BPS2026 Program Book

Calcium Signaling (Boards LB50 - LB53)

L2767 -Pos Board LB60 TCA CYCLE METABOLONS IN CARDIAC MITOCHONDRIA. Xinyi Qian, Gisela Beutner, Paul S. Brookes, George A. Porter L2768 -Pos Board LB61 NEUROPROTECTIVE EFFECTS OF IDEBENONE IN FERROPTOSIS MODEL ON HUMAN ASTROCYTES. Luke Chandler , Morgan Stetzer, Andrea C. Jimenez-Vergara, Genevieve Dakour, Elizabeth Newland, German Plascencia-Villa, George Perry, Dany J. Munoz-Pinto L2769-Pos Board LB62 MALE RAT ISOLATED CARDIAC MITOCHONDRIA ARE MORE SENSITIVE TO CALCIUM OVERLOAD. Alyssa C. Vadovsky , Jason N. Bazil L2770 -Pos Board LB63 CALMODULIN ENHANCEMENT OF MCU FUNCTION IN ISOLATED MITO CHONDRIA OBTAINED FROM HEART OR LIVER: DOES MICU STOICHI OMETRY MATTER? Sara Garcia , Vasco Sequeira Olivera, Christopher N. Johnson L2771-Pos Board LB64 CRYO-ET REVEALS CA 2+ -INDUCED CHANGES IN ATP SYNTHASE IN NATIVE MEMBRANES. Louis Perez, Oleg Klykov, Maria A. Neginskaya L2772 -Pos Board LB65 ABLATION OF CHLORIDE INTRACELLULAR CHANNEL 1, CLIC1, AUG MENTS DIABETES-ASSOCIATED CARDIOMYOPATHY BY AFFECTING GLUT4 EXPRESSION AND MITOCHONDRIAL FUNCTION. Shrey Stallard , Ty Williams, Maren Klineberg, John Edwards, Harpreet Singh, Devasena Board LB66 LIPID-SENSING FIS1 IS A DRP1-INDEPENDENT MEMBRANE REMODEL ING MACHINE. Anshuman Mohapatra, Anelise Hutson, Shenaz Khan, Jeffrey Schelling, Jason A. Mears, Rajesh Ramachandran L2774-Pos Board LB67 VOLUME EM ANALYSIS OF CARDIAC MITOCHONDRIAL CRISTAE AT CON TACTS WITH THE JUNCTIONAL SR. Ariele Baggett, Aron Andresi, Zuzana Nichtova, David B. Weaver, Shey-Shing Sheu, Gyorgy Csordas Voltage-Gated Na Channels (Boards LB68 - LB71) L2775-Pos Board LB68 GPR35 MODULATES NAV1.9 TO SHAPE SENSORY NEURON EXCITABIL ITY. Frank Bosmans L2776 -Pos Board LB69 STRUCTURAL BASIS OF MULTILAYERED GATING AND FAST INACTIVATION MECHANISMS IN HUMAN NA V 1.5. Rupam Biswas L2777 -Pos Board LB70 ROLE OF VOLTAGE-SENSING DOMAIN IV IN Β1 MODULATION OF NAV1.6 GATING. Maxime Lammens , Alain J. Labro, Filip Van Petegem, Frank Bosmans L2778 -Pos Board LB71 A COMMON ROLE FOR THE Β1 SUBUNIT IN DISTINCT MECHANISMS OF NA V 1.5 REGULATION. Albert Rigat-Pujolàs, Rebecca Martinez-Moreno, David Carreras, Elisabet Roura, Natalia Garcia Quintanilla, Ramon Bruga da, Guillermo J. Perez, Fabiana S. Scornik Ponnalagu L2773-Pos

L2757-Pos Board LB50 TEMPERATURE OSCILLATIONS GENERATED BY CALCIUM-ATPASES (SERCA) AMPLIFY “COUPLED-CLOCK” PACEMAKER MECHANISMS IN SA NODE CELLS. Evgeny Kobrinsky , Akihiro Okamura, Victor A. Maltsev, Edward G. Lakatta L2758-Pos Board LB51 CALCIUM-DEPENDENT ARRHYTHMOGENESIS DRIVES EARLY ELECTRICAL INSTABILITY AFTER TRANSPLANT OF STEM CELL-DERIVED CARDIOMYO CYTES. Andrew P. Wescott , Elaheh Karbassi, Silvia Marchianò, Likitha Nimmagadda, Nora Perrault, Leslie Blakely, W. Robb MacLellan, Jennifer Davis, Charles Murry L2759-Pos Board LB52 INTERROGATING THE CHEMISTRY THAT GOVERNS CA 2+ MEDIATED CALMODULIN CONFORMATIONAL CHANGE AND ALLOSTERIC COMMU NICATION. Elice R. Mbuta, Sara A. Garcia, Justin R. Lovett, Christopher Board LB53 TYROSINE PHOSPHORYLATION OF MITOFUSIN 2 PROMOTES VENTRICU LAR FIBROSIS IN PULMONARY ARTERIAL HYPERTENSION. Jin O-Uchi , Bong Sook Jhun Bioenergetics and Photosynthesis (Boards LB54 - LB57) L2761-Pos Board LB54 A MACHINE LEARNING CHANGE POINT DETECTION METHOD FOR TESTING NUCLEOTIDE EXCHANGE IN F-ATPASE AND OTHER ROTARY BIOMOTORS. Sandor Volkan-Kacso , Robert Fenn, Noah Mejia, Alexan dra Szolnoki L2762 -Pos Board LB55 EXPLORING BINDING POSES OF PHOTOSYSTEM I AND FERREDOXIN ISOFORMS IN CHLAMYDOMONAS REINHARDTII USING ALPHAFOLD3 AND MOLECULAR SIMULATIONS. Clark Hofstrand , Jonathan T. Nguyen, Daipayan Sarkar, Stefan Schmollinger, Daniela Strenkert, Josh V. Vermaas L2763-Pos Board LB56 A MATHEMATICAL MODEL OF CELL VOLUME CONTROL WITH REALISTIC NA⁺/K⁺ PUMP DYNAMICS. Evan Rowbotham , Charles Peskin L2764-Pos Board LB57 IDENTIFYING CRITICAL PIGMENTS AND PATHWAYS IN PHOTOSYNTHETIC ENERGY-TRANSFER NETWORKS. Zane E. Armijo , William P. Bricker Mitochondria in Cell Life and Death (Boards LB58 - LB67) L2765-Pos Board LB58 RESVERATROL ACTIVATES THE ATP SYNTHASE C-SUBUNIT LEAK CHAN NEL BY TRIGGERING LARGE-SCALE CONFORMATIONAL CHANGES WITHIN ITS STRUCTURE. Amrendra Kumar , Juliana da Fonseca Rezende e Mello, Yangyu Wu, Nelli Mnatsakanyan L2766 -Pos Board LB59 MITOCHONDRIAL FUSION AND NETWORK ADAPTATIONS TO META BOLIC STRESS ARE UNDER OPPOSING EFFECTS OF THE MITOCHONDRIAL CALCIUM UNIPORTER GATEKEEPERS, MICU1 AND MICU2. Benjamin Cartes Saavedra , Elena V. Berezhnaya, Macarena Rodriguez Prados, Prottoy Hasan, Peter Varnai, Fabiana Perocchi, Gyorgy Hajnoczky N. Johnson L2760 -Pos

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