BPS2025 Full Program

1075-Pos Board B82 IN SILICO SCREENING TO TARGET CALPAIN HETERODIMERIZATION WITH SMALL MOLECULES: POTENTIAL DRUGS TO MODULATE CALPAIN ACTIV ITY. Pitambar Poudel , Ivan Shapovalov, Shailesh Kumar Panday, Peter A. Greer, Emil Alexov 1076-Pos Board B83 COMPARATIVE MOLECULAR MODELING AND SIMULATIONS OF BETA ADRENERGIC RECEPTOR-DRUG INTERACTIONS. Kyle C. Rouen , Nancy Daoud, Yanxiao Han, Igor Vorobyov Protein Assemblies II (Boards B84 - B99) 1077-Pos Board B84 EPHA2 RECEPTOR TYROSINE KINASE INTERACTS WITH EPHRINA1 IN CIS THROUGH LIGAND BINDING DOMAIN. Soyeon Kim , Paul Toth, Bing Cheng Wang, Xiaojun Shi 1078-Pos Board B85 STRUCTURAL INSIGHTS INTO THE REGULATION OF A BACTERIAL TYROSINE KINASE BY ITS COUNTERACTING PHOSPHATASE. Sebastien Board B86 STRUCTURES AND PH-DEPENDENT DIMERIZATION OF THE SEVENLESS RECEPTOR TYROSINE KINASE. Gabriele Cerutti , Ronald Arias, Fabiana Bahna, Seetha Mannepalli, Phinikoula S. Katsamba, Goran Ahlsen, Brian Kloss, Renato Bruni, Andrew Tomlinson, Lawrence Shapiro 1080-Pos Board B87 UNDERSTANDING AUTOPHAGIC LYSOSOME REFORMATION: STRUC TURAL INSIGHTS INTO THE AP5:SPG11-SPG15 COMPLEX. Xinyi Mai, Yang Wang, Xi Wang, Ming Liu, Fei Teng, Zheng Liu, Ming-Yuan Su, Goran Stjepanovic 1081-Pos Board B88 UNDERSTANDING SORTASE-PILIN RECOGNITION IN GRAM-POSITIVE BACTERIA. Nicole A. Cheung 1082-Pos Board B89 PH-INDUCED ARC CAPSID DISASSEMBLY IN DROSOPHILA REVEALS KEY STEPS IN INTERNEURONAL COMMUNICATION. Balázs Fábián , Kaelan R. Sullivan, Monika Fuxreiter, Jason D. Shepherd, Gerhard Hummer 1083-Pos Board B90 P-CADHERIN BINDS TO DESMOGLEIN IN A TRANS STRAND-SWAP DIMER CONFROMATION AND FACILITATES DESMOSOME ASSEMBLY. Shipeng Xu , Bin Xie, Sanjeevi Sivasankar 1084-Pos Board B91 SURFACE DELIVERY QUANTIFICATION REVEALS DISTINCT TRAFFICKING EFFICIENCIES AMONG CLUSTERED PROTOCADHERIN ISOFORMS. Elizabeth May , Rachelle Gaudet 1085-Pos Board B92 MONITORING AAA-ATPASE-MEDIATED RIBOSOME ASSEMBLY IN SAC CHAROMYCES CEREVISIAE WITH PIE-FRET IMAGING. Alexandria N. Kerr , Kanda Borgognoni, Olive Hsu, Robin Stanley, Sharonda J. LeBlanc 1086-Pos Board B93 THERMAL REGULATION OF INNATE IMMUNE SIGNALOSOME NUCLE ATION- IMPLICATIONS FOR A NEW FUNCTION OF FEVER. Wenhao Song , Shriram Venkatesan, Randal Halfmann 1087-Pos Board B94 CHARACTERIZATION OF THE MOLECULAR RECOGNITION OF UBIQUITIN BY A DEUBIQUITINATING PROTEASE ELAD. Lubhanshi Garg , Aditya Shriv astava, Sri Rama Koti Ainavarapu Alphonse 1079-Pos

1088-Pos Board B95 THE EFFECT OF THE SICKLE CELL TREATMENT VOXELOTOR ON METHE MOGLOBIN STABILITY AND AGGREGATION. Michael de la Cueva Tamanaha , Brandon Cove, Aldo J. Munoz, Li Xing, Melanie J. Cocco 1089-Pos Board B96 FREE ENERGY LANDSCAPE OF COLLAGEN TRIPLE HELIX ASSOCIA TION. George A. Pantelopulos , Robert B. Best 1090-Pos Board B97 ALTERING TERMINAL LOCATIONS TO MODIFY THE MS2 VLP WITH CIR CULAR PERMUTATION. Shiqi Liang , Danielle Tullman-Ercek 1091-Pos Board B98 OSCILLATORY MECHANISM OF THE CYANOBACTERIAL CIRCADIAN CLOCK. Andy LiWang 1092-Pos Board B99 A SYSTEMS-LEVEL UNDERSTANDING OF CLOSTRIDIUM THERMOCEL LUM’S CELLULOSOME FOR ENHANCED BIOFUEL PRODUCTION. Christine Minor Membrane Protein Dynamics I (Boards B100 - B126) 1093-Pos Board B100 WATER BRIDGING AND LIPIDS WITH UNUSUAL GEOMETRIES STABILIZE PH-DEPENDENT MEMBRANE PORES. Ana-Nicoleta Bondar , Kalina Hris tova, William C. Wimley 1094-Pos Board B101 TARGETING HIDDEN RECEPTOR CONFORMATIONS TO DESIGN SUBTYPE SELECTIVE DRUGS. Carl-Mikael Suomivuori , Ron O. Dror 1095-Pos Board B102 THE VOLTAGE DEPENDENT ANION CHANNEL IS A FLEXIBLE BARREL. Lucie A. Bergdoll , Matthias Elgeti, Michael T. Lerch, Maria Queralt Martin, Jean-Pierre Duneau, Tatiana K. Rostovtseva, Wayne L. Hubbell, Jeff Abramson 1096-Pos Board B103 REAL-TIME OBSERVATION OF LIGHT-INDUCED DYNAMICS OF LH1-RC COMPLEX USING THE DIFFRACTED X-RAY TRACKING METHOD. Tatsunari Ohkubo , Kazuhiro Mio, Hiroshi Sekiguchi, Yuji C. Sasaki 1097-Pos Board B104 BIDIRECTIONAL COMMUNICATION BETWEEN NUCLEOTIDE AND SUB STRATE BINDING SITES IN AN ABC TRANSPORTER MEDIATED BY A CON SERVED INTERDOMAIN SIGNALLING RELAY. Victor Hugo Perez Carrillo, Hannes Neuweiler, Cedric Orelle, Jean-Michel Jault, Ute A. Hellmich 1098-Pos Board B105 THE DISORDERED ISOFORM-SPECIFIC N-TERMINAL DOMAIN OF BRAF KINASE IS CRITICAL FOR REGULATORY AUTOINHIBITION OF RECRUIT MENT TO THE LIPID MEMBRANE. Julian D. Grim , Vasili Revazishvili, Alexia Morales, Youngkwang Lee 1099-Pos Board B106 QUANTITATIVE IMAGING OF VESICLES, MEMBRANE PROTEINS, AND THEIR INTERACTIONS. Minkwon Cha, Sang Hyeok Jeong , Jaehun Jung, Jaehyeon Shin, Min Ju Shon 1100-Pos Board B107 INVESTIGATION OF THE EARLY ACTIVATION STAGE OF CHR2 USING MOLECULAR DYNAMICS SIMULATIONS. Kenta Shobu , Yoshinori Hirano, Kenji Yasuoka 1101-Pos Board B108 STEPWISE ASSEMBLY OF THE PTH-PTH1R-Β-ARRESTIN COMPLEX THROUGH SEQUENTIAL COLLISIONS AT CLATHRIN-COATED PITS. Jonathan E. Pacheco , Karina Peña, Sofya Savransky, Jonh Janetzko, Jean-Pierre Vilardaga

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