BPS2026 Program Book

54-Plat 9:45 am MINIMIZING FIB-MILLING DAMAGE TO MAXIMIZE SIGNAL IN BIOLOGI CAL CRYO-LAMELLA. Laina N. Hall , Joshua Paul, Bronwyn Lucas 55-FlashTalk 10:00 am CRYO-ET FOR DIRECT MEASUREMENT OF PROTEIN INTERACTION PO TENTIALS. Ekaterina Poliukhina , Quy Khac Ong, Francesco Stellacci 56-FlashTalk 10:05 am NANOSCALE ARCHITECTURE OF FIELD-DERIVED FUNGAL-BACTERIAL SYMBIOSIS REVEALED BY CRYOGENIC ELECTRON TOMOGRAPHY. T. Bertie Ansell , Louis Berrios, Kabir Peay, Peter D. Dahlberg 57-FlashTalk 10:10 am LASER PHASE PLATE FOR ELECTRON MICROSCOPY. Eric S. Cooper , Petar Petrov, Jessie Zhang, Ian Hicklin, Hang Cheng, Shahar Sandhaus, Jeremy Axelrod, Jonathan Remis, Robert M. Glaeser, Holger Müller Platform Calcium Channels, Signaling, and Contraction 8:15 am - 10:15 am, Room 209/210/211 Co-Chairs Travel Award Winner DECIPHERING CALCIUM DYNAMICS IN INTESTINAL ORGANOIDS USING FLIM-FRET MICROSCOPY AND FUNCTIONAL CLUSTERING. Michele Cervellera , Hang Zhou, Guangchen Wang, Michael G. Monaghan, Ruslan Dmitriev 59-Plat 8:30 am INFERENCE FROM FRET MEASUREMENTS ON THE ORIENTATION OF THE CAV1.1 II-III LOOP RELATIVE TO RYR1. Danielle M. Heebner , Matthew J. Graham, Daniel J. Enders, Luyi Gao, Kurt G. Beam 60-Plat 8:45 am RESOLVING CALMODULIN-RYR2 CONFORMATIONAL DYNAMICS BY REAL-TIME FRET IN PERMEABILIZED AND INTACT CARDIAC MYOCYTES. Victor Alencar Almeida , Christopher Y. Ko, Renee A. Gorman, Peter H. Backx, Robyn T. Rebbeck, Donald M. Bers 61-Plat 9:00 am ION FLUX CAUSES THE RELEASE OF EXTRACELLULAR VESICLES FROM NEURONAL CELLS. Greta E. Schmidt , Suzanne F. Scarlata 62-Plat 9:15 am CORTICAL ADHESION-DIRECTED MEMBRANE FLOW ACTIVATES ULTRA FAST ENDOCYTOSIS IN NEURONS. Yingwen Huang, Ioana C. Butu, Ben O’Shaughnessy 63-Plat 9:30 am SUB-SARCOMERIC SPATIAL MULTIOMICS REVEALS DISTINCT ORGANIZA TION OF EXCITATION-CONTRACTION COUPLING MRNA TRANSLATION. Bennett Yunker , Vladimir Bogdanov, Yiran Guo, Galina Sakuta, Juan I.E. Mariangelo, Sandor Gyorke 64-Plat 9:45 am Travel Award Winner LRRC26-ASSOCIATED BK CHANNELS REGULATE MEMBRANE POTENTIAL AND INTRACELLULAR CALCIUM SIGNALING IN COLONIC GOBLET CELLS. Gardenia Payne Deliz , Pedro L Martinez-Espinosa, Reena Kumari, Xiao Ming Xia, Matthew Ciorba, Vivian Gonzalez-Perez 65-FlashTalk 10:00 am ELUCIDATION OF THE MEMBRANE BINDING PROPERTIES OF JUNC TOPHILIN. Zehua Shangguan , Marta Campiglio, Marc Yehya, Manu Ben-Johny, Nazzareno D’Avanzo, Filip Van Petegem Steven E. Cala, Wayne State University, USA Michele Cervellera, Ghent University, Belgium 58-Plat 8:15 am

66-FlashTalk 10:05 am A NOVEL MECHANISM FOR LONG DISTANCE CALCIUM SIGNALING WITHOUT GAP JUNCTIONS. Benjamin M. Goykadosh , Vasuretha Chan dar, Harikrishnan Parameswaran 67-FlashTalk 10:10 am CALSEQUESTRIN-2 PHOSPHORYLATION BY PROTEIN KINASE CK2 PRE DICTS AN IMPORTANT NEW FUNCTION IN THE CYTOSOL. Steven E. Cala Platform Systems Biophysics 8:15 am - 10:15 am, Room 212/213/214 Co-Chairs Shankar Mukherji, Washington University in Saint Louis, USA Tianyu Wu, University of Illinois, Urbana-Champaign, USA 68-Plat 8:15 am MODELING COEVOLUTIONARY DYNAMICS OF CRISPR IMMUNITY AND VIRAL DIVERSITY. Mehmet Velat Inci , Herbert Levine 69-Plat 8:30 am SPATIAL HETEROGENEITY ALTERS THE DYNAMICS OF THE YEAST GALAC TOSE SWITCH: INSIGHTS FROM 4D RDME-ODE HYBRID SIMULATIONS. Tianyu Wu , Marie-Christin Spindler, Abner Apsley, Henry Li, Zane R. Thornburg, Julia Mahamid, Zaida Luthey-Schulten 70-Plat 8:45 am WHOLE-CELL PARTICLE-BASED DIGITAL TWIN SIMULATIONS FROM LAT TICE LIGHT-SHEET MICROSCOPY DATA. Eric C. Arkfeld , Zichen Wang, Hiroyuki Hakozaki, Johannes Schoeneberg 71-Plat 9:00 am FROM DECAY TO RHYTHM: SUSTAINED BIOLOGICAL OSCILLATORS RE QUIRE MORE THAN CHEMISTRY ALONE. Yufei Wu , Sean Sun 72-Plat 9:15 am THERMOGENETIC TOOLS FOR PROGRAMMABLE PROTEIN FUNCTION IN CELLS. Cong Q. Vu , Satoshi Arai 73-Plat 9:30 am BUILDING THE CELL FROM UNRELIABLE PARTS: COORDINATING STO CHASTIC ORGANELLE BIOGENESIS WITH CELLULAR GROWTH. Shankar Mukherji 74-Plat 9:45 am DIRECT OBSERVATION OF SINGLE ENDOCYTIC EVENTS AND INTRACEL LULAR TRAFFICKING OF A BRAIN-PENETRATING FAB USING 4D IMAG ING. Stavroula Margaritaki , Franziska Schöppe, Thor Christian Møller, Nikos S. Hatzakis 75-FlashTalk 10:00 am LOSS OF SERCA-REGULATORY MICROPEPTIDE ELN ENHANCES OXIDATIVE STRESS AND INFLAMMATORY SIGNALING IN VASCULAR TISSUES. Seth L. Robia, Rhys A. Smith 76-FlashTalk 10:05 am A RECEPTOR INACTIVATION MODEL FOR HABITUATION IN THE SINGLE CELL STENTOR COERULEUS. Deepa Rajan , Wallace Marshall 77-FlashTalk 10:10 am SPEEDING UP A MECHANISTIC MODEL DESCRIBING THE SENSORY CELLS OF HEARING USING MACHINE LEARNING. Joseph M. Marcinik , Daibhid O Maoileidigh

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CPOW Committee Meeting 8:30 am - 10:30 am, Room 312

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