Biophysical Society 2020 Annual Meeting

1377-Pos Board B445 BIOMECHANICS OF JAM-C-MEDIATED NEUTROPHIL REVERSE TRANSEN- DOTHELIAL MIGRATION. Yi-Ting Yeh , Ricardo Serrano, Ernesto Criado- Hidalgo, Juan Carlos del Álamo, Juan Carlos Lasheras 1378-Pos Board B446 BINDING OF RAS TO PI3K: MEASURING BINDING AFFINITY, AND THE EFFECTS OF DISEASE-LINKED H-RAS MUTATIONS ON AFFINITY. G Hayden Swisher , Nicholas J. Cordaro, Justin G. Martyr, Annette H. Erbse, Johna- thon H. Hannan, Emily M. Kibby, Joseph J. Falke 1379-Pos Board B447 EFFECT OF EXTRACELLULAR MATRIX STIFFNESS GRADIENT ON DUROTAX- IS MOTION AND CELL MIGRATION OF CELLS USING DYNAMIC CELLULAR FINITE ELEMENT MODEL (DYCELFEM). Pourya Delafrouz , Jieling Zhao, Wei Tian, Jie Liang 1380-Pos Board B448 PTEN-PI(4,5)P 2 POSITIVE FEEDBACK MECHANISM FOR STABILIZING ASYM- METRIC PI(3,4,5)P 3 LOCALIZATION IN MIGRATING CELL. Daisuke Yoshioka , Seiya Fukushima, Hiroyasu Koteishi, Daichi Okuno, Toru Ide, Satomi Matsuoka, Masahiro Ueda 1381-Pos Board B449 DIRECT FORCE MEASUREMENT OF THE PANC-1’S TRACTION FORCE. Takeshi Sakamoto , Yuwen Mei, Justin Raupp 1382-Pos Board B450 CELL MECHANICS AND INVASION ARE INFLUENCED BY ST6GAL-I MEDI- ATED SIALYLATION OF EGFR. Tejeshwar C. Rao , Reena R. Beggs, Katie L. Dietz, Victor Pui-Yan Ma, Khalid Salaita, Susan L. Bellis, Alexa L. Matthey- ses 1383-Pos Board B451 BEYOND A CRITICAL STRAIN, LAMIN-A DILATES AND NUCLEI RUPTURE AT SITES OF HIGH CURVATURE. Charlotte R. Pfeifer , Michael P. Tobin, Lizeth Lopez, Emma G. Ricci-De Lucca, Keiann T. Simon, Dennis E. Discher 1384-Pos Board B452 UNDERSTANDING MECHANICAL EFFECTS ON THE DYNAMICS OF NA- SCENT ADHESIONS. Laurent MacKay , Etienne Lehman, Anmar Khadra 1385-Pos Board B453 LIPID DROPLETS DEFORM NUCLEUS AND CAUSE MISLOCALIZATION OF DNA REPAIR FACTORS.  Irena L. Ivanovska , Michael P. Tobin, Charlotte R. Pfeifer, Dennis E. Discher 1386-Pos Board B454 ROS INDUCED CELL MECHANICAL ALTERATIONS IN SUSPENSION AND ADHERENT CELLS. Yesaswini Komaragiri 1387-Pos Board B455 THE DYNAMICS OF PROTEIN TRANSLATION IN THE PROCESS OF CELLULAR ADHESION. Alexia Caillier , Jonathan Bergeman, Marc-Étienne Huot 1388-Pos Board B456 UTILIZING MOLECULAR DYNAMICS SIMULATIONS TO PROBE THE RELEASE OF SIGNAL FACTORS FROM THE ADHERENS JUNCTION. Brandon L. Neel , Marcos M. Sotomayor 1389-Pos Board B457 GENETICALLY ENGINEERED MYOBLASTS FOR MEASURING NUCLEAR LAMINA STRESS. Thomas M. Suchyna , Frederick Sachs, Fanjie Meng, Wilma A. Hofmann 1390-Pos Board B458 Travel Awardee SUPER-RESOLVED MEASUREMENT OF PICONEWTON RECEPTOR FORCES VIA TENSION-PAINT.  Joshua M. Brockman , Hanquan Su, Alexa L. Mat- theyses, Yonggang Ke, Khalid Salaita

1391-Pos Board B459 PHYSICAL DETERMINANTS OF PARTICLE UPTAKE AND TRANSPORT DURING PHAGOCYTOSIS. Steve Keller, Simon Wieland, Wolfgang Gross, Konrad Berghoff, David Gitschier, Manuel Eisentraut, Holger Kress 1392-Pos Board B460 A SIDE-VIEW ON NUCLEAR MECHANICS: COMBINED ATOMIC FORCE MI- CROSCOPY AND LIGHT SHEET MICROSCOPY INFORM CHROMATIN’S ROLE IN REGULATING NUCLEAR MORPHOLOGY. Chad Hobson , Evan F. Nelsen, Joe Hsiao, Megan E. Kern, Andrew Stephens, E. Timothy O’Brien, Michael R. Falvo, Richard Superfine Genetic Regulatory Systems (Boards B461 - B467) 1393-Pos Board B461 AGE-DEPENDENT PROTEIN DEGRADATION MODULATES NOISE OF AUTO- REGULATED GENE EXPRESSION.  Ji-Hyun Kim , Jaeyoung Sung 1394-Pos Board B462 PROBABILITY LANDSCAPE OF COUPLED EPIGENETIC AND GENETIC NET- WORK WITH EDDY-LIKE PROBABILITY CURRENTS. Bhaswati Bhattacharyya , Masaki Sasai 1395-Pos Board B463 REPLICATION INITIATION CONTROL IN E. COLI. Dongyang Li , Suckjoon Jun 1396-Pos Board B464 IN SITU SINGLE-MOLECULE DYNAMICS OF THE SOS-REPRESSOR LEXA DURING ANTIBIOTIC STRESS. Leonard Schärfen, Milos Tisma, Andreas Hartmann, Michael Schlierf 1397-Pos Board B465 CHEMICAL DYNAMICS IN LIVING CELLS.  Jaeyoung Sung 1398-Pos Board B466 DYSREGULATED CILIARY, AUTOPHAGY AND CELL CYCLING PATHWAYS MANIFEST IN HEPATOBLASTOMA TUMORS REQUIRING LIVER TRANS- PLANTATION - A SYSTEMS BIOLOGY ANALYSIS. Tejaswini Narayanan , Mylarappa Ningappa, Rakesh Sindhi, B. W Higgs, Shankar Subramaniam 1399-Pos Board B467 THE EFFECT OF TIME-DEPENDENT DRIVE AND DELAYED FEEDBACK LOOP IN TWO-DIMENSIONAL GENE REGULATORY NETWORK. Bivash Kaity , Ratan Sarkar, Buddhapriya Chakrabarti, Mithun K. Mitra Computational Neuroscience (Boards B468 - B475) 1400-Pos Board B468 CORRELATING DENDRITIC SPINE GEOMETRY AND CALCIUM TRANSIENTS TO LEARNING AND INFORMATION PROCESSING. Christopher T. Lee , Justin G. Laughlin, Miriam Bell, Michael Holst, Padmini Rangamani 1401-Pos Board B469 PHOSPHAGENS AS ENERGETIC MODERATORS AT CHEMICAL SYNAPSES: A COMPUTATIONAL APPROACH. Sergio Sempertegui , Yaouen Fily, Gregory T. Macleod 1402-Pos Board B470 COMPUTATIONAL MODELLING FRAMEWORK TO STUDY CA 2+ ACTIVA- TION OF SYNAPTIC VESICLE FUSION BY DIFFERENT SYNAPTOTAGMIN ISOFORMS. Christopher A. Norman , Kirill E. Volynski, Shyam S. Krishnaku- mar, Yulia Timofeeva 1403-Pos Board B471 A COMPUTATIONAL MODEL OF PH DYNAMICS WITHIN THE CLEFT OF CONVENTIONAL NEURONAL SYNAPSES. Touhid Feghhi , Gregory T. Ma- cleod, Roberto X. Hernandez, AWC Lau, Michal Stawarski, Jolanta A. Bo- rycz, Zhiyuan Lu, Andrea Aragwal, Ian A. Meinertzhagen, Robert Renden

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