BPS2026 Program Book

Platform Computational Biophysics: Molecular Dynamics, AI/ML, and Bioinformatics II 8:15 am - 10:15 am, Room 209/210/211 Co-Chairs Erin Angelini, Allen Institute for Cell Science, USA Luke Evans, Flatiron Institute, USA 694-Plat 8:15 am A DYNAMICAL SYSTEMS FRAMEWORK APPLIED TO LIVE CELL IMAGING UNCOVERS A FIRST-ORDER PHASE TRANSITION BETWEEN MORPHOL OGY-BASED CELL STATES. Erin Angelini , Rebecca Zaunbrecher, Ellen Adams, Tiffany Barszczewski, Antoine Borensztejn, Julie Dixon, Renske Dupar, Jacqueline Edmonds, Maxwell Hedayati, Caroline Hookway, Chantelle Leveille, Jacob McCarley, Benji Morris, Gouthamrajan Nada rajan, Serge Parent, Emmanuel Sanchez, John Paul Thottam, Jessica Yu,. Allen Institute for Cell Science, Jin Wang, Gokhan Dalgin, Julie Theriot, Susanne M. Rafelski, Matheus Palhares Viana 695-Plat 8:30 am RECONSTRUCTING CARDIAC DYNAMICS AND MODEL PARAMETERS US ING DATA-ASSIMILATION. Mario J. Mendez , Seth H. Weinberg 2378-Pos 8:45 am Travel Award Winner MODEL-BASED IMAGE ANALYSIS PIPELINE FOR LIVE CELL IMAGING OF CELL-CYCLE AND KINASE ACTIVITY DYNAMICS. Anand P. Singh , Zeliha Kilic, Daniel Terry, Scott C. Blanchard 697-Plat 9:00 am TOWARD A UNIFIED COMPUTATIONAL PLATFORM FOR INTEGRATING BIOPHYSICAL EXPERIMENTS AND SIMULATION MODELS. Sandra Byju , Fabrizio Marinelli 698-Plat 9:15 am PARSIMONIOUS RECOVERY OF CRYO-EM ENSEMBLE PROBABILITIES. Luke Evans , Robert Gower, Aditya Rangan, Pilar Cossio 699-Plat 9:30 am RECOVERING EQUILIBRIUM STATISTICS FROM VITRIFIED CRYO-EM SAM PLES. Louis G. Smith , Robert Clark, Miro A. Astore, Sonya M. Hanson 700-Plat 9:45 am PICKET: AN UNSUPERVISED METHOD FOR LOCALIZING MACROMOL ECULES IN CRYO-ELECTRON TOMOGRAMS. Shreyas M. Arvindekar, Omkar Golatkar, Shruthi Viswanath 701-FlashTalk 10:00 am SINGLE MICRORNA IDENTIFICATION IN LOW CONCENTRATION SAMPLES WITH NANOPORE MEASUREMENT AND TRANSFER LEARNING. Soma Emura 702-FlashTalk 10:05 am BIOBRAIN: NATURAL LANGUAGE INTELLIGENCE FRAMEWORK FOR AUTONOMOUS MICROSCOPY DATA ANALYSIS & VISUALIZATION. Konstantinos Tsolakidis , Steen W.B. Bender, Nikos S. Hatzakis 703-FlashTalk 10:10 am ALL THE DATA WE CANNOT SEE: MAXIMISING INFORMATION EXTRAC TION FROM FLUORESCENCE LOCALISATION IMAGING WITH PHOTO BLEACHING USING REVERSIBLE JUMP MCMC AND HIDDEN MARKOV MODELLING. Emily M. Gribbin , Benjamin M. Davis, Daniel J. Rolfe, Hannah J. Mitchell

Platform Methodological Developments in Biophysics 8:15 am - 10:15 am, Room 212/213/214 Co-Chairs Sam Carey, University of Wisconsin-Madison, USA Joshua Ziarek, Northwestern University, USA 704-Plat 8:15 am DESIGNING RELAXATION-OPTIMIZED 19 F- 13 C PROBES FOR MULTIDIMEN SIONAL NMR. Joshua Ziarek 705-Plat 8:30 am NUCLEAR-SPIN HYPERPOLARIZATION OF BIOMOLECULES ON AN 80 MHZ BENCHTOP NMR SPECTROMETER. Sam C. Carey , Anubhab Halder, Ummay Mahfuza Shapla, Catherine F.M. Clewett, Silvia Cavagnero 706-Plat 8:45 am MULTIMODAL HOLOTOMOGRAPHY ENABLES CORRELATIVE 3D REFRAC TIVE INDEX AND FLUORESCENCE IMAGING FOR BACTERIAL INFECTION STUDIES. Ziyang Yu , Mingyang Liang, Thaisa Luup Carvalho Kannen, Thorsten Wohland, Christopher M. Yip 707-Plat 9:00 am CANCELED Travel Award Winner HIGH RESOLUTION ELECTRON DENSITY OF PROTEIN-LIGAND COMPLEX ES FROM SOLUTION SCATTERING. Sarah Chamberlain , Thomas D. Grant 708-Plat 9:15 am LABEL-FREE HIGH-PRECISION SINGLE-MOLECULE IMAGING SYSTEM FOR PROBING NANOSCALE MOTION OF ENZYMES. Masato Sawa , Yasushi Okada 709-Plat 9:30 am Travel Award Winner ENGINEERING FAR-RED GENETICALLY ENCODED VOLTAGE INDICATORS FOR IN VIVO IMAGING. Flavia Maria Galeazzi , Eric W. Salter, Mohamed S. Abdelfattah, Ahmed S. Abdelfattah 710-Plat 9:45 am Travel Award Winner INTEGRATING EXPERIMENTAL DATA WITH AI TO GENERATE PHYSIOLOGI CALLY RELEVANT PROTEIN ENSEMBLES. Feng Yu , Stephanie Prince, Andrew Tritt, Kanupriya Pande, Greg L. Hura, Oliver Ruebel, Susan E. Tsutakawa 711-FlashTalk 10:00 am IGLU3FAST AND IGLU3SLOW, IMPROVED FLUORESCENT REPORTERS FOR DETECTION OF SPONTANEOUS GLUTAMATE ACTIVITY IN THE BRAIN. Oanh Tran, Sara Bertelli, Holly J. Hughes, Laura Rocha Labres, Tom D. Carter, Andrew J. Plested, Katalin Torok 712-FlashTalk 10:05 am BIOPHYSICAL EPR USING SUPERCONDUCTING RESONATORS. Troy Borneman 713-FlashTalk 10:10 am Travel Award Winner ATOMIC-LEVEL INFORMATION FROM SWAXS: QUANTIFYING UNCER TAINTY IN BIOLOGICAL MODELS. Patrick K. Oduro , Jitendra Singh, Sarah Chamberlain, Thomas D. Grant

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