BPS2026 Program Book

Condensates in Physiology and Disease (Boards LB26 - LB33)

L2744-Pos Board LB37 ITERATIVE EQUILIBRATION OF QUASI -SPHERICAL LIPID VESICLES VIA SHORT NONEQUILIBRIUM MD. Matteo Castelli , Lorenzo Casalino, Rom mie E. Amaro L2745-Pos Board LB38 COLLECTIVE VARIABLE-BASED SAMPLING IN MOLECULAR-DYNAMICS SIMULATIONS OF BIOMEMBRANES. Giacomo Fiorin , Haochuan Chen, Jérôme Hénin, Yein Christina Park, José D. Faraldo-Gómez, Lucy R. For rest L2746-Pos Board LB39 COMPARATIVE SKIN PERMEATION OF COSMETIC AND MEDICAL-GRADE VITAMIN A DERIVATIVES UTILIZING AN ARTIFICIAL SKIN MODEL. Lara Cadete L2747-Pos Board LB40 INTERACTION OF ACETAMINOPHEN WITH MODEL LIPID MEM BRANES. Rahber B. Syeda , Gabrielle Tomich, Mallory Saldana, Emmanu el O. Osei, Horia I. Petrache L2748-Pos Board LB41 TUNING VESICLE MECHANICS: CHOLESTEROL-DRIVEN CHANGES IN LIPOSOME SIZE AND DIFFUSION. Fawaz Baig , Lanqin Cao, Hassan Bazzi, Nazik Ebrahem, Krisanu Bandyopadhyay, Suvranta Tripathy Protein-Lipid Interactions: Structure (Boards LB42 - LB49) L2749-Pos Board LB42 INTERACTION OF AΒ40 WITH LIPID MEMBRANES: MOLECULAR MECHA NISMS FOR THE CHOLESTEROL CATALYSIS OF AGGREGATION. Rishiram Baral , Ruan van Deventer, Yuri L. Lyubchenko L2750-Pos Board LB43 COMPETITION BETWEEN A TRANSMEMBRANE HELIX ON SCAP AND A MEMBRANE CHOLESTEROL REGULATES SCAP-INSIG INTERACTION AND SREBP ACTIVATION. Blake C. Williams , Daniel L. Kober, Xiao-chen Bai, Arun Radhakrishnan, Daniel M. Rosenbaum L2751-Pos Board LB44 JMD-TMD-LIPID INTERACTIONS COOPERATIVELY MAINTAIN SYNTAXIN FUSOGENIC CONFIGURATION. Dong An , Manfred Lindau L2752-Pos Board LB45 THE INTERPLAY OF TAU AND AMYLOID PROTEINS IN THE MEMBRANE ASSOCIATED AGGREGATION. Rakhi Chowdhury , Yuri L. Lyubchenko L2753-Pos Board LB46 LIPID DRIVEN BASAL ACTIVITY OF THE BETA-2 ADRENERGIC RECEP TOR. Felix Eurasto , Shreyas Kaptan, Santeri Paajanen, Waldemar Kulig, Ilpo Vattulainen L2754-Pos Board LB47 STRUCTURAL BASIS OF LIPID RECOGNITION BY ZINC-Α2-GLYCOPROTEIN THROUGH A PRE-FORMED Α1-Α2 BINDING GROOVE. Wenhao Hu , Ste phen J. Perkins, Alun R. Coker, Lindsay C. McDermott L2755-Pos Board LB48 MITOCHONDRIAL MEMBRANE-ASSOCIATED LIQUID-LIQUID PHASE SEPARATION OF Α-SYNUCLEIN ATTENUATES CYTOTOXICITY. Jianing Zhang , Vince S.D. Mesias, Shijie Chen, Xin Dai, Jinqing Huang L2756-Pos Board LB49 COUPLING BETWEEN CONFORMATIONAL STATE, OLIGOMERIC AS SEMBLY, AND LIPID ENVIRONMENT IN HIV FUSION PEPTIDES. Shreyaa Srinivasan , Peter Kasson

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L2733-Pos Board LB26 DECODING INTRINSICALLY DISORDERED REGION MUTATIONS IN P53 UTILIZING DEEP MUTAGENESIS BY HIGH-THROUGHPUT IMAGE-BASED SCREENING. Arianna Silva-Torres L2734-Pos Board LB27 HIERARCHICAL INTERACTIONS BETWEEN NUCLEOLAR AND HETERO CHROMATIN CONDENSATES ARE MEDIATED BY A DUAL-AFFINITY PROTEIN. Varsha Rajshekar , Omar Adame-Arana, Gaurav Bajpai, Serafin Colmenares, Hannah Papoi, Lucy D. Brennan, Shingo Tsukamoto, Samuel Safran, Gary Karpen L2735-Pos Board LB28 A METHIONINE SWITCH AND A LINEAR MOTIF WITHIN AN INTRINSICAL LY DISORDERED SEGMENT MEDIATE REDOX-DEPENDENT CONDENSA TION BY THE STRESS RESPONSE FACTOR HSSB1. János Pálinkás , Krisztina Csipkay, Juan Laglaguano, Usman Ashraf Awan, Viktoria Katran, Peter Ecsédi, Bálint Jezsó, Benedek Kiss, Gabriella Gellén, Zoltan J. Kovacs, Tibor Kovács, Gitta Schlosser, Mihaly Kovacs L2736-Pos Board LB29 FUNCTIONAL ORGANIZATION OF CYTOPLASMIC HYPEROSMOTIC PHASE SEPARATION (HOPS) CONDENSATES. Bisal Halder L2737-Pos Board LB30 REGULATING MECHANOTRANSDUCTION BY TUNING CONDENSATE MATERIAL PROPERTIES. Xiaohang Cheng , Sophy Voung, Huan Wang, Zheng Shi, Lindsay Case L2738-Pos Board LB31 HISTONE TAIL SPECIFICITY IN REGULATING CHROMATIN PHASE BEHAV IOR. Manisha Poudyal , Ramya Billur, Bryan Gibson L2739-Pos Board LB32 ANDROGEN RECEPTOR VARIANT 7 CONDENSATES DRIVE GROWTH AND PROLIFERATION IN CASTRATION-RESISTANT PROSTATE CANCER. Shab nam Massah, Nicholas C. Pinette, Mailyn Terrado, Sumanjit Datta, Robert Bell, Tahsin Emirhan Tekoglu, Nathan A. Lack, Martin E. Gleave, Suhn Rhie, Colin Collins, Joerg Gsponer, Nada Lallous L2740-Pos Board LB33 CONDENSATE METASTABILITY GOVERNS THE RATE OF FIBRIL FORMA TION IN A PHASE SEPARATED SYSTEM: IMPLICATIONS FOR THE ROLE OF STRESS GRANULES IN ALS. Fatima K Zaidi Membrane Structure (Boards LB34 - LB41) L2741-Pos Board LB34 HIGH-THROUGHPUT ANALYSIS OF THE CONTENT AND PROPERTIES OF NANO-SIZED BIOPARTICLES WITH SINGLE-PARTICLE PROFILER. Taras Sych , Selim Tanriverdi, Jan Schlegel, Andre Goergens, Miina Ojansiivu, Dunya Aydos, Ceylan Verda Bitirim, Hanna Barriga, Samir EL Andaloussi, Aman Russom, Erdinc Sezgin L2742-Pos Board LB35 LIPID COMPOSITION INFLUENCES THE FORMATION OF VESICLE LAMEL LARITY. Obed Obeng-Gyasi L2743-Pos Board LB36 COLISTIN-INDUCED STRUCTURAL AND FUNCTIONAL ALTERATIONS IN MODEL BACTERIAL MEMBRANES. Modestas Mažerimas

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