BPS2026 Program Book

Symposium The Ins-and-Outs of Mitochondrial Ions and Metabolites 10:45 am - 12:45 pm, Room 201/202/203 Chair Ming-Feng Tsai, University of Virginia, USA 722-Symp 10:45 am MITOCHONDRIAL TRANSPORTERS AND THE CONTROL OF CELLULAR METABOLISM. Nora Kory 723-Symp 11:15 am CRYO-EM OF MEMBRANE PROTEIN COMPLEXES FROM AND WITHIN MITOCHONDRIA. Werner Kuehlbrandt 724-SympSelect 11:45 pm CONFORMATIONAL DYNAMICS IN THE MITOCHONDRIAL PYRUVATE CARRIER. Maximilian Sichrovsky, Denis Lacabanne, Jonathan J. Rupre cht, Jessica J. Rana, Klaudia Stanik, Mariangela Dionysopoulou, Alice P. Sowton, Martin S. King, Scott A. Jones, Lee Cooper, Steven W. Hardwick, Giulia Paris, Dimitri Y. Chirgadze, Shujing Ding, Ian M. Fearnley, Shane M. Palmer, Els Pardon, Jan Steyaert, Vanessa Leone , Lucy R. Forrest, Sotiria Tavoulari, Edmund R. Kunji 725-Symp 12:15 pm MOLECULAR MECHANISM OF MITOCHONDRIAL CALCIUM TRANSPORT. Ming-Feng Tsai Platform Voltage Gated Channels 10:45 am - 12:45 pm, Room 204/205/206 Co-Chairs THE ROLE OF THE C-TERMINAL DOMAIN IN NAVSP1 CHANNEL MODU LATION BY TEMPERATURE. Angel Zavala Custodio, Carlos Gonzalez Leon, Vikram K. Mulligan, Gerhard Hummer, Sonya M. Hanson, Andres Jara Oseguera 727-Plat 11:00 am CA V 3.1-CHANNEL VOLTAGE-SENSING DOMAINS ACTIVATE NEAR THE RESTING MEMBRANE POTENTIAL. Marina Angelini , Moira McVicar, Savana Maxfield, Ania Sokolowska, Sanjana Narang, Kyle Scranton, Sumeyye Suheda Yasarbas, Nicoletta Savalli, Scott A. John, Andreas Schwingshackl, Alan Neely, Antonios Pantazis, Michela Ottolia, Riccardo Olcese 728-Plat 11:15 am UNRAVELING THE COMPLEXITY OF DRUG BINDING TO THE HERG CHAN NEL USING A COMPUTATIONAL APPROACH: FROM CHANNEL STATES TO PATIENT-SPECIFIC VARIANTS. Jiaying Yan , Sophia Brunkow, Kyle C. Rouen, Khoa Ngo, Igor V. Vorobyov 729-Plat 11:30 am RESPONSIVE KINETIC MODELING AND ELECTROPHYSIOLOGY: CARVING A PATHWAY TO MECHANISTIC INSIGHT. Jessica M. Swanson Guillermo J. Perez, University of Girona, USA Jessica M. Swanson, University of Utah, USA 726-Plat 10:45 am

730-Plat 11:45 am CHANSPORTER INTERACTIONS LINK AN AE3 MUTATION TO SHORT QT SYNDROME. David Carreras, Rebecca Martinez-Moreno, Bernat Del Olmo, Oriol Canal Pujol, Ramon Brugada, Fabiana S. Scornik, Guillermo J. Perez 731-Plat 12:00 pm THE CLOSED PORE AND INTERMEDIATE VOLTAGE SENSOR OF THE SHAKER POTASSIUM CHANNEL: ELECTROMECHANICAL COUPLING. Richa Agrawal , Ramon Mendoza Uriarte, Bernardo Pinto Anwandter, Trayder Thomas, Lydia Blachowicz, Francisco Bezanilla, Eduardo Perozo, Benoit Roux 732-Plat 12:15 pm ENGINEERING BK CHANNEL-BASED CALCIUM SENSORS TO PROBE NANODOMAIN CA²⁺ DYNAMICS. Nadya Yanes-Alonso, Lidia Perez-Mar quez, Teresa Minguez Vinas, Diego Alvarez de la Rosa, David Bartolome Martin, Teresa Giraldez 733-FlashTalk 12:30 pm ORTHOGONAL APPROACHES FOR DETERMINING THE STOICHIOMETRY OF HETEROMERIC HERG1A/1B CHANNELS. Sudharsan Kannan , Liliana R. Ernandez, Gail A. Robertson 734-FlashTalk 12:35 pm INVESTIGATING THE ROLE OF VOLTAGE-GATED SODIUM CHANNEL GENE SCN1B IN OXIDATIVE STRESS USING HIPSC DERIVED CARDIOMYOCYTES. Zachary Williams , Erica Marquez, Matthew Loftus, Jonathan R. Silva 735-FlashTalk 12:40 pm CA V 1.2 EF-HAND AND IQ DOMAIN VARIANTS OF UNCERTAIN SIGNIFI CANCE (VUS) AFFECT CA 2+ CURRENT AND CA 2+ HOMEOSTASIS DIFFER ENTLY. Agnieszka Dyrda , Yuan-Chin Lee, Chek-Ying Tan, Chai-Ann Ng, Jamie I. Vandenberg, Filip Van Petegem, Livia C. Hool Platform Biophysics Education 10:45 am - 12:45 pm, Room 207/208 Co-Chairs Lisa J. Lapidus, Michigan State University, USA Linda Shi, University of California, San Diego, USA 736-Plat 10:45 am LEVERAGING ARTIFICIAL INTELLIGENCE FOR BIOPHYSICS EDUCATION. Jacqueline Acres 737-Plat 11:00 am PYBMB: DEVELOPING COMPUTATIONAL LITERACY RESOURCES FOR BIO CHEMISTRY, BIOPHYSICS, AND MOLECULAR BIOLOGY FACULTY. Walter R.P. Novak , Paul A. Craig, Christopher Berndsen, Michael Foster 738-Plat 11:15 am INTRODUCTORY PHYSICS AT THE MOLECULAR AND CELLULAR LEVEL: A NEW CURRICULUM. Lisa J. Lapidus 739-Plat 11:30 am STUDENT UNDERSTANDING OF THE CHEMISTRY AND PHYSICS IN INTRO DUCTORY CHEMISTRY PROBLEMS. Michael E. Green 740-Plat 11:45 am DEVELOPING HANDS-ON RESEARCH PROGRAM AT THE INTERDISCIPLIN ARY INTERSECTION IN PHYSICS, BIOLOGY, AND ENGINEERING FOR HIGH SCHOOL INTERNS. Jiayu Hu, Aspen Lee, Veronica Gomez-Godimez, Padmini Rangamani, Linda Shi 741-Plat 12:00 pm PROPREP: PROPER PROTEIN PREPARATION PREVENTS PROBLEMATIC PRODUCTION SIMULATIONS. Adara Walker, Matthew J. Guberman Pfeffer

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