BPS2026 Program Book

Career Development Center Workshop The Art and Science of Resubmissions of NIH Proposals 4:00 pm - 5:00 pm, Esplanade, Room 151

Platform Protein Stability, Folding, and Chaperones 4:00 pm - 6:00 pm, Room 201/202/203 Co-Chairs Amir Bitran, Harvard University, USA Christina Sizun, Centre National de la Recherche Scientifique ICSN, France 776-Plat 4:00 pm STRUCTURAL PLASTICITY OF RSV NS1 PROTEIN MAY AS A DRIVER OF MULTIFUNCTIONALITY. Jiawei Dong, Celia Ait-Mouhoub, Alexis Verger, Monika Bajorek, Christina Sizun 777-Plat 4:15 pm EXPLORING THE DYNAMICS OF SECA/SECB-DEPENDENT TRANSLOCA TION IN E. COLI USING SINGLE-MOLECULE TRACKING. Linnea Wikström , Tora Hävermark, Ivan L. Volkov, Erik Lundin, Mikhail Metelev, Gerrit Brandis, Magnus Johansson 778-Plat 4:30 pm Travel Award Winner PHOTON COUNTING HISTOGRAM ANALYSIS OF MOLECULAR OLIGO MERIZATION STATE IN LIVING CELLS. Zixiao Li , Tyler Camp, Teak-Jung Oh, Yushan Li, Kai Zhang 779-Plat 4:45 pm TOWARDS A DETAILED MOLECULAR PICTURE OF CO-TRANSLATIONAL FOLDING DURING REAL-TIME TRANSLATION. Amir Bitran , Carlos Busta mante, Susan Marqusee 780-Plat 5:00 pm SURVEYING THE SEQUENCE CONSTRAINTS OF FOLDING ON THE RIBO SOME BY DEEP MUTATIONAL SCANNING. Rohan Bhardwaj , Caden Sillman, Charles P. Kuntz, Brianna Corman, Joseph P. Robinson, Jonathan P. Schlebach 781-Plat 5:15 pm STRUCTURAL AND DYNAMIC INSIGHTS INTO NASCENT-PROTEIN IN TERACTIONS WITH THE TRIGGER FACTOR CHAPERONE. Neomi Millan , Hongoing Guan, Zhemin Zhang, Edward W. Yu, Silvia Cavagnero 782-Plat 5:30 pm NOVEL MECHANISTIC DIVERGENCE OF THE HSP70-HSP110 CHAPERONE SYSTEM IN FUNGI AND HUMANS. Justin M. Kidd , Ayil Perrott, Cancan Sun, Anusri Arun Prasath, Spoorti Kalashetti, Vadim Barnakov, Sky Evans, Qinglian Liu 783-FlashTalk 5:45 pm TRACKING PRION EVOLUTION AS IT HAPPENS. Ioanna Chatzitheodo siou , Kezia Jack, Mark Batchelor, Jan Bieschke 784-FlashTalk 5:50 pm Travel Award Winner APOLIPOPROTEIN E LIPIDATION STATE MODULATES AMYLOID BETA INTERACTION AND SUBSEQUENT UPTAKE BY HUMAN ASTROCYTES. Kamila Nurmakova , Zachary Levine 785-FlashTalk 5:55 pm MULTI-PATHWAY AMYLOID AGGREGATION CAPTURES FIBRIL POLYMOR PHISM AND MORPHOLOGICAL EVOLUTION. Kamal Bhandari , Wuzhou Xiong, Tianyi Hou, Feng Ding

M O N D A Y

A focused look at how to navigate the logic, timing, and reviewer expec tations of NIH resubmissions, while also developing the judgment and narrative finesse that can turn critique into a compelling second chance. Symposium Catalysis Inside the Membrane Core 4:00 pm - 6:00 pm, Room 301/302 Chair Anirban Banerjee, NICHD, NIH, USA 766-Symp 4:00 pm STRUCTURAL BASIS FOR MEMBRANE-PROXIMAL PROTEOLYSIS OF SUBSTRATES BY THE Α-SECRETASE ADAM10 AND ITS MODULATION BY TETRASPANIN PROTEINS. Stephen C. Blacklow 767-Symp 4:25 pm STRUCTURE AND FUNCTION OF COPPER MEMBRANE MONOOXYGEN ASES. Amy C. Rosenzweig 768-Symp 4:50 pm SOLUTION STRUCTURES OF AN INTRAMEMBRANE ASPARTYL PROTEASE AND ITS LIPID BILAYER ENVIRONMENT OBTAINED VIA SANS. Raquel Lieberman 769-SympSelect 5:15 pm A VARIANT OF THE MENB STRAIN OF SYNECHOCYSTIS SP. PCC 6803 DIS RUPTS A STRESS RESPONSE PATHWAY, INCORPORATING AN UNUSUAL QUINONE IN THE ELECTRON TRANSFER PATHWAY OF PHOTOSYSTEM I. K V. Lakshmi , Brandon Russell, Vasily Kurashov, David Iwig, Patrick Landry, Christopher Gisriel, Wade Johnson, Gary W. Brudvig, Art van der Est, John Golbeck, David Vinyard 770-Symp 5:35 pm GETTING FAT AT THE MEMBRANE - STRUCTURE AND MECHANISM OF PROTEIN FATTY ACYLATION BY ZDHHC PROTEIN S-ACYLTRANSFERASES. Anirban Banerjee Symposium Cell Mechanosensing and Mechanotransduction 4:00 pm - 6:00 pm, Room 303/304 Chair Brenton Hoffman, Duke University, USA 771-Symp 4:00 pm MATRIX MECHANOBIOLOGY REGULATES PRO-FIBROTIC CARDIAC FIBRO BLAST ACTIVATION. Adam J. Engler 772-Symp 4:25 pm 3D SPHEROID MODELS FOR CANCER CELL MECHANOBIOLOGY. Jennifer Shin , Youngbin Cho, Jiwon Kim, Hyuntae Jeong 773-Symp 4:50 pm STRESS ASSOCIATED WITH GENOME IMBALANCE. Rong Li 774-SympSelect 5:15 pm MECHANOSENSITIVE NUCLEAR TENSION DETERMINES PROGRESSION OF NUCLEAR WRINKLING AND CHROMATIN REMODELING IN HUTCHIN SON-GILFORD PROGERIA SYNDROME. Dong-Hwee Kim 775-Symp 5:35 pm PROBING THE EFFECTS OF MOLECULAR TENSION ON PROTEIN FUNC TION IN CELLULO. Brenton D. Hoffman

72