BPS2025 Full Program

L3408-Pos Board LB27 MOLECULAR BASIS OF THE CYFIP2 AND NCKAP1 AUTISM-LINKED VARI ANTS IN THE WAVE REGULATORY COMPLEX. Paolo Ruggerone , Song Xie, Ke Zuo, Paolo Carloni, Silvia De Rubeis Membrane Protein Folding (Boards LB28 - LB28) L3409-Pos Board LB28 UNLOCKING NEW INSIGHTS INTO THE BETA-BARREL ASSEMBLY MACHINE: UTILIZING A NOVEL FLUORESCENT REPORTER TO QUANTIFY OUTER MEMBRANE PROTEIN FOLDING KINETICS. Whitney N. Bergman , Marcelo C. Sousa Enzyme Function, Cofactors, and Post-Translational Modifications (Boards LB29 - LB33) L3410-Pos Board LB29 STRUCTURE-ENABLED MACHINE LEARNING PREDICTION UNVEILS ELUSIVE TERPENOID BIOSYNTHESIS IN ARCHAEA. Raman Samusevich, Teo Hebra, Sotirios Kampranis, Josef Sivic, Tomas Pluskal L3411-Pos Board LB30 DISCOVERY OF NOVEL ALLOSTERIC ENZYME SITES USING HIGH-THROUGH PUT QUANTITATIVE MUTATIONAL SCANNING ASSAYS. Daniel Mokhtari , Ali Lashkaripour L3412-Pos Board LB31 QUANTIFYING RADIATION DAMAGE TO METALLOCOFACTORS IN CRYO EM. Christian Brininger , Chris Gisriel L3413-Pos Board LB32 LIGW AND W2: TWO DECARBOXYLASES, ONLY ONE METAL-DEPEN DENT. Paul Wolski , Andy DeGiovanni, Kenneth Sale, Blake A. Simmons, Jose H. Pereira, Paul D. Adams L3414-Pos Board LB33 HIGH-THROUGHPUT BIOCHEMICAL PHENOTYPING OF SHP2 VARIANTS: ILLUMINATING BIOCHEMICAL MECHANISMS AND ADVANCING PRECI SION MEDICINE. Albert A. Lee , Daniel Mokhtari, Dan Herschlag, Polly M. Fordyce Condensates in Physiology and Disease (Boards LB34 - LB36) L3415-Pos Board LB34 POLYGLUTAMINE EXPANSION ALTERS THE FUNCTIONAL SELF-ASSOCIATION OF THE ANDROGEN RECEPTOR. Levente Zodi , Carla Garcia-Cabau, Jesús García, Xavier Salvatella L3416-Pos Board LB35 INTERACTIONS BETWEEN THE PICORNAVIRUS 3CD PROTEASE AND RNA INDUCES LIQUID-LIQUID PHASE SEPARATION. Somnath Mondal , Kevin E. Namitz, Neela Yennawar, Saumyak Mukherjee, David D. Boehr L3417-Pos Board LB36 UPREGULATED MITOTIC PROTEIN MAD1 FORMS SHELL-LIKE NUCLEAR CONDENSATES IN HUMAN CANCER CELLS. Jasper Jeffrey , Sophia Staggers, Lian Wang, Mingqi Zhao, Stella Y. Sun, Huaiying Zhang DNA Replication, Recombination, and Repair (Boards LB37 - LB41) L3418-Pos Board LB37 RESOLVING NUCLEOTIDE OCCUPANCY STATES DRIVING MUTS-DNA CONFORMATIONAL CHANGES IN DNA MISMATCH REPAIR USING SINGLE MOLECULE FRET EXPERIMENTS AND MICROFLUIDICS. John M. Middleton , Dorothy A. Erie

L3419-Pos Board LB38 DECODING THE DYNAMIC STRUCTURE OF EXOI IN DNA MISMATCH REPAIR: A NOVEL PERSPECTIVE USING AFM. Corey L. Davis , Aryaman Bana, Hunter Wilkins, Dorothy A. Erie L3420-Pos Board LB39 ELUCIDATING EXO1’S KEY INTERACTIONS WITH MUTS IN DNA MISMATCH REPAIR VIA ATOMIC FORCE MICROSCOPY. Aryaman Bana , Corey L. Davis, Dorothy A. Erie L3421-Pos Board LB40 INVESTIGATING THE NON-HOMOLOGOUS END JOINING MACHINERY US ING DNA NANOMANIPULATION. Fianzo C. Smith-Clarke , Terence R. Strick, Fredrik Westerlund, Jean-baptiste Charbonnier, Jaouen Tran-Rajau L3422-Pos Board LB41 A DNA BINDING PROTEIN INTERACTS WITH TYPE II TOPOISOMERASES TO PROMOTE DNA REPLICATION. Tara M. Young , Katie Leung, Monica S. Guo Transcription (Boards LB42 - LB44) L3423-Pos Board LB42 SINGLE MOLECULE STUDY OF CO-TRANSCRIPTIONAL R-LOOP FORMATION DURING BACTERIAL TRANSCRIPTION INITIATION. Julien Le Gall , James R. Portman, Terence R. Strick L3424-Pos Board LB43 ASSAY TRANSCRIPTION WITH QUANTITATIVE PCR. Suleyman Ucuncuoglu , Narendar Kolimi, Bing Wang, Irina Artsimovitch, Laura Finzi, David Dunlap L3425-Pos Board LB44 TRANSCRIPTION FACTOR SPATIAL ORGANIZATION AND DYNAMICS AT NUCLEAR CONDENSATES. Mehdi Shafiei Aporvari , Alisha Budhathoki, Ganesh Pandey, Filmon Medhanie, Jan-Hendrik Spille Chromatin and the Nucleoid (Boards LB45 - LB46) L3426-Pos Board LB45 MECHANICAL INSIGHT INTO CENTROMERIC EVOLUTION. Jayeeta Kolay , Daniël P. Melters, Minh Bui, Yamini Dalal L3427-Pos Board LB46 ASSEMBLY OF H1 LINKER HISTONE WITH NUCLEOSOME: NANOSCALE CHARACTERIZATION. Ahmed Yesvi Rafa , Shaun Filliaux, Yuri L. Lyubchenko Membrane Fusion and Non-Bilayer Structures (Boards LB47 - LB47) L3428-Pos Board LB47 SYNTAXIN 1B DEFICIENCY REDUCES VESICLE PRIMING AND ENHANCES SYNAPTIC DEPRESSION AT THE CALYX OF HELD SYNAPSES. Jianli Guo, Xuefeng Wang, Hao Tian, Jianyuan Sun , Peihua Chen Protein-Lipid Interactions: Channels (Boards LB48 - LB48) L3429-Pos Board LB48 THE EFFECTS OF LIPID COMPOSITION ON ALPHA-SYNUCLEIN-MEMBRANE INTERACTION PROBED BY THE GRAMICIDIN A BIOSENSOR. William A. Milhizer , Kaitlin Abrantes, Sergey M. Bezrukov, Tatiana K. Rostovtseva General Protein-Lipid Interactions (Boards LB49 - LB51) L3430-Pos Board LB49 BILAYER-MODIFYING POTENCY PREDICTS CYTOXICITY IN A LIBRARY OF SMALL-MOLECULE SAC INHIBITORS. Rian Kacmarczyk, Henry Sliker, Tom Rossetti, Radda Rusinova, David J. Huggins, Lonny R. Levin, Jochen Buck, Olaf S. Andersen

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