling sessions are available on a first-come, first-served basis and fill up quickly. You may sign up for a slot beginning at 12:00 NOON on Saturday, February 15, in the Career Development Center, Room 409A. Please come prepared with resumes, CVs, and other appropriate materials.

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Travel Grant Awardees

Eugenia Guillermina Bravo, IMSaTeD, CONICET-UNSE, Argentina THE LANTHANIDE GADOLINIUM INHIBITS THE ELECTRICAL OSCILLATIONS OF MICROTUBULES. 659-Pos, B443 Alexander Bromley, University of Mississippi, USA ELUCIDATING THE ORIGINS OF TRANSIENT SECONDARY STRUCTURE IN TUBULIN E-HOOKS USING QUANTUM MECHANICS. 658-Pos, B442 David P. Buckley, University of Missouri – Columbia, USA HUMAN INFECTION WITH ENTEROTOXIGENIC E. COLI ELICITS MULTIPLE MODES OF ANTIBODY-MEDIATED INHIBITION OF THE EATA MUCIN DEGRADING PROTEASE. 223-Pos, B7 Alisha Budhathoki, University of Illinois at Chicago, USA IN VIVO SINGLE PARTICLE TRACKING IN DIFFRACTION-SIZED BIOMOLECULAR CONDENSATES. 2717-Pos, B181 ARPAN BYSACK, Saha Institute of Nuclear Physics, India STRUCTURAL DYNAMICS OF THE SLIDE HELIX OF KIRBAC1.1 CHANNEL IS ALTERED IN MICELLES AND MEMBRANES. 2783-Pos, B247 Mehmet Niyazi Çetin, Bahcesehir University Medicine, Turkey INNOVATIVE SURGICAL TECHNOLOGIES FOR UTERUS REPAIR AFTER CESAREAN SECTION. 1589-Pos, B596 Soumya Chandrasekhar, Kent State University, USA STRUCTURE DETERMINATION OF MEMBRANE PROTEINS USING DNA BASED NANODISCS. 2618-Pos, B82 Lexin Chen, University of Florida, USA MDANCE: FLEXIBLE AND VERSATILE N -ARY CLUSTERING PACKAGE. 2311-Pos, B505 Sean J.X. Chen, University of Arizona, USA GPCR SIGNAL TRANSDUCTION AFFECTED BY WATER AND LIPIDS. 925-FlashTalk 2811-Pos, B275 America Chi-Uluac, University of Idaho, USA MOLECULAR MECHANISMS UNDERLYING THE SPECTRAL SHIFT OF ZEBRAFISH CONE OPSINS. 1106-Pos, B113 Hayoung Choi, University of Cambridge, United Kingdom MULTSICALE MODELLING OF REVERSOME-BASED CHROMATIN STRUCTURE. 2734-Pos, B198 Woori Choi, University of California, Davis, USA INVESTIGATING THE MECHANISMS OF SK2 CHANNEL MODULATION FOR ATRIAL FIBRILLATION THERAPY. 2205-Pos, B399

Victor Ayo Adediwura, University of North Carolina at Chapel Hill, USA UNDERSTANDING PEPTIDE BINDING AND CONFORMATIONAL TRANSITIONS IN ADHESION GPCR (ADGRG2). 1108-Pos, B115 Haleh Alimohamadi, University of California, Los Angeles, USA ANTAGONISTIC CURVATURE MECHANISMS OF BCL-2 FAMILY PROTEINS REGULATE MITOCHONDRIAL APOPTOSIS. 1720-Plat Chloe Alston, Howard University, USA STRUCTURE DETERMINATION AND METAL COORDINATION CHEMISTRY OF A SET OF CLOSELY RELATED SMALL ORGANIC MOLECULE IRON CHELATING AGENTS. 1875-Pos, B69 Lauren K. Anderson, University of California, Davis, USA SAME BITS, NEW TRICKS: INVESTIGATING STRUCTURAL AND REGULATORY DIFFERENCES BETWEEN P-REX RHOGEFS. 58-Plat 2559-Pos, B23 Paige Anderson, West Virginia University, USA SINGLE-MOLECULE INSIGHTS INTO KINESIN-2 MOTILITY AND ITS ROLE IN CILIOPATHIES. 2259-Pos, B453 Agustina Bacelo, St. John’s University, USA PREDICTED FUNCTIONALITY OF DESIGNED NEURAMINIC ACID SENSING CHIMERIC PROTEINS. 1027-Pos, B34 Toheeb Balogun, University of California, San Diego, USA CHARACTERIZATION OF BAT CORONAVIRUS SPIKE GLYCOPROTEIN DYNAMICS VIA MOLECULAR DYNAMICS SIMULATIONS. 884-FlashTalk 2591-Pos, B55 Joseph D. Barritt, Imperial College London, United Kingdom PHAGE TAIL DEPOLYMERASE N-TERMINAL FLEXIBILITY AIDS BIOFILM BREAKDOWN IN KLEBSIELLA PNEUMONIAE. 2556-Pos, B20 Zoe M. Beris SIMULATION OF PRESSURE DEPENDENT OSMOTIC COEFFICIENTS. 496-Pos, B280 Vladimir Bogdanov, The Ohio State University, USA SPATIAL COMPARTMENTALIZATION OF EXPRESSION OF THE CAM GENES SUPPORTS VERSATILE CA²⁺-CAM SIGNALING IN CARDIAC MYOCYTES. 527-Pos, B311 Sachiko Bower, Bryn Mawr College, USA MOLECULAR DYNAMICS INVESTIGATION OF MEMBRANE PROTEIN FUNCTION. 1915-Pos, B109 Matthew Braga, University of California, Davis, USA BEYOND THE CORE: INVESTIGATING HOW ACCESSORY REGIONS OF PDZ-RHOGEF REGULATE ITS CATALYTIC CORE IN RHOA ACTIVATION. 229-Pos, B13

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