BPS2026 Program Book

904-Pos Board B78 STRUCTURAL BASIS FOR MEMBRANE MICRODOMAIN FORMATION BY A HUMAN STOMATIN COMPLEX. Jack Stoner , Shufang Li, Ziao Fu 905-Pos Board B79 SHEDDING LIGHT ON THE DARK CHANNEL VIA LARGE-SCALE ION CHAN NEL CLASSIFICATION. Sarah I. Keuning 906-Pos Board B80 AI MODELLING AND MOLECULAR DYNAMICS REVEAL A PRE-CLEAVAGE COMPLEX BETWEEN PINK1 AND PARL. Robin A. Corey , Ian Collinson 907-Pos Board B81 CRYO-EM STRUCTURE OF TRPM1 REVEALS A NON-CANONICAL ARCHI TECTURE WITH AN INVERTED TRANSMEMBRANE DOMAIN. Michael Fabrizio , Chen Zhao, Mackenzie Brewer, Nebojša Bogdanovic 908-Pos Board B82 CONFORMATIONAL ANALYSIS OF THE N-TERMINAL ECTODOMAIN OF MEMBRANE-BOUND INFLUENZA A M2 PROTEIN IN COMPLEX WITH AN ANTIBODY. Lauren Ghil , Winston Zhang, Kathleen P. Howard 909-Pos Board B83 Travel Award Winner G-PROTEIN-COUPLED RECEPTORS ARE CONTROLLED BY WATER. Zachary T. Bachler , Kushani S.K. Hewage, Evelyn W. Cheng, Hibba Ahmed, Steven D.E. Fried, Helen F. Mann, Audrey M. Zener, Rylan M. Hammond, Suchithranga M.D.C. Perera, Andrey V. Struts, Michael F. Brown 910-Pos Board B84 IN SILICO STUDY OF ION PERMEATION MECHANISMS OF THE MOUSE TMC-1-CIB2-TMIE COMPLEX. Dolores Columba Perez-Flores , Ryan L. Woltz, Igor V. Vorobyov, Nipavan Chiamvimonvat, Ebenezer N. Yamoah 911-Pos Board B85 ACTIVATION OF HUMAN Β-DEFENSIN-3 BOUND TO CHEMOKINE RECEP TOR CCR7 VIA Β-ARRESTIN-MEDIATED SIGNALING PATHWAY IS CRUCIAL IN ORAL SQUAMOUS CELL CARCINOMA PROGRESSION. Chun-Chun Chang 912-Pos Board B86 TRPV1 ANTAGONISM OCCURS THROUGH DIVERSE STRUCTURAL MECHANISMS. Kyle E. Lopez , Sonali Mudiyanselage, Wade D. Van Horn 913-Pos Board B87 ISOLATING LOW EXPRESSION LEVEL INTEGRAL MEMBRANE PROTEINS IN PLASMA MEMBRANE-DERIVED VESICLES FOR STRUCTURAL STUD IES. Gabriel Cuce , Chen Zhao 914-Pos Board B88 EXPLORING THE ORIENTATION AND ALIGNMENT OF THE VIRAL PROTEIN GP28 THAT DISRUPTS BACTERIAL MEMBRANES. Binaya K. Baral , Indra D. Sahu, Andrew K. Morris, Evelyn A. Okorafor, Gary A. Lorigan 915-Pos Board B89 SIMULATIONS OF THE OUTWARD-FACING STATE OF V SGLT REVEAL DE TAILS OF SUGAR AND NA + RECOGNITION DURING TRANSPORT. Yisheng Zheng , Thorsten Althoff, Kang Zhou, Jeff Abramson, Michael Grabe, Hong Zhou, Ernest M. Wright, Thomas Shockey 916-Pos Board B90 DISCOVERY AND CHARACTERIZATION OF AN INHIBITORY ANTI-CD19 NANOBODY. Luis Oliva 917-Pos Board B91 Travel Award Winner STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE HUMAN VITAMIN C TRANPORTER 2 (HSVCT2). Lok I Chan , Bernadette Byrne 918-Pos Board B92 Travel Award Winner TIME-RESOLVED XFEL STRUCTURES OF THE INTERMEDIATES OF THE

ULTRA-FAST LIGHT REACTION OF PHOTOSYSTEM I. Moritz Kretzschmar 919-Pos Board B93 STRUCTURAL DETERMINATION OF THE ELEVATOR-TYPE MOVEMENT OF ZIP PROTEINS. Nirsanka Roy , Lynn Goss Schrag, Petra Fromme 920-Pos Board B94 Travel Award Winner VASORIN MODULATES LIGAND-DEPENDENT ASSEMBLY OF TGFΒ RECEP TOR COMPLEXES IN LIVE CELLS. Prince Ozioma Emmanuel , Adam W. Smith 921-Pos Board B95 CRYO-ET IDENTIFIES CLAUDIN-15-DEPENDENT TIGHT JUNCTION PORES. Evgeniya Demchenko, Sarah McGuinness , Ye Li, Shaun Wood, Victoria Pappas, Jotham Austin, Le Shen, Fatemeh Khalili-Araghi, Chris topher Weber 922-Pos Board B96 LIPID AND DOMAIN INTERACTIONS DRIVE DISTINCT ACTIVATION PATH WAYS IN EPHA1 VS. EPHA2. Amita R. Sahoo , Matthias Buck 923-Pos Board B97 CCDC32 COLLABORATES WITH THE MEMBRANE TO ASSEMBLE THE AP-2 CLATHRIN ADAPTOR COMPLEX. Dillon Sloan , Ariel Matthews, Haruaki Yanagisawa, Tanita Tedamrongwanish, Kevin Cannon, Jake Simmons, Garrett Chappell, Nathan Nicely, Rebecca B. Berlow, Masahide Kikkawa, Richard Baker 924-Pos Board B98 Travel Award Winner DIMENSIONALITY REDUCTION AND CLUSTERING IDENTIFY GPCR MI CROSWITCHES. Jingjing Ji , Edward R. Lyman Intrinsically Disordered Proteins II (Boards B99 - B116) 925-Pos Board B99 ION SPECIFIC MODULATION OF MBD3 PHASE SEPARATION VIA ITS ACIDIC DISORDERED REGION. Ahmed H. Mousa , Alaji Bah 926-Pos Board B100 INVESTIGATING THE ROLE OF RNA IN DHH1 BIOMOLECULAR CONDEN SATES. Karl Pang , Wayne Yang, Aleksandra Radenovic 927-Pos Board B101 THEORETICAL POLYMER PHYSICS PREDICTION OF SEQUENCE-DEPEN DENT PARTITIONING OF INTRINSICALLY DISORDERED PROTEINS INTO BIOMOLECULAR CONDENSATES UNDERSCORES ROLE OF DYNAMIC, MULTIVALENT “FUZZY” MOLECULAR RECOGNITION IN SPECIFICITY. Jo nas Wessén, Nancy De La Cruz, Heankel Lyons, Hue Sun Chan , Benjamin Board B102 ROLE OF RESIDUAL STRUCTURE IN INTRINSICALLY DISORDERED PROTEINS ON LIQUID-LIQUID PHASE SEPARATION. Sylvia Adomako , Matthias Heyden 929-Pos Board B103 NANOMETER-SCALE RNA PROTEIN CLUSTERS (RPCS) AS DYNAMIC HUBS FOR INITIATION RELATED DEAD-BOX HELICASES. Him Shweta , Masaaki Sokabe, Amber Yanas, Nancy Villa, Michael C. Owens, Kathy Fange Liu, Christopher S. Fraser, Yale E. Goldman 930-Pos Board B104 MOLECULAR MECHANISM OF ERD14 LIQUID LIQUID PHASE SEPARA TION UNDER STRESS-MIMICKING CONDITIONS. Hugh M. O’Neill , Alan C. Hicks, Qiu Zhang, Wellington C. Leite 931-Pos Board B105 GELATION OF THE INTRINSICALLY DISORDERED TARDIGRADE PROTEIN CAHS-D PROTECTS AGAINST DESICCATION THROUGH A ROBUST PHASE TRANSITION. Haibei Zhang , Chris Anto, Kailin Guo, Aaron A. Huang, Paulina R. Martin, Disha Sanwal, Isabelle Shiiba, Victoria Torres, Adam T. Hammond R. Sabari 928-Pos

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