BPS2026 Program Book

Cellular and Molecular (Boards LB94 - LB101) L2555-Pos Board LB94 BEHAVIORAL AND MITOCHONDRIAL EFFECTS OF EARLY NICOTINE EXPO SURE IN ZEBRAFISH. Arushi Patel L2556-Pos Board LB95 SERA FROM LONG-COVID PATIENTS EXCITES CA1 PYRAMIDAL NEU RONS OF HIPPOCAMPUS, BUT NOT LATERAL SEPTUM NEURONS, IN A MANNER SIMILAR TO MUSCARINIC ACHR AGONISTS. JinBin Tian, Angel Nunez-Correa, Fabio Vigil, Levgen Khomula, Michael X. Zhu, Monica Verduzco-Gutierrez, Victor De La Rosa, Isabel Muzzio, Mark S. Shapiro L2557-Pos Board LB96 DISSECTING THE ROLE OF COPPER AND PRION PROTEIN IN DIFFEREN TIATION, MATURATION, AND NEURODEGENERATION OF DORSAL FORE BRAIN ORGANOIDS. Yanahi Posadas , Simote Foliaki, Katie Williams, Bradley R. Groveman, Brent Race, Tina Thomas, Cathryn Haigh L2558-Pos Board LB97 USING C. ELEGANS TO UNDERSTAND HOW PATIENT CALCIUM CHANNEL MUTATIONS IMPACT SYNAPTIC TRANSMISSION. Michael Krawchuk L2559-Pos Board LB98 LOCOMOTION-ASSOCIATED TRANSIENTS IN BRAIN ENERGY METABO LISM IN AWAKE MICE. Philipp Machler , Yusuke Nasu, David Kleinfeld L2560-Pos Board LB99 CALCIUM MODULATES SYNAPTIC TIMING PRECISION IN A RATE-DEPEN DENT MANNER. Guanyu Li L2561-Pos Board LB100 TARGETING REST-SCP1 SIGNALING TO ALLEVIATE NEUROPATHIC PAIN. Frederick Jones, Shihab S. Shah , Emanuele Sher, Nikita Gamper L2562-Pos Board LB101 COMPUTATIONAL MODELING OF EPHAPTIC AND QUANTAL TRANS MISSION IN VESTIBULAR DIMORPHIC SYNAPSES. Aravind Chenrayan Govindaraju, Robert M. Raphael Electron Microscopy (Boards LB102 - LB113) L2563-Pos Board LB102 DIMERIC GOLD NANOPROBES FOR MULTIPLEX MOLECULAR LABELING IN CRYO ELECTRON TOMOGRAPHY. Hoyoung Kim L2564-Pos Board LB103 INFERRING CONFORMATIONAL ENSEMBLES OF FLEXIBLE BIOMOL ECULES FROM CRYO-EM IMAGES USING BIASED MOLECULAR DYNAM ICS SIMULATIONS. Emil Thomasen , David Silva-Sánchez, Minhuan Li, Geoffrey Woollard, Pilar Cossio L2565-Pos Board LB104 QUANTIFYING INTER-DOMAIN MOTION IN CRYO-EM VIA RELATIVE ORIENTATION LANDSCAPE. Chengmin Li , Wooyoung Choi, Yifan Cheng L2566-Pos Board LB105 LOW VOLTAGE ELECTRON MICROSCOPY: AN EMERGING ALTERNATIVE TO HV-TEM FOR THE STRUCTURAL CHARACTERIZATION OF PRO TEINS. Daniela Vieira , Emad Shahnam, Jared Lapkovsky L2567-Pos Board LB106 TOMOVAULT: A DATA MANAGEMENT PLATFORM FOR CRYO-ELECTRON TOMOGRAPHY. Armel Bezault

L2568-Pos Board LB107 HIV-1 ENV REFOLDING PROCEEDS THROUGH ASYMMETRIC INTERMEDI ATES DURING FUSION. Alicia Schaefer , Salah Hassan, George Wanes, Zhuan Qin, Michael W. Grunst, Mohamed Shehata, Lorenzo Casalino, Rommie E. Amaro, José N. Onuchic, Walther Mothes, Paul C. Whitford, Board LB108 FROM SAMPLE TO STRUCTURE: HANDS-ON CRYO-EM TRAINING AT THE PACIFIC NORTHWEST CENTER FOR CRYO-EM. Marzia Miletto , Omar Da vulcu, Marcelo De Farias, Rose Marie Haynes, Nancy Meyer, Sean Mul ligan, Janette Myers, Vamseedhar Rayaprolu, Kjirsten Wheeler, James E. Evans, Steve Reichow, Claudia S. López L2570-Pos Board LB109 LARGE VOLUME CONTEXTUAL CRYO-IMAGING OF MOUSE HIPPOCAM PAL LAYERS. Yusheng Qian , Lydia-Marie Joubert, Yang Xu, Oleg Klykov L2571-Pos Board LB110 CRYO-EM STRUCTURAL INVESTIGATIONS INTO COLLAGENOUS ASSEM BLIES. Mark A. Kreutzberger , Le Tracy Yu, Carson Cole, Ryan Makin, Bradley Gelfand, Jeffrey Hartgerink, Edward H. Egelman L2572-Pos Board LB111 USING VIRUS-LIKE-PARTICLES (VLPS) IN E.COLI AS A NEW BENCHMARK FOR CRYO-ELECTRON TOMOGRAPHY. Mallak Ali , Tahiti Dutta, Mykhailo Kopylov, Joshua Hutchings, Nikki Jean, Noeli Paz Soldan, Anchi Cheng, Pavel Olshin, Yue Yu, Garrett Greenan, Elizabeth Montabana, M.G. Finn, Mohammadreza Paraan, Matthias Haury, Bridget Carragher, David Agard L2573-Pos Board LB112 A STRUCTURAL ANALYSIS OF THE HOST/PHAGE INFECTION CYCLE OF PSSP7 REVEALED BY CRYO-ELECTRON MICROSCOPY AND TOMOG RAPHY. Amar D. Parvate , Pavlo Bohyutski, Trevor H. Moser, Doo Nam Kim, August George, Natalie C. Sadler, Connah Johnson, Lylia Gomez, Chengxuan Li, Katharine Baldwin, Margaret Cheung, James E. Evans L2574-Pos Board LB113 A VIRAL SPIKE BENCHMARK FOR RESOLUTION LIMITS IN SUBTOMO GRAM AVERAGING. Daniel Asarnow , Cameron Stewart, David Veesler Bioengineering (Boards LB114 - LB117) L2575-Pos Board LB114 STRUCTURE-FORECE RELATIONSHIPS IN CARDIAC LAMINAR TISSUES BENCHMARKING HUMAN IPSC-DERIVED CARDIOMYOCYTES AGAINST NEONATAL RAT MYOCYTES. Yongjun Jang , Kevin Shani, Anna Clouvel Gervaiseau, Maksymilian Prondzynski, Simone Nuebling, Christopher J. Shin, Yichong Wang, Giulio Ciucci, Michio Kawai, Yoonseo Lee, Griffin Radtke, Durgesh Bonde, William T. Pu, Kevin Kit Parker L2576-Pos Board LB115 GUT-ON-A-CHIP PLATFORM REFLECTING REGIONAL INTESTINAL DIFFER ENCES FOR DIETARY XENOBIOTIC EVALUATION. Hyojeong Lee , Huisoo Jang, Tae-Joon Jeon, Sun Min Kim L2577-Pos Board LB116 A CHIP-SCALE INTEGRATED, OPTICALLY POWERED NEURAL MICRO STIMULATOR FOR MINIMALLY INVASIVE DEEP-BRAIN MODULA TION. Gwangho Choi , Joonyoung Lim, Yungeol Nam, Sangjun Gim, Yoon-kyu Song L2578-Pos Board LB117 THE MECHANICAL AND BIOLOGICAL EVOLUTION OF PRESSURE ULCER FORMATION AND HEALING IN MICE. Chien-Yu Lin , Shreya Sreedhar, Colton J. Kostelnik, Matthew J. Lohr, Alberto Madariaga, Adrián Buganza Tepole, Manuel K. Rausch Wenwei Li L2569-Pos

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