BPS2025 Full Program

1551-Pos Board B558 DEVELOPING MULTI-TARGET COMPOUNDS AGAINST OXIDATIVE STRESS AND TAU AGGREGATION FOR ALZHEIMER’S USING MACHINE LEARNING AND PHYSICS-BASED MODELS. Luthary Segura , Elaine Zhao, Vincent Blay Rogers, Donald Sikazwe, Rafael Flores, Kwan Hon K. Cheng 1552-Pos Board B559 DISSECTING THE PATHWAYS AND MECHANISMS OF DRUG RESISTANCE EVOLUTION IN HIV. Avik Biswas , Indrani Choudhuri, Min Li, Zelin Shan, Allan Haldane, Robert Craigie, Ronald M. Levy, Dmitry Lyumkis 1553-Pos Board B560 USING MULTISCALE ONE-DIMENSIONAL CONVOLUTIONAL NEURAL NET WORK FOR THE RAMAN SPECTRAL CLASSIFICATION OF BIOMOLECULES AND MODEL VISUALIZATION. CHE-LUN CHIN , Chia-En Chang, Ling Chao 1554-Pos Board B561 EPISTATIC MODELS AND LATENT GENERATIVE LANDSCAPES DISTIN GUISH PROTEINS WITH FAVORABLE IN VIVO ANTIBIOTIC FUNCTION ALITY. Sophia Alvarez , Charisse M. Nartey, Jose A. De la Paz, Nicholas Mercado, Alyssa Trasporto, Vladimir Volobouev, Faruck Morcos 1555-Pos Board B562 EFFECT OF MEMBRANE COMPOSITION ON IRE1 DIMERIZATION QUAN TITATIVELY EXPOSED BY MACHINE LEARNING-ENHANCED PATH SAM PLING SIMULATIONS. Gianmarco Lazzeri , Emil Jackel, Roberto Covino 1556-Pos Board B563 INTERPRETABLE REPRESENTATION LEARNING FOR 3D MULTI-PIECE INTRACELLULAR STRUCTURES IN HUMAN INDUCED PLURIPOTENT STEM CELLS USING POINT CLOUDS. Ritvik Vasan , Alexandra Ferrante, Antoine Borensztejn, Christopher L. Frick, Nathalie Gaudreault, Saurabh S. Mo gre, Benjamin Morris, Guilherme Pires, . Allen Institute for Cell Science, Susanne M. Rafelski, Julie A. Theriot, Matheus Palhares Viana Optical Microscopy and Superresolution Imaging II (Boards B564 - B592) 1557-Pos Board B564 ADVANCED FLIM AND ISM-FLIM ANALYSIS OPTIONS WITH FLEXIBLE ROI HANDLING. Isabel Gross , Felix Koberling, Evangelos Sisamakis, Ellen Schmeyer, Kamil Bobowski, Marcus Sackrow, Markus Goetz, Matthias Patting, Stefan Eilers, Fabian Jolmes, Rainer Erdmann 1558-Pos Board B565 UNIQUE SPATIAL DEPENDENCE OF AMPAR SUBUNIT CLUSTERS RE VEALED THROUGH QPAINT. Gloria W. Lau , Max Winga, Dirgh Shah, Timothy James Tan, Nicholas Wu, Hee Jung Chung, Paul R. Selvin 1559-Pos Board B566 THE HEAD DOMAIN OF DESMOPLAKIN MODULATES DESMOSOME ARCHITECTURE. Collin Ainslie , Krishna A. Patel, Thi Bao Yen Tran, Alexa L. Mattheyses 1560-Pos Board B567 FRETSAEL - NANOMETER LOCALIZATION OF BIOMOLECULAR INTERAC TIONS USING FLUORESCENCE LIFETIME IMAGING. Yair Razvag , Paz Drori, Eitan Lerner 1561-Pos Board B568 THE T4 VIRUS AS AN IDEAL 3D-BIO-NANORULER FOR SUPER-RESOLU TION MICROSCOPY. Jose I. Gallea , Oleksii Nevskyi, Zuzanna Kaźmierczak, Tao Chen, Paulina Miernikiewicz, Ivan Gligonov, Anna Chizhik, Lenny Reinkensmeier, Krystyna Dąbrowska, Mark Bates, Joerg Enderlein 1562-Pos Board B569 PHASORPY: AN OPEN-SOURCE PYTHON LIBRARY FOR THE ANALYSIS OF FLUORESCENCE LIFETIME AND HYPERSPECTRAL IMAGES USING THE PHASOR APPROACH. Bruno Pannunzio, Bruno Schuty Teske, Michelle A. Digman, Christoph Gohlke, Leonel S. Malacrida

1563-Pos Board B570 SINGLE-MOLECULE FLUORESCENCE ASSAY FOR ANTIBODY-ANTIBODY INTERACTIONS. Katelyn Canedo , Jiah Kim, Daniel Park, Abdullah Husain, Kyu Young Han 1564-Pos Board B571 QUANTIFYING CHROMATIN COMPACTION FROM IMAGING AT LOW PHOTON COUNTS BY CV-ICS. Luca Lanzano’ , Greta Paterno, Silvia Scalisi, Elisa Longo 1565-Pos Board B572 EPIDERMAL DIFFERENTIATION AS REVEALED BY MULTIPHOTON MI CROSCOPY WITH FLUORESCENCE LIFETIME IMAGING - METHODOLOGI CAL INSIGHTS. Chen Qian , Monika Malak, Hongjian Chen, Jeemol James, Syam Nair, Julie Grantham, Marica B. Ericson 1566-Pos Board B573 BEYOND THE EMCCD: THE NEXT GENERATION OF LIVE-CELL BIOLUMI NESCENCE MICROSCOPY. Jian Cui 1567-Pos Board B574 SIMPLIFIED WHOLE-CELL SINGLE-MOLECULE SUPER-RESOLUTION IM AGING IN 3D WITH LONG AXIAL-RANGE DOUBLE-HELIX POINT SPREAD FUNCTIONS. Yuya Nakatani , Scott Gaumer, Yoav Shechtman, Anna-Karin Gustavsson 1568-Pos Board B575 OPTIMAL SEPARATION MEASUREMENT FOR TWO FREELY ROTATING DIPOLE EMITTERS. Sheng Liu , Sujeet Pani, Francisco E. Becerra, Keith A. Lidke 1569-Pos Board B576 FLIM WITH FAST, RIGOROUS CONFIDENCE LIMITS ON LIFETIMES, AMPLITUDES AND PHASORS. Nikhil Mattu , Siem Yonas, Yuyi Liu, Hailey Parry, Brian Glancy, Shureed Qazi, Ayman Slamani, Greg Alspaugh, Dan Sackett, Katie Link, Rozhin Penjweini, Christian A. Combs, Jay R. Knutson 1570-Pos Board B577 RESOLVING INTRACELLULAR DYNAMICS THROUGH TEMPORAL LOCAL IZATION INFERENCE OF SINGLE MOLECULE EMISSION SEQUENCE NET WORKS (TIMENET). Yue Zheng , Li Fang, Maryam Mahmoodi, Hao-Cheng Gao, Cheng Bi, Fang Huang 1571-Pos Board B578 ULTRAFAST FLUORESCENCE LIFETIMES OF NADH VIA FLIM. Katie A. Link , Rozhin Penjweini, Jay R. Knutson 1572-Pos Board B579 FROM PHOTONS TO POSTERIORS: BAYESIAN SINGLE-MOLECULE ANALY SIS WITH FITSA. Hamed Karimi, Martin Laasmaa, Margus Pihlak, Marko Travel Award Winner CHOLESTEROL-ENRICHED NANODOMAINS ANALYSIS BY SINGLE MOL ECULE LOCALIZATION MICROSCOPY OF THE TRANSIENT FORMATION AND DETECTION OF BODIPY-CHOLESTEROL RED-SHIFTED DIMERS IN THE PLASMA MEMBRANE OF MOUSE SPERM. David Torres-Hernandez , Jose Luis De La Vega Beltran, Alberto Darszon Israel, Adan O. Guerrero Cardenas, Chris Wood 1574-Pos Board B581 DNA BASE-STACKING ENABLES PROTEIN PROXIMITY DETECTION AND MULTIPLEXED SUPER-RESOLUTION IMAGING. Abhinav Banerjee , Ve danth Shree Vidwath, Micky Anand, Mahipal Ganji 1575-Pos Board B582 OVERLAPPING NUCLEAR IMPORT AND EXPORT PATHS UNVEILED BY TWO-COLOR MINFLUX. Abhishek Sau , Sebastian Schnorrenberg, Ankith Sharma, Debolina Bandyopadhyay, Ziqiang Huang, Clara Marie Gürth, Sandeep Dave, Siegfried M. Musser Vendelin 1573-Pos Board B580

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