BPS2026 Program Book

Protein Structure Prediction (Boards B1 - B12) 1464-Pos Board B1 CONSTRUCTION OF DE NOVO Β-BARREL NANOPORES USING IN SILICO EVOLUTION. Mana Sato , Shoko Fujita, Tomoaki Matsuura, Ryuji Kawano 1465-Pos Board B2 A FEYNMAN PATH INTEGRAL APPROACH TO MODELING THE THERMO DYNAMIC PROPERTIES OF TOPOLOGICALLY-LINEAR POLYMERS. Timothy Leong 1466-Pos Board B3 Travel Award Winner DISSECTING THE HUMAN CYTOMEGALOVIRUS UL38:UL29 INTERACTION REGULATING HOST ANTIVIRAL RESPONSES. Eva M. Rodriguez , Megan Schumacher, Vanessa Leone, Scott Terhune, Dawn Wenzel 1467-Pos Board B4 INTERPRETABILITY IN PROTEIN DESIGN MACHINE LEARNING PRO GRAMS: DECODING PROTEINMPNN. Neel Mukkavilli , David A. Beck, Michelle E. McCully 1468-Pos Board B5 CONSERVED PATTERNS VS. RATIONAL DESIGN: FOLD-SWITCHING PATH WAYS IN A PHAGE TAIL PROTEIN. Devlina Chakravarty , Annie Sicong Li, Alan R. Davidson, Lauren L. Porter 1469-Pos Board B6 Travel Award Winner COMPUTATIONAL INVESTIGATION OF FACTOR V LEIDEN MUTATION: MOLECULAR DYNAMICS AND DOCKING ANALYSIS OF APC AND PS BIND ING. Audrey Brown , Bill Miller 1470-Pos Board B7 DEEP-LEARNING STRUCTURE ELUCIDATION FROM DOUBLE-MUTANT DEEP MUTATIONAL SCANNING. Zachary C. Drake , Steffen Lindert 1471-Pos Board B8 SIMULATION STUDY ON ORF8 STRUCTURE AND BINDING WITH IL-17RA RECEPTOR. Liqun Zhang , Hong Qin 1472-Pos Board B9 Travel Award Winner COMPUTATIONALLY MODELING STRUCTURAL CHANGES IN THE FACTOR V LEIDEN MUTATION TO PREVENT BLOOD CLOT DISORDERS. Isabelle M. Zagarri , Bill Miller 1473-Pos Board B10 DMCLOUD: LOCAL MODEL-MAP FITTING FOR LARGE MACROMO LECULAR STRUCTURE IN CRYO-EM MAPS. Genki Terashi , Xiao Wang, Yuanyuan Zhang, Han Zhu, Daisuke Kihara 1474-Pos Board B11 ALPHAFOLD CAN BE USED TO PREDICT THE OLIGOMERIC STATES OF PROTEINS. Yiechang Lin, Ciara Wallis , Ben Corry 1475-Pos Board B12 LARGE-SCALE PREDICTIONS OF ALTERNATIVE PROTEIN CONFORMA TIONS. Myeongsang Lee , Joseph W. Schafer, Jeshuwin D. Prabakaran, Devlina Chakravarty, Madeleine F. Clore, Lauren L. Porter Protein Stability, Folding, and Chaperones (Boards B13 - B45) 1476-Pos Board B13 Travel Award Winner A STRUCTURAL SNAPSHOT OF THE TA-DRIVEN RECONFIGURATION OF THE YEAST GET3-4/5 COMPLEX. Diego Granados-Villanueva , Marcelo Cevallos-Lira, Nu Thuy Anh Le, Kelly H. Kim 1477-Pos Board B14 THE MINIMAL FOLDING MOTIF OF THE REPEAT-IN-TOXIN DOMAIN OF ADENYLATE CYCLASE TOXIN. Guojun Chen , Han Wang, Suzana K. Straus, Hongbin Li

1478-Pos Travel Award Winner THERMAL STABILITY OF AI-DESIGNED PROTEIN CROWDERS. Caroline Davis , Becca Adams, Sadie Noble, Jordyn M. Markle, Gary J. Pielak 1479-Pos Board B16 DEAMIDATION SUBTLY CHANGES BIOPHYSICAL AND STRUCTURAL PROP ERTIES OF AN ANTARCTIC TOOTHFISH PROTEIN. Collin Sroge , Vanessa Encinas, Zane Long, Thomas Cao, Rayhan Fauzi Said Bawahab, Amanda Abiad, Rachel W. Martin 1480-Pos Board B17 BIOPHYSICS-INFORMED ASSESSMENT OF GENETIC MISSENSE VARIANTS IN HEARING LOSS. Rose A. Gogal , Genevieve Cox, Chloe Ovel, Richard J.H. Smith, Terry Braun, Michael J. Schnieders 1481-Pos Board B18 SELF-PROTEOLYTIC FRAGMENTATION PATTERNS OF SNAP-25. Robert H. Bates , Daniel C. Adams, Roxanne L. White, Fatima D. Dagohoy, Kyle G. Strong, Jurgen C. Mehlhaff, Kadan D. Brimhall, Dixon J. Woodbury 1482-Pos Board B19 STRUCTURAL INSIGHTS INTO HSP70-HSP110 COMPLEXES IN PROTEIN FOLDING. Ayil Perrott , Justin M. Kidd, Cancan Sun, Qinglian Liu 1483-Pos Board B20 NUCLEOPROTIN MUTATIONS LINKED TO PEDIATRIC RESPIRATORY VIRUS INFECTION. A COMPUTATIONAL STUDY. Mubasher Hassan, Saba Shahzadi, Andrzej Kloczkowski 1484-Pos Board B21 DECIPHERING THE MOLECULAR MECHANISM OF BACTERIAL CHAPER ONE SURA. Anne Herbert , Jonathan Machin, Joel A. Crossley, Katherine Fenn, Bob Schiffrin, Martin Walko, Luke Johnson, Anastasia Zhuravleva, Antonio Calabrese, Sheena E. Radford 1485-Pos Board B22 A NOVEL REAGENT FOR INVESTIGATING DISULFIDE-COUPLED FOLDING OF HIGH-MOLECULAR-WEIGHT PROTEIN. Nana Sakata , Shigeru Shima moto, Yuji Hidaka 1486-Pos Board B23 THE DELICATE ART OF CHAPERONING: A MOLECULAR VIEW OF THE CRITICAL WIP/WASP COMPLEX IN HEALTH AND DISEASE. Inna Sasson, Nina Vaizman, Adi Halle-Bikovski, Saja Baluom, Inbal Sher, Jordan H. Chill 1487-Pos Board B24 VISUALIZING CO-TRANSLATIONAL FOLDING PATHWAY MEDIATED BY MOLTEN-GLOBULE STATE. Yuichiro Konishi , Kanako Akamatsu, Takehito Tanzawa, Takayuki Kato 1488-Pos Board B25 BIOPHYSICAL AND FUNCTIONAL CHARACTERIZATION OF TWO BRCA1 BRCT MISSENSE MUTATIONS IDENTIFIED IN MENA REGION. Michail Nomikos , Salwa Al-Maraghi, Aya Alabdulrazzak, Tala Ismail, Safa Alz neika, Sara Fetais, Noof Al-Khal, Emna Riguene, Angelos Thanassoulas, Halema AlFarsi 1489-Pos Board B26 TWO-MOLECULE FORCE SPECTROSCOPY ON PROTEINS. Zehan Liu , Jiacheng Zuo, Hongbin Li 1490-Pos Board B27 IDENTIFYING PROTEIN UNFOLDING TRANSITION STATES VIA MO LECULAR DYNAMICS. Liam M. Pruitt , Jannik A. Gut, Thomas Lemmin, Michelle E. McCully Board B15

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