BPS2025 Full Program

Platform Membrane Structure 1:00 pm - 3:00 pm, Room 501ABC

Platform Membrane Receptors and Signal Transduction 1:00 pm - 3:00 pm, Room 511ABC Co-Chairs Maria Falzone, University of Texas Health Science Center, USA Alberto Gonzalez-Hernandez, Weill Cornell Medicine, USA 2527-Plat 1:00 pm MITOCHONDRIA-ASSOCIATED RESTRICTED SPACES REGULATE COM PARTMENTALIZED CAMP SIGNALING IN VENTRICULAR MYOCYTES IN HEALTH AND DISEASE. María P. Saldías Maulén , Nisha Chouhan, Andrea B. Agarwal, Shailesh R. Agarwal 2528-Plat 1:15 pm SWEET TASTE RECEPTOR ACTIVATION REGULATES CALCIUM HANDLING AND CONTRACTILITY IN CARDIOMYOCYTES. Micah Yoder , Maria Papa daki, Ahmed Zied, Evan Kelly, Brandon Markle, David D.L. Minh, Grace Muller, Jonathan A. Kirk 2529-Plat 1:30 pm SYNAPTIC FORCE SHIELDING IN T-CELL RECEPTOR-LIGAND INTERAC TIONS. Lukas Schrangl , Florian Kellner, Rene Platzer, José L. Toca-Herre ra, Johannes B. Huppa, Gerhard J. Schuetz, Janett Goehring 2530-Plat 1:45 pm CHARACTERIZING DIMERIZATION DYNAMICS OF FGFR3 AND TRKA TRANSMEMBRANE DOMAINS. Shashank Shastry , Zichen Wang 2531-Plat 2:00 pm GPCR REGULATION OF PLCB SIGNALING IN MACROPHAGES. Maria E. Falzone , Roderick MacKinnon, Priyam Banerjee 2532-Plat 2:15 pm MOLECULAR AND BIOPHYSICAL DETERMINANTS OF GROUP II MGLURS DESENSITIZATION AND INTERNALIZATION ACROSS A WIDE RANGE OF TIMESCALES. Alberto J. Gonzalez-Hernandez , Anisul Arefin, Sheida Sharghi Moshtaghin, Alexa Strauss, Nohely Abreu, Johannes Broichha gen, Marian Kalocsay, Joshua Levitz 2533-Plat 2:30 pm QUANTIFYING GPCR-G PROTEIN BINDING AFFINITY BY ANALYSIS OF STEADY-STATE FLUORESCENCE FLUCTUATIONS WITH TWO-COLOR IM AGE CUMULANT ANALYSIS. Teophile Lemay , Stephane Laporte, Paul W. Wiseman 2534-FlashTalk 2:45 pm Travel Award Winner SUPERRESOLUTION IMAGING OF THE NANOSCALE DISTRIBUTION OF CD81, CD63, AND CD9 ON JURKAT T CELL MICROVILLI INDICATES THEIR DISTINCT ROLES IN T CELL SIGNALING REGULATION. Neal T. Ramseier , Haoran Jing, Jesse Anderson, Ying S. Hu 2535-FlashTalk 2:50 pm WALTZ IN THE MEMBRANE: UNVEILING THE SPATIOTEMPORAL DYNAM ICS OF M1 MUSCARINIC RECEPTORS AND G PROTEINS. Xiaohan Zhou , Maria Shemeteva, Gurveen K. Dhillon, Richard J. Ward, Graeme Milligan, Claudiu C. Gradinaru 2536-FlashTalk 2:55 pm ALL ROADS LEAD TO ROME: CLASS B1 GPCRS SHOW DISTINCT ACTIVA TION MECHANISMS, BUT SIMILAR ACTIVE STATES. Prateek D. Bansal , Diwakar Shukla

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Co-Chairs Ingela Parmryd, University of Gothenburg, Sweden James Saenz, B CUBE, Center for Molecular Bioengineering, Germany 2517-Plat 1:00 pm HARNESSING MINIMAL CELLS TO UNDERSTAND THE DESIGN PRINCIPLES OF LIVING MEMBRANES. Nataliya Safronova, Isaac Justice, Petra Kiesel, Alexander von Appen, James P. Saenz 2518-Plat 1:15 pm INVESTIGATING THE EFFECT OF SPHINGOMYELIN COMPOSITION ON CHOLESTEROL FLIP-FLOP USING MACHINE-LEARNING-BASED EN HANCED SAMPLING METHODS. Parashara Shamaprasad , Edward R. Lyman 2519-Plat 1:30 pm EXPLORING THE ROLE OF PHOTOSWITCHABLE LIPIDS IN MEMBRANE SHAPE, PHASE BEHAVIOR AND PROTEIN GATING. Tsu-Wang Sun , Elias Sabri, Philip Stabler, Mina Aleksanyan, Naresh Yandrapalli, Antreas Vor kas, Ramona Schlesinger, Joachim Heberle, Rumiana Dimova 2520-Plat 1:45 pm MODELING HIGHLY COMPRESSED LIPID MONOLAYER IN-PLANE RELAX ATION WITH CONTINUUM ELASTICITY. Anna D. Gaffney , Dongxu Liu, Deepanjali Samal, Kathleen D. Cao, Angelo R. Carotenuto, Massimiliano Fraldi, Luca Deseri, Ka Yee C. Lee, Luka Pocivavsek, Nhung Nguyen 2521-Plat 2:00 pm EXTRACTING THE GAUSSIAN CURVATURE MODULUS BY SIMULATING LIPID MEMBRANES IN TRIPLY PERIODIC MINIMAL GEOMETRIES. Seamus Gallagher , Markus Deserno 2522-Plat 2:15 pm DOMAIN FORMATION DURING HOST MEMBRANE PERMEABILIZATION BY THE VIRULENCE-ASSOCIATED PROTEIN A FROM RHODOCOCCUS EQUI . Christian Nehls , Marcel Schröder, Thomas Haubenthal, Albert Haas, Thomas Gutsmann 2523-Plat 2:30 pm BIOPHYSICAL REGULATION OF AXON MORPHOLOGY AND PLASTICITY. Shigeki Watanabe , Jacqueline Griswold, Mayte Bonilla Quintana, Renee Pepper, Christopher T. Lee, Sumana Raychaudhuri , Sumana Raychaud huri , Padmini Rangamani 2524-FlashTalk 2:45 pm MODULATING INTERACTIONS BETWEEN SUPPORTED LIPID BILAYERS AND SOLID SURFACES TO STUDY MEMBRANE ACTIVE PEPTIDES BY NEUTRON REFLECTOMETRY. Megan E. Mitchell , Frank Heinrich, Ella Mihailescu, Erik Watkins, David P. Hoogerheide 2525-FlashTalk 2:50 pm Travel Award Winner USING HEMIFUSION TO FABRICATE AND CHARACTERIZE ASYMMETRIC MODEL MEMBRANES CONTAINING ANIONIC LIPIDS. Trevor A. Paratore , Jake McDonough, Hannah M. Ketelhohn, Alonzo H. Ross, Arne Gericke 2526-FlashTalk 2:55 pm INFERRING MEMBRANE FEATURES FROM MEMBRANE PROTEIN STRUC TURE. Bivek Pokhrel

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