BPS2026 Program Book

Protein-Nucleic Acid Interaction II (Boards B94 - B123)

2123-Pos Travel Award Winner APOLIPOPROTEIN E LIPIDATION STATE MODULATES AMYLOID BETA INTERACTION AND SUBSEQUENT UPTAKE BY HUMAN ASTROCYTES. Kamila Nurmakova , Zachary Levine Genome Maintenance (Boards B82 - B93) 2124-Pos Board B82 INVESTIGATION OF THE INTERACTIONS SUPPORTING RIBOSOMAL ANTI TERMINATION IN BACILLUS SUBTILIS. Thao N.P. Tran 2125-Pos Board B83 MATRIX STIFFNESS DRIVES CELLULAR SENESCENCE THROUGH DISRUP TION OF NUCLEAR ARCHITECTURE AND CHROMATIN REMODELING. Rohit Joshi , Vinayak Vinayak, Vivek B. Shenoy 2126-Pos Board B84 SLIMVAR MICROSCOPY FOR RAPID IN VIVO SINGLE-MOLECULE TRACK ING OF CHROMATIN REGULATORS IN PLANTS. Alex L. Payne-Dwyer 2127-Pos Board B85 QUANTITATIVE SUPER-RESOLUTION MICROSCOPY OF DNA DAMAGE AND REPAIR FOR MECHANISTIC INSIGHT INTO THE FLASH EFFECT IN RADIATION THERAPY. Henry Gatica-Gutierrez , Brett Velasquez, Gabriella Gagliano, Alex Raterink, Prakash Joshi, Emil Schueler, Anna-Karin Gus tavsson 2128-Pos Board B86 TRANSCRIPTION DYNAMICS OF SARS-COV-2 POLYMERASE IN RNA SYNTHESIS AND SUB GENOMIC TEMPLATE SWITCHING. Xiaohui Ma , Xinzhou Xu, Long Wai Tsui, Lin Yang, Shuqin Zheng, Mesias Vince St. Dol lente, Tongle Xu, Buyu Zhang, Lingxiang Jiang, Toyotaka Ishibashi, Peter Cheung, Jinqing Huang 2129-Pos Board B87 OPPOSING ROLES OF TWO R-LOOP ASSOCIATED G-QUADRUPLEXES IN TUNING TRANSCRIPTION ACTIVITY. Chun-Ying (Jim) Lee , Leya Yang, Tapas Paul, Sua Myong 2130-Pos Board B88 TFIIS ENHANCEMENT OF POL II CLEAVAGE IS KINETICALLY CON TROLLED. Ryan M. Requijo , David A. Schneider, Aaron L. Lucius 2131-Pos Board B89 A SWI4 COPY-NUMBER THRESHOLD MODEL PREDICTS CELL SIZE IN BUDDING YEAST. Abhishek Ghimire , Carleton Coffin, Roger Palou, Mike Tyers, Sylvain Tollis, Catherine A. Royer 2132-Pos Board B90 RECRUITMENT AND ASSEMBLY OF EARLY DNA DAMAGE CHECKPOINT FACTORS. Emily C. Beckwitt , Gabriella N. Chua, Shixin Liu, Michael Board B91 STRAIN IMPACTS THE DIFFUSIVITY AND LOCALIZATION OF LARGE SOL UTES IN POROELASTIC MEDIA. Alexander Marshall , Richard Superfine 2134-Pos Board B92 EPIGENETIC MODIFICATIONS OF CORE HISTONES DURING NDM-29 INDUCED RETRO-TRANSFORMATION OF NEUROBLASTOMA CELLS. Hawraa Zbeeb , Chourouk Joumaa, Aldo Pagano, Laura Vergani, Alberto Diaspro 2135-Pos Board B93 Travel Award Winner INVESTIGATING WERNER HELICASE KINETICS USING NANOPORE TWEE ZERS. Yahia Saad , Jonathan M. Craig, Lauren E. Vostal, Sarah J. Abell, Michaela C. Franzi, Eric Lebo, Zacharias M. Seitz, Jens H. Gundlach, Tarun M. Kapoor, Andrew H. Laszlo Board B81 O’Donnell 2133-Pos

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2136-Pos Board B94 NUCLEOTIDE AND GROOVE-SPECIFIC RECOGNITION OF DNA BY PROT AMINE. Anshika Dhiman , Hashini Ekanayake Mudiyanselage, Huan Xiang Zhou 2137-Pos Board B95 EXPLORING PROTEIN-RNA INTERACTIONS WITH CORRELATIVE SINGLE MOLECULE APPROACHES. Sheema Rahmanseresht , Paul Pease, Nasta ran Hadizadeh Yazdi, Trey Simpson 2138-Pos Board B96 INTRICATE REGULATION OF RNA CLEAVAGE AND SPLICING BY THE EN DORIBONUCLEASE IRE1. Swapnil Mukherjee, Jacob W. Smith, Vladislav Belyy 2139-Pos Board B97 NANOSCALE MAPPING OF SNORNA AND PROTEIN FLUXES IN THE LIVING NUCLEOLUS. Kai Sheng , Sijin Chen, Scott Henderson, James R. Williamson 2140-Pos Board B98 REDISTRIBUTION OF STRUCTURAL ENSEMBLES SHAPES FREE AND BOUND STATES OF HIV TAR RNA. Aiyana Monae , Rohit Roy, Supriya Pratihar, Hashim Al-Hashimi 2141-Pos Board B99 SINGLE-MOLECULE ANALYSIS TO VISUALIZE THE DIRECT INTERACTIONS OF PROTEINS AND DNA. Nastaran Hadizadeh Yazdi , Sheema Rahman seresht, Paul Pease, Trey Simpson 2142-Pos Board B100 SINGLE-STRANDED RNA BINDING TO SARS COV-2 NUCLEOCAPSID PRO TEIN: A FLUORESCENCE INVESTIGATION. Kathleen B. Hall , Katie Link, Madison Stringer, Jay R. Knutson, Andrea Soranno 2143-Pos Board B101 DEVELOPING AN ASSAY TO QUANTITATIVELY MEASURE PROTEIN-RNA INTERACTIONS IN THE CELLULAR CONTEXT. Shi Yu William Guo , Megan Ken 2144-Pos Board B102 HIGHLY SENSITIVE MAPPING OF E. COLI GYRASE AND TOPOISOMERASE IV CLEAVAGE OF GENOMIC DNA IN VITRO . Ian L. Morgan , Keir C. Neu man 2145-Pos Board B103 INVESTIGATION OF THE MUTSA INTERACTION WITH RECOMBINA TION INTERMEDIATES: AN ALTERNATE BINDING MECHANISM? Andrea Jimenez Benitez , Zane Lombardo, Tai Lon Tan, Tonya N. Zeczycki, Ishita Mukerji 2146-Pos Board B104 SYNERGISTIC ROLE OF RGG2 IN MODULATING FUS RRM STRUCTURE AND RNA BINDING REVEALED BY ENHANCED SAMPLING SIMULA TIONS. Kosar Rahimi , Ayush Gupta, Karim Malekzadeh, Gül H. Zerze 2147-Pos Board B105 KINETIC REGULATION OF A DEVELOPMENTAL DECISION BY PROTEIN DNA INTERCALATION. Joseph Racca, Yen-Shan Chen, Manohar Rad hakrishnan, Chun-Lun Ni, Ratan Kumar, Millie Georgiadis, Michael A. Weiss 2148-Pos Board B106 THERMODYNAMICS OF SARS-COV-2 NUCLEOCAPSID PROTEIN/ SSRNA(SSDNA) INTERACTIONS. Alexander G. Kozlov , Sumit K. Chaturve di, Timothy M. Lohman

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