BPS2026 Program Book

Protein Structure Prediction (Boards LB1 - LB3) L2708 -Pos Board LB1 ALPHAFOLD MODELING OF POLYUBIQUITIN COMPLEXES. Balázs Fábián , Jan F.M. Stuke, Marcel Heinz, Gerhard Hummer L2709-Pos Board LB2 GENERALIZATION AND USABILITY OF CO-FOLDED GPCR-LIGAND COM PLEXES: A PHYSICS-GUIDED ASSESSMENT. Lichirui Zhang , Richard A. Friesner, Edward B. Miller, João Pedro Garcia Lopes Maia Rodrigues L2710-Pos Board LB3 DEVELOPMENT OF A PREDICTIVE MODELING WORKFLOW TO ASSESS STRUCTURAL AND OLIGOMERIC BEHAVIOR OF THERAPEUTIC PEPTIDES IN PHARMACEUTICAL FORMULATIONS. Rikhia Ghosh , Jiangbo Wu Protein Stability, Folding, and Chaperones (Boards LB4 - LB9) L2711-Pos Board LB4 USE OF IN SILICO PROTEIN STRUCTURE PREDICTION SOFTWARE WITH STRUCTURAL AND FUNCTIONAL STUDIES TO CHARACTERISE ERV14/ CORNICHON AND TRANSPORTER PROTEIN-PROTEIN INTERACTIONS. Board LB5 T-DEPENDENT STRUCTURE & DYNAMICS IN EXTREMOPHILE RUBREDOX INS UNDER EXTREME CONDITIONS. Stephen P. Cramer , Tzanko Doukov, Igor Leontyev, Francis Jenney L2713-Pos Board LB6 A PLATFORM FOR HIGH-THROUGHPUT MEASUREMENT OF PROTEIN STABILITY AND LIGAND BINDING. Shawn M. Costello , Daria Passow, Fanny Sunden, Polly M. Fordyce L2714-Pos Board LB7 HOW DO RIBOSOMES GUIDE DE NOVO PROTEIN FOLDING: FROM ENTROPIC DESTABILISATION OF THE UNFOLDED STATE TO FOLDING INITIATION. Ivana V. Bukvin , Julian O. Streit, Tomasz Wlodarski, Charity Hornby, Anais M.E. Cassaignau, John Christodoulou L2715-Pos Board LB8 STRUCTURAL DETERMINATION OF THE MITOCHONDRIAL AAA+ DIS AGGREGASE AND CHAPERONE, SKD3, WITH NATIVE SUBSTRATE TO UNRAVEL ITS MECHANISM. Amy M. Flis , Raju Roy, James Shorter, Daniel R. Southworth L2716-Pos Board LB9 ACCELERATING STRUCTURAL BIOLOGY WORKFLOWS THROUGH INTE GRATED BIOPHYSICAL CHARACTERIZATION. Nathan Wallace Intrinsically Disordered Proteins (Boards LB10 - LB25) L2717-Pos Board LB10 FOLDING DYNAMICS OF THE HUNTINGTIN EXON-1 PROTEIN. Morten Mosbach , Simon Ebbinghaus L2718-Pos Board LB11 COMBINING AI AND EXPERIMENTAL DATA TO REFINE ENSEMBLES OF INTRINSICALLY DISORDERED PROTEINS. Vincent Schnapka , Samiran Sen, Massimiliano Bonomi Jude Tunyi L2712-Pos

L2719-Pos Board LB12 DEVELOPMENT OF SYSTEMATICALLY COARSE-GRAINED FORCE FIELDS FOR INTRINSICALLY DISORDERED PROTEINS. Robert B. Best L2720 -Pos Board LB13 HYDROGEN-DEUTERIUM EXCHANGE OF DISORDER-CONTAINING COM PLEXES PROBES BOUND STATE ENSEMBLES. Joshua D. Morse , Darren N. Kahan, Susan Marqusee L2721-Pos Board LB14 ALPHAFLEX: ENSEMBLES OF THE HUMAN PROTEOME REPRESENTING DISORDERED REGIONS. Zi Hao Liu , Oufan Zhang, Stefano De Castro, Kunyang Sun, Hamidreza Ghafouri, Omar Abdelghani Attafi, Nicolas L. Fawzi, Silvio C.E. Tosatto, Alan M. Moses, Teresa L. Head-Gordon, Julie D. Forman-Kay L2722 -Pos Board LB15 RESIDUE-SPECIFIC MUTAGENESIS OF ABPSH3 REVEALS THE ROLE OF ELECTROSTATIC INTERACTIONS IN THE ARKA-SH3 BINDING PRO CESS. Jaden Ali , Oluebube Onwuzulu, K. Aurelia Ball, Elliott J. Stollar L2723-Pos Board LB16 BIOENGINEERING AND CHARACTERIZATION OF SPILT DISCS. Harnoor Nagra , Derek Applewhite, Shivani Ahuja L2724-Pos Board LB17 STRUCTURAL DYNAMICS WITHIN PQBP1 DETERMINE HIV-1 INNATE SENSING. Dale Allen , Sunnie Yoh, Ashok Deniz, Owen Pornillos, Sumit Chanda L2725-Pos Board LB18 DEVELOPMENT OF REFLECTIN CONSTRUCTS WITH IMPROVED SOLUBIL ITY AND OPTIMIZATION OF REFLECTIN PURIFICATION. Carlos Roberto Hoffmann Junior , Igor Chiriatev, Robert Levenson L2726 -Pos Board LB19 CKAP2 IS A MICROTUBULE POLYMERASE WITH AN INTRINSICALLY DISORDERED ENZYME DOMAIN. Tatiana Lyalina, Lia Paim, Luiz Da Silva, Susanne Bechstedt L2727 -Pos Board LB20 STRUCTURAL AND MECHANISTIC INSIGHTS INTO THE INTERPLAY BE TWEEN TRANSLATION DYNAMICS AND MISFOLDING IN HUNTINGTON’S DISEASE. Juliana Abramovich L2728 -Pos Board LB21 INVESTIGATION OF PHASE SEPARATION BEHAVIOR OF ELASTIN-LIKE POLYMERS USING HIGH-THROUGHPUT SCREENING AND STATISTICAL METHODS. Sam Spiese , Eva Rose M. Balog L2729-Pos Board LB22 LOCAL SR STRUCTURE AND VARIANT MUTATIONS FINE-TUNE LRH MEDIATED OLIGOMERIZATION OF SARS-COV-2 NUCLEOCAPSID PRO TEIN. Hannah Y. Stuwe , Elisar J. Barbar L2730-Pos Board LB23 SEQUENCE DETERMINANTS OF TUNABLE REFLECTIN ASSEMBLY. Muhammad Hannan Aslam , Anup Parajuli, Robert Levenson L2731-Pos Board LB24 REFLECTIN A1 ASSEMBLY INVESTIGATED VIA PHOSPHOMIMETIC AND TRUNCATED CONSTRUCTS. Igor Chiriatev , Carlos Roberto Hoffmann Junior, Robert Levenson L2732-Pos Board LB25 ELUCIDATING SEQUENCE-ENCODED CONFORMATIONAL ENSEMBLES AND BINDING SPECIFICITY OF DISORDERED BH3-ONLY PROTEINS. Angelica Lam , Margaux M. Pinney

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