BPS2025 Full Program

Registration/Information 7:30 am - 5:00 pm, West Lobby Biophysical Society Business Meeting 8:00 am - 9:00 am, Room 403B Poster Viewing 8:00 am - 4:00 pm, West Exhibit Hall Symposium Membrane Asymmetry - Biogenesis, Mechanics, and Regulation 8:15 am - 10:15 am, Petree Hall C Chair Sarah Veatch, University of Michigan, USA 1601-Symp 8:15 am MOLECULAR DETERMINANTS AND CELLULAR CONSEQUENCES OF INTERLEAFLET LIPID DISTRIBUTION IN THE PLASMA MEMBRANE. Milka 8:40 am POWER OF MEMBRANE ASYMMETRY: DO PROTEINS RULE LIPIDS OR LIPIDS RULE PROTEINS. Mikhail Bogdanov 1603-Symp 9:05 am MORPHOLOGY AND STABILITY OF ASYMMETRIC MEMBRANES. Rumiana Dimova 1604-SympSelect 9:30 am DYNAMIC REGULATION OF MEMBRANE LIPID ASYMMETRY: MECHA NISMS, MOLECULAR TOOLS, AND PHYSIOLOGICAL FUNCTIONS. Augus tus Lowry, Pengfei Liang, Yang Zhang, Huanghe Yang 1605-Symp 9:50 am PROTEIN PREWETTING AS A PROBE OF PLASMA MEMBRANE STRUC TURE AND FUNCTION. Yousef Bagheri, Mason Rouches, Benjamin B. Machta, Sarah Veatch Symposium Viral Assembly and Pathways for Host Cell Interaction 8:15 am - 10:15 am, Petree Hall D Chair Roya Zandi, University of California, Riverside, USA No Abstract 8:15 am STRUCTURE AND FUNCTIONS OF THE HIV-1 CAPSID: NEW INSIGHTS ON CAPSID REMODELING MECHANISMS. Owen Pornillos No Abstract 8:40 am STRUCTURAL ANALYSIS OF HIV-1 CAPSID DISRUPTION BY LENACAPAVIR USING CRYO-EM. Rob Dick 1606-Symp 9:05 am REPLICATION ORGANELLES OF ARBOVIRUSES THROUGH THE LENS OF A CRYO-ELECTRON MICROSCOPE. Selma Dahmane, Timothee Laurent, Erin Schexnaydre, Jianguo Zhang, Nunya Chotiwan, Bina Kumari Singh, Wai-Lok Yau, Richard Lundmark, Benjamin A. Barad, Danielle A. Grot jahn, Susanne Liese, Andreas Carlson, Anna Overby, Lars-Anders Carlson Doktorova 1602-Symp

1607-SympSelect 9:30 am CONFORMATIONAL FLEXIBILITY AND BINDING MECHANISM OF SARS COV-2 SPIKE VARIANTS. Rong Zhu, Sarah Stainer, Manuel Reithofer, Mateusz Sikora, Daniel Canena, Hannah Seferovic, Lisa Hain, Elisabeth Laurent, Vanessa Monteil, Ali Mirazimi, Yoo Jin Oh, Josef M. Penninger, Gerhard Hummer, Miriam Klausberger, Peter Hinterdorfer 1608-Symp 9:50 am SWITCHABLE CONFORMATIONS IN PROTEIN SUBUNITS: INSIGHTS INTO ICOSAHEDRAL VIRUS ASSEMBLY DYNAMICS. Roya Zandi , Guillaume Tresset, Siyu Li Platform Protein Dynamics and Allostery II 8:15 am - 10:15 am, Room 515A Co-Chairs Cecile Fradin, McMaster University, Canada Anupam Ojha, Flatiron Institute, USA 1609-Plat 8:15 am CREATING 3D MOVIES FROM 2D CRYO-EM SNAPSHOTS OF BIOLOGICAL MOLECULES: BRIDGING DEEP LEARNING-BASED CRYO-EM IMAGE ANAL YSIS WITH MOLECULAR SIMULATION FOR PROTEIN CONFORMATIONAL DYNAMICS. Anupam A. Ojha , Sonya M. Hanson, Rommie E. Amaro 1610-Plat 8:30 am REVEALING SITE-SPECIFIC THERMAL NETWORKS IN OMP-DECARBOX YLASE: DRIVERS OF ENTHALPIC BARRIER CROSSING AND CATALYSIS. Pankaj Dubey , Anish Somani, Jessica Lin, Anthony T. Iavarone, Judith P. Klinman 1611-Plat 8:45 am PRESSURE ADAPTATION AND ELECTROSTATIC DIVERGENCE IN DEEP-SEA EXONUCLEASES. Tejaswi Naidu Koduru , Catherine A. Royer 1612-Plat 9:00 am DYNAMICS OF EXTREMOPHILE PROTEINS. Stephen P. Cramer 1613-Plat 9:15 am DYNAMICS AND COMMUNICATION OF MULTIDOMAIN STEROID RECEP TORS REVEALED THROUGH ACCELERATED AND NONEQUILIBRIUM MO LECULAR DYNAMICS SIMULATIONS. Jordan A. Wenning , Denise Okafor 1614-Plat 9:30 am A MULTISCALE APPROACH TO INVESTIGATING EGFR PATHWAY DYNAM ICS IN LUNG CANCER. Hayate Takagishi, Ai Shinobu , Noriaki Okimoto, Makoto Taiji, Mariko Okada 1615-Plat 9:45 am QUANTITATIVE INTERPRETATION OF FRAP EXPERIMENTS IN HELICAL BACTERIA. Shariful Sakib, Alex Verbeem, Cécile Fradin 1616-FlashTalk 10:00 am INTEGRATIVE HDX: FROM POST HOC ENSEMBLE REWEIGHTING TO HDX MS GUIDED ENHANCED SAMPLING MD SIMULATIONS. Juliet O. Obi, Ally K. Smith, Kyle C. Kihn, Daniel J. Deredge 1617-FlashTalk 10:05 am STRUCTURAL CONTEXT OF THE UEV DOMAIN, TSG101 AND BEYOND. David Nyenhuis , Jose Vazquez, Nico Tjandra 1618-FlashTalk 10:10 am STRUCTURAL FLUCTUATIONS OF HUMAN CALMODULIN AT LOW CAL CIUM SATURATIONS. Karoly Liliom , Gusztav Schay, Gergely Burkódi, J Michael Klopf, Laszlo Smeller, Franci Merzel, Miklós Kellermayer, Erika Balog

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