BPS2025 Full Program

1938-Pos Board B132 DECHIPERING THE MECHANISM OF PROTEIN AGGREGATION AND EFFECTS OF IN-HIBITORS USING SINGLE-MOLECULE MASS PHOTOM ETRY. Aaron Lyons , Simanta S. Paul, Allan Yarahmady, Sue-Ann Mok, Michael T. Woodside 1939-Pos Board B133 A BACKGROUND ENZYMATIC ACTIVE BATH AFFECTS LIQUID-LIQUID PHASE SEPARATION OF PROTEINS. Kevin Ching , Jennifer Schwarz, Jen nifer L. Ross 1940-Pos Board B134 THE INTERPLAY OF SYSTEM COMPOSITION, CHAIN LENGTH, AND SE QUENCE ON MATERIAL AND ORGANIZATIONAL PROPERTIES OF PEPTIDE CONDENSATES. William Brown 1941-Pos Board B135 Travel Award Winner A NATURAL POLYPHENOL MYRICETIN AS AN INHIBITOR OF SOD1 AG GREGATION IN ALS NEURODEGENERATIVE DISEASE. Vijay R. Tomar 1942-Pos Board B136 THE ROLE OF TAU-POLYANION INTERACTIONS IN TAU FIBRIL STABILIZA TION. Fiona Mon , John E. Straub 1943-Pos Board B137 MAPPING OF THE MOLECULAR ARCHITECTURE OF PATHOLOGICAL PROTEIN DEPOSITS IN ALZHEIMER’S DISEASE. Prakash Nepal, Abdullah Al Bashit, Theresa R.C. Stewart, Bradley T. Hyman, Lee Makowski 1944-Pos Board B138 AΒ42 ACCELERATES PATHOGENIC STRUCTURAL TRANSFORMATION WITHIN THE AMYLOIDOGENIC CORE REGION OF TDP-43. Adam J. Gatch , Feng Ding 1945-Pos Board B139 ANALYSIS OF CATION-STABILIZED HYPF-N OLIGOMERS TO STUDY THE STRUCTURAL DETERMINANTS OF PROTEIN MISFOLDED OLIGOMER TOXICITY. Julia C. Palchak , Alyssa R. Cornell, Mary Claire Schleck, Silvia Errico, Benedetta Mannini, Fabrizio Chiti, Lucas B. Fallot, Ryan Limbocker 1946-Pos Board B140 ON THE USE OF AMINOSTEROLS TO TARGET PROTEIN DEPOSITION IN ALZHEIMER’S AND PARKINSON’S DISEASES. Ryan Limbocker , Lucas B. Fallot 1947-Pos Board B141 CONCENTRATION-DEPENDENT ROLE OF APOLIPOPROTEIN E IN AMY LOID BETA CLEARANCE BY HUMAN ASTROCYTES. Kamila Nurmakova , Zachary Levine 1948-Pos Board B142 DYNAMIC HUNTINGTIN OLIGOMERS AS TOXIC SPECIES AND TARGETING THEM AS A THERAPEUTIC STRATEGY. Justin A. Legleiter 1949-Pos Board B143 PROTEIN-MEMBRANE INTERACTIONS IN CELL-TO-CELL TRANSMISSION OF INTRINSICALLY DISORDERED PROTEINS. Nora Jaber , Sanjna Sharma, Yun-Kyung Lee, Wei Dai 1950-Pos Board B144 MEMBRANE-ASSISTED FIBRIL FORMATION OF Α-SYNUCLEIN. Matthew MacAinsh , Fidha Nazreen Kunnath Muhammedkutty, Huan-Xiang Zhou 1951-Pos Board B145 A MATHEMATICAL MODEL TO QUANTIFY TAU AGGREGATION RATES AND DETERMINE MOLECULAR MECHANISMS FROM PATIENT DATA. Georg Meisl , Shih-Huan Huang, Annelies Quaegebeur, Timothy Rittman, Mattthew Cotton, James Rowe, Tuomas P. Knowles, David Klenerman

1952-Pos Board B146 DEVELOPING A COMPUTATIONAL WORKFLOW WITH STATIC, DYNAMIC, AND MACHINE LEARNING METHODS TO GUIDE ANTIBODY FORMULA TION DEVELOPMENT. Andrew H. Beaven , Stuart W.J. Ember, Jing Yu, Maral Adeli-Koudehi, Lisa Hughes, Glenn M. Ferreira 1953-Pos Board B147 INHIBITION OF IAPP FIBRIL EXTENSION AND RETENTION OF RECEPTOR FUNCTION BY NOVEL IAPP ANALOGS: A COMPUTATIONAL STUDY. Ashish Kumar K. Agrahari , Feng Ding 1954-Pos Board B148 INTERACTIONS OF NANOPARTICLES WITH SELECTED AMYLOIDOGENIC PROTEINS. Maciej Kozak , Karolina Rucinska, Joanna Maksim, Michał Taube, Daria Wojciechowska, Ahmet Kertmen 1955-Pos Board B149 UNDERSTANDING PROTEIN SELF-ASSEMBLY USING AN INTEGRATIVE ANTIBODY-DISCOVERY APPROACH. Devkee M. Vadukul, Dimitra Gi alama, Ying Ge, Rebecca J. Thrush, Giacomo Corucci, Sheena E. Radford, Francesco A. Aprile 1956-Pos Board B150 TRANSTHYRETIN AGGREGATION IN FLUID FLOW - A STRUCTURAL PER SPECTIVE. Irina Ritsch , Peter E. Wright, Jane Dyson 1957-Pos Board B151 LIVE CELL IMAGING OF INFLAMMATION INDUCED BY PROTEIN AGGRE GATES. Arpan Dey , Yuhao Cui, Joseph P. Boyle, Prasanna Suresh, Clare Bryant, David Klenerman 1958-Pos Board B152 QUANTITATIVE BOND-SELECTIVE IMAGING OF POLYQ AGGREGATES WITHOUT EGFP LABELING REVEALS AGGREGATION COMPARTMENTAL IZATION AND GROWTH DYNAMICS IN LIVE NEURONS. Xiaotian Bi , Li-En Lin, Lu Wei 1959-Pos Board B153 INFERENCE FOR FIBRIL TOPOLOGY USING NETWORK HAMILTONIAN MODELS. Zixiao Zong, Elizabeth M. Diessner, Carter T. Butts 1960-Pos Board B154 DECOUPLING THE ROLE OF DNA ON MUTANT P53 AGGREGATION. Matthew Steinsaltz , Zachary A. Levine 1961-Pos Board B155 FLAT CLATHRIN LATTICES RESULT FROM KINETIC TRAPPING IN RE SPONSE TO GROWTH FACTOR STIMULUS. Lingxia Qiao , Marco Alfonzo Mendez, Justin W. Taraska, Padmini Rangamani Condensates: Physical Properties and Modeling III (Boards B156 - B188) 1962-Pos Board B156 SINGLE MOLECULE INVESTIGATION OF LIQUID-LIQUID AND LIQUID SOLID PHASE SEPARATION OF AMYLOID PROTEINS. Mahaprasad Sahu, Jiapeng Wei, Vinoth K. V, Tuomas P. Knowles, Kanchan Garai 1963-Pos Board B157 COMPLEX DNA EFFECTS ON POLYPHOSPHATE CONDENSATE GROWTH AND ARCHITECTURE. Jenna K.A. Tom , Ravi Chawla, Tumara Boyd, Nicho las H. Tu, Tanxi Bai, Danielle A. Grotjahn, Donghyun Park, Lisa R. Racki, Ashok Deniz 1964-Pos Board B158 TURBOCHARGED CARBON FIXATION: A PREDICTIVE COMBINATORIAL MODEL FOR SELF-ASSEMBLY AND CONDENSATION OF RUBISCO. Alex L. Payne-Dwyer , Gaurav Kumar, James Barrett, Laura Gherman, Michael Hodgkinson, Michael Plevin, Luke Mackinder, Mark C. Leake, Charley Schaefer

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