Biophysical Society 2020 Annual Meeting

Membrane Receptors and Signal Transduction II (Boards B268 - B293) 1200-Pos Board B268 Travel Awardee INNATE ANTIFUNGAL IMMUNE RECEPTOR, DECTIN-1, UNDERGOES LIGAND-INDUCED OLIGOMERIZATION WITH HIGHLY STRUCTURED Β-GLUCANS AND AT FUNGAL CELL CONTACT SITES. Eduardo U. Anaya , Aaron Neumann 1201-Pos Board B269 AN UNUSUAL HYDROGEN-BOND IN THE KDEL RECEPTOR. Zhiyi Wu , Simon Newstead, Philip C. Biggin 1202-Pos Board B270 ACCELERATED MOLECULAR SIMULATIONS OF SUBSTRATE RECOGNITION BY G-SECRETASE. Apurba Bhattarai , Sujan Devkota, Yilong Miao, Michael S. Wolfe, Sanjay Bhattarai 1203-Pos Board B271 MODELING THE BINDING MECHANISM OF A T CELL RECEPTOR AND MA- JOR HISTOCOMPATIBILITY COMPLEX. Erin Groth , Cory M. Ayres, Brian M. Baker, Steven A. Corcelli 1204-Pos Board B272 HOW THE T CELL SIGNALING NETWORK PROCESSES INFORMATION TO DISCRIMINATE BETWEEN SELF AND COGNATE LIGANDS. Raman S. Ganti , Wan-Lin Lo, Darren McAffee, Jay T. Groves, Arthur Weiss, Arup K. Chakraborty 1205-Pos Board B273 SPATIAL REQUIREMENTS FOR T-CELL RECEPTOR TRIGGERING PROBED VIA FUNCTIONALIZED DNA ORIGAMI PLATFORMS.  Joschka P. Hellmeier , Rene Platzer, Andreas Karner, Victoria Motsch, Victor Bamieh, Johannes Preiner, Mario O. Brameshuber, Hannes Stockinger, Gerhard J. Schütz, Johannes B. Huppa, Eva Sevcsik 1206-Pos Board B274 MAGNESIUM DEFICIENCY CAUSES REVERSIBLE DIASTOLIC AND SYSTOLIC CARDIOMYOPATHY. Man Liu , Hong Liu, An Xie, Gyeoung-Jin Kang, Feng Feng, Xiaoxu Zhou, Yang Zhao, Samuel C. Dudley 1207-Pos Board B275 COMPARATIVE ANALYSIS OF THE RESIDUE CO-EVOLUTION OF THE DNA-BINDING RESPONSE REGULATOR SUBFAMILIES. Mayu Shibata , Xingcheng Lin, Ryan R. Cheng, Kei Yura, José N. Onuchic 1208-Pos Board B276 SOLUBLE ADENYLYL CYCLASE AT THE NANOSCALE: IMAGING AND FUNC- TION IN HEART. Liron Boyman , Konstantinos Lefkimmiatis, Tullio Pozzan, W. Jonathan Lederer, Maura Greiser 1209-Pos Board B277 IQGAP1 SCAFFOLDING CONNECTS EGFR AND PHOSPHOINOSITIDE SIGNALING TO CYTOSKELETAL REORGANIZATION. V Siddartha Yerramilli , Alonzo H. Ross, Jessica Reisinger, Karin Plante, Suzanne F. Scarlata, Arne Gericke 1210-Pos Board B278 EXPANDING NUMBER AND BRIGHTNESS TO DETERMINE THE OLIGO- MER SIZE OF MEMBRANE PROTEINS IN LIVE CELLS AS A FUNCTION OF CONCENTRATION. Michael D. Paul , Yi Zuo, Randall Rainwater, Luo Gu, Kalina Hristova 1211-Pos Board B279 Travel Awardee PAIR CORRELATION ANALYSIS REVEALS BARRIERS TO NATURAL KILLER CELL RECEPTOR MOTION AT THE SYNAPSE. Per Niklas Hedde , Elina Staaf, Sunitha Bagawath Singh, Sofia Johansson, Enrico Gratton

1212-Pos Travel Awardee COACTION OF ELECTROSTATIC AND HYDROPHOBIC INTERACTIONS IN SIGNALING: DYNAMIC CONSTRAINTS ON DISORDERED TRKA JUXTA- MEMBRANE DOMAIN. Zichen Wang , Huaxun Fan, Xiao Hu, John Khamo, Jiajie Diao, Kai Zhang, Taras V. Pogorelov 1213-Pos Board B281 Travel Awardee DNA PROBES THAT STORE MECHANICAL INFORMATION REVEAL TRAN- SIENT PICONEWTON FORCES APPLIED BY T CELLS. Rong Ma , Anna V. Kellner, Victor Pui-Yan Ma, Hanquan Su, Brendan R. Deal, Joshua Brock- man, Khalid Salaita 1214-Pos Board B282 EXPANSION MICROSCOPY REVEALS THAT CD45 IS EXCLUDED FROM THE TIPS OF MICROVILLI IN T AND B LYMPHOCYTES. Yunmin Jung , Lai Wen, Sara McArdle, Klaus Ley 1215-Pos Board B283 PLASMA MEMBRANE ORGANIZATION IS POISED TO MEDIATE STIMU- LATED TRANSMEMBRANE SIGNALING. Nirmalya Bag , David A. Holowka, Barbara A. Baird 1216-Pos Board B284 MECHANICAL STRESS MAY IMPACT THE FORMATION OF STRESS GRAN- ULES. Androniqi Qifti , Suzanne F. Scarlata 1217-Pos Board B285 DISCRETE-STATE STOCHASTIC MODELING OF T-CELL ACTIVATION.  Hamid Teimouri , Anatoly B. Kolomeisky 1218-Pos Board B286 THE FORMATION OF LAT PROTEIN CONDENSATES IN RESPONSE TO SINGLE PMHC-TCR BINDING EVENTS. Darren McAffee , Shalini Low-Nam, Jenny J. Lin, Scott D. Hansen, Steven Alvarez, Jay T. Groves 1219-Pos Board B287 HOW GROWTH FACTOR RECEPTOR CLUSTERING PROMOTES DOWN- STREAM SIGNALING. Kelvin J. Peterson , Leslie M. Loew 1220-Pos Board B288 PI 4-KINASE AND PIP 5-KINASE COOPERATE TO REPLENISH PTDINS(4,5) P 2 AFTER RECEPTOR-MEDIATED DEPLETION.  Jill B. Jensen , Lizbeth de la Cruz, Alexis Traynor-Kaplan, Bertil Hille 1221-Pos Board B289 GENETIC BIOSENSORS FOR REAL TIME MONITORING OF THE ACTIVA- TION OF SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION (STAT). Aisha M. Attar 1222-Pos Board B290 RHOA MEDIATED JUXTACRINE REGULATION OF GLUCAGON SECRE- TION. Yong Hee Chung , David W. Piston 1223-Pos Board B291 LATTICE LIGHT-SHEET MICROSCOPY MULTI-DIMENSIONAL ANALYSES (LAMDA) OF T-CELL RECEPTOR DYNAMICS PREDICT T-CELL SIGNALING STATES.  Jun Huang 1224-Pos Board B292 REGULATION OF DHHC5 ENZYMATIC ACTIVITY IN CARDIOMYOCYTES.  Jie Chen , Autumn N. Marsden, C. Anthony Scott, Askar M. Akimzhanov, Darren F. Boehning 1225-Pos Board B293 LIPID REMODELLING IN CD36 NANOCLUSTERS PROMOTES FYN ACTIVA- TION IN RESPONSE TO THROMBOSPONDIN-1. Nicolas Touret , Swai Mon Khaing Board B280

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