Biophysical Society 2020 Annual Meeting

Platform Cell Mechanics, Mechanosensing, and Motility 4:00 pm - 6:00 pm, Room 30ABC Co-Chairs Effie Bastounis, University of Washington Stephanie Hoehn, University of Cambridge, United Kingdom 917-plat 4:00 pm QUANTIFYING MOLECULAR FORCES WITH SERIALLY CONNECTED FORCE SENSORS.  Yousif Murad, Adam Yasunaga, Isaac T. Li 918-plat 4:15 pm MORPHOGENESIS IS STRESSFUL - ELASTIC PROPERTIES OF FOLDING CELL SHEETS.  Stephanie S. Hoehn , Pierre A. Haas, Raymond E. Goldstein 919-plat 4:30 pm EMERGENCE OF CELL ORGANIZATION AND PATTERN SENSING FROM ENTROPIC SHAPE FLUCTUATIONS.  Nicholas A. Kurniawan 920-plat 4:45 pm STICK-SLIP DYNAMICS OF MIGRATING CELLS.  Rumi De , Partho Sakha De 921-plat 5:00 pm MECHANICALLY-DRIVEN CELLULAR COMPETITION PROMOTES THE COL- LECTIVE EXTRUSION OF BACTERIA-INFECTED EPITHELIAL CELLS.  Effie E. Bastounis , Prathima Radhakrishnan, Patrik Engström, Francisco Alcalde, Maria Gómez Benito, José M. García Aznar, MatthewWelch, Julie Theriot 922-plat 5:15 pm CORRELATING MECHANICAL AND GENE EXPRESSION DATA ON THE SINGLE CELL LEVEL TO INVESTIGATE METASTASIS.  Katherine M. Young , Congmin Xu, Kelly Ahkee, Roman Mezencev, Peng Qiu, Todd Sulchek 923-plat 5:30 pm DIVERSE MODES OF MOTION OF DICTYOSTELIUM DISCOIDEUM CELLS: CORRELATING CYTOSKELETON ORGANIZATION AND GENERATION OF TRACTION FORCES.  Elisabeth Ghabache , Yuchuan Miao, Peter N. Devreotes, Wouter-Jan Rappel 924-plat 5:45 pm Travel Awardee PLASMA MEMBRANE NANODOMAINS AS AN INTEGRATOR OF SUB- STRATE ENCODED MECHANO-CHEMICAL SIGNALS.  Joseph Mathew Kalappurakkal , Anupama Ambika Anilkumar, Chandrima Patra, Thomas S. van Zanten, Michael P. Sheetz, Satyajit Mayor Platform

906-plat 5:15 pm MONTE CARLO AND MOLECULAR DYNAMICS SIMULATIONS TO EXPLAIN BIOMEMBRANE MESO-PATTERNING BY A COMPOSITION-CURVATURE COUPLING MECHANISM.  Julie Cornet , Matthieu Chavent, Manoel Manghi, Nicolas Destainville 907-plat 5:30 pm MECHANICAL PROPERTIES OF COMPOSITIONALLY ASYMMETRIC MEM- BRANES.  Aparna Sreekumari , Reinhard Lipowsky 908-plat 5:45 pm SUPERRESOLVING THE MEMBRANE TOPOGRAPHY OF LIVE CELLS.  Gabriele Kockelkoren , Line Lauritsen, Christopher Shuttle, Dimitrios Stamou Platform Single-Molecule Spectroscopy 4:00 pm - 6:00 pm, Room 25ABC Co-Chairs Brett Israels, University of Oregon Irina Gophich, NIH 909-plat 4:00 pm QUANTIFYING BINDING AFFINITIES, KINETICS AND STOICHIOMETRY OF BIOMOLECULAR COMPLEXES WITH MASS PHOTOMETRY.  Fabian Soltermann , Veronica Pagnoni, Eric Foley, Martin Galpin, Justin L. Benesch, Weston B. Struwe, Philipp Kukura 910-plat 4:15 pm A MODULAR DNA SCAFFOLD TO STUDY PROTEIN-PROTEIN INTERAC- TIONS AT SINGLE-MOLECULE RESOLUTION.  Dorota N. Kostrz , Hannah K. Wayment-Steele, Jinglong WANG, Maryne Follenfant, Vijay S. Pande, Antoine Triller, Christian G. Specht, Terence R. Strick, Charlie Gosse 911-plat 4:30 pm INVESTIGATION OF LENTIVIRUSES AND THEIR INITIAL CONTACTS WITH CELLS USING REAL-TIME 3D TRACKING.  Jack C. Exell , Shangguo Hou, Courtney C. Johnson, Kevin D. Welsher 912-plat 4:45 pm FAST THREE-COLOR SINGLE-MOLECULE FRET USING CONTINUOUS-WAVE EXCITATION OF DONOR.  Janghyun Yoo , Jae-Yeol Kim, John M. Louis, Irina V. Gopich, Hoi Sung Chung 913-plat 5:00 pm Travel Awardee SINGLE-MOLECULE INVESTIGATION OF CONFORMATIONAL CHANGES IN EPIDERMAL GROWTH FACTOR RECEPTOR.  Raju Regmi , Shwetha Srinivasan, Xingcheng Lin, Steven Quinn, Wei He, Kermit L. Carraway III, Matthew A. Coleman, Bin Zhang, Gabriela Schlau-Cohen 914-plat 5:15 pm SINGLE-MOLECULE DYNAMICS OF THE HUMAN RNA POLYMERASE II PRE- INITIATION COMPLEX.  Rory Cunnison, Oksana Gonchar, Jonathan Grimm, Luke Lavis, Zhengjian Zhang, Andrey G. Revyakin 915-plat 5:30 pm Travel Awardee SUB-MICROSECOND SINGLE-MOLECULE FRET STUDIES OF SINGLE- STRANDED DNA CONFORMATION FLUCTUATIONS MEDIATED BY SINGLE- STRANDED DNA BINDING PROTEINS.  Brett A. Israels , Anson Dang, Peter H. von Hippel, Andrew H. Marcus 916-plat 5:45 pm HIGH GC CONTENT DNA DOES NOT AFFECT PHAGE T4 DNA PACKAGING -- TEST OF A SCRUNCHWORMMODEL FOR PACKAGING MOTOR FUNCTION. Youbin Mo , Nicholas A. Keller, Douglas E. Smith

M O N D A Y

Ligand-gated Channels 4:00 pm - 6:00 pm, Room 31ABC

Co-Chairs Sun Joo Lee, Washington University in St. Louis Erik Lindahl, Stockholm University, Sweden 925-plat 4:00 pm

LIGAND BINDING AND VOLTAGE MODULATION OPEN A CYCLIC-NUCLEO- TIDE GATED ION CHANNEL.  Xiaolong Gao , Chen Fan, Crina M. Nimigean 926-plat 4:15 pm PATCH-CLAMP FLUOROMETRY DEFINES A ROLE FOR SUR1 IN NUCLEO- TIDE INHIBITION OF K ATP CHANNELS.  Samuel Usher, Frances M. Ashcroft, Michael C. Puljung 927-plat 4:30 pm ELUCIDATE THE BINDING MECHANISM OF VARIOUS SETRONS TO 5-HT3AR.  Sandip Basak , Yvonne W. Gicheru, Arvind Kumar, Sudha Chakrapani

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