Biophysical Society 2020 Annual Meeting

1404-Pos Board B472 COMPUTATIONAL MODEL OF PARKINSON’S DISEASE PATHOLOGY IN OLFACTORY BULB PREDICTS LOCALIZATION OF NEURAL ACTIVITY AND DISRUPTION TO OSCILLATORY BEHAVIOR. Kendall Berry , Daniel L. Cox 1405-Pos Board B473 PREDICTING THE MORPHOLOGY OF CLASS IV NEURONS FROM THE DYNAMICS OF DENDRITIC GROWTH IN DROSOPHILA . Olivier Trottier , Sabyasachi Sutradhar, Sonal Shree, Jonathon Howard 1406-Pos Board B474 A KINETIC MODEL TO ACCOUNT FOR SELECTIVE TRAPPING OF WEAK BASES INSIDE ACIDIC INTRA-CELLULAR VESICLES. Philip Jordache , William Green, Esmael Haddadian 1407-Pos Board B475 KETONE DIETS CAN REVERSE SOME BRAIN ACTIVITIES THAT ARE LOST IN AGING. Corey Weistuch , Lilianne Mujica-Parodi, Anar Amgalan, Syed Fahad Sultan, Ken A. Dill Neuroscience: Experimental Approaches and Tools (Boards B476 - B488) 1408-Pos Board B476 OPTICAL MODULATION OF RECEPTOR TYROSINE KINASE SIGNALING DUR- ING CELL DIFFERENTIATION AND EMBRYONIC DEVELOPMENT. Savanna R. Sharum, Payel Mondal, Vishnu Krishnamurthy, Kritika Mehta, Huaxun Fan, Jing Yang, Kai Zhang 1409-Pos Board B477 Travel Awardee AN IN VITRO SYSTEM FOR STUDYING NEMATODE MECHANOSENSORY NEURONS.  Joy A. Franco , Alakananda Das, Beth Pruitt, Miriam B. Good- man 1410-Pos Board B478 REPRODUCIBILITY IN MAGNETOGENETICS: SHARING THE LOAD.  Guillaume Duret , Jacob T. Robinson 1411-Pos Board B479 A MATHEMATICAL MODEL OF CEREBRAL CORTICAL FOLDING DEVELOP- MENT. Ahmet Kilinc , Monica K. Hurdal 1412-Pos Board B480 TRANSMEMBRANE HEMOPROTEIN OPTICAL REPORTERS (THORS) FOR MEMBRANE POTENTIAL SENSING. Martin J. Iwanicki , Brian Y. Chow, Christopher C. Moser, Bohdana M. Discher 1413-Pos Board B481 A RATIOMETRIC CALCIUM SENSORS USING BRIGHT GREEN AND RED FLUORESCENT PROTEINS FOR NEURAL CALCIUM IMAGING.  Diming Zhang , Kimberly K. Lennox, Zhijing Zhu, Emily Redington, Yiyang Gong 1414-Pos Board B482 INFLUENCE OF MID-INFRARED LASER IRRADIATION ON MEMBRANE POTENTIALS IN NEURON-LIKE CELLS. Yoshiyuki Shimizu , Gen Takebe, Toyohiko Yamauchi, Tatsuo Dougakiuchi 1415-Pos Board B483 DENSE NEURONAL RECONSTRUCTION THROUGH X-RAY HOLOGRAPHIC NANO-TOMOGRAPHY. Aaron T. Kuan 1416-Pos Board B484 MODULATION OF HUMAN STEM CELL DERIVED NEURON ACTIVITY THROUGH ADDITION OF AN EXTERNAL CONDUCTANCE USING DYNAMIC CLAMP. Brian K. Panama, Leigh Korbel, Brandon Franks, Christine Hickey, Glenna Bett, Randall L. Rasmusson, Mark W. Nowak

1417-Pos Board B485 BIOMECHANICAL STRESSES DUE TO TISSUE MICROMOTION AT THE NEURAL INTERFACE MODULATE INTRACELLULAR MEMBRANE POTEN- TIALS.  Jonathan L. Duncan , Swathy Sampath Kumar, Diane Iradukunda, Arati Sridharan, Jitendran Muthuswamy 1418-Pos Board B486 LIVE CELL STORM STUDIES ON THE PERINEURONAL NET IN CULTURED NEURONS. Duncan L. Nall , Paul R. Selvin 1419-Pos Board B487 EXTERNAL CHARGES INFLUENCE FLUORESCENT PROTEIN PROTON WIRES. Bok Eum Kang , Leticia Leong, Bradley J. Baker 1420-Pos Board B488 EFFECTIVENESS OF THE QUBE IN STUDYING THE RAPIDLY-DESENSITIZING ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR. Sung H. Park 1421-Pos Board B489 WHAT TO EXPECT FROM CRYO-EM AT THE NCCAT NATIONAL SERVICE CENTER. Edward T. Eng , Elina Kopylov, Clinton S. Potter, Bridget Carragher 1422-Pos Board B490 NIH TRANSFORMATIVE HIGH RESOLUTION CRYO-EM AND CRYO-ELEC- TRON TOMOGRAPHY INITIATIVES. Malgorzata Klosek, Mary Ann Wu , Paula F. Flicker, Houmam Araj 1423-Pos Board B491 BOTTOM-UP STRUCTURAL PROTEOMICS: CRYO-EM OF PROTEIN COM- PLEXES ENRICHED FROM THE CELLULAR MILIEU. Chi-Min Ho, Xiaorun Li, Mason Lai, Thomas Terwilliger, Josh Beck, James A. Wohlschlegel, Daniel E. Goldberg, Anthony W.P. Fitzpatrick, Hong Zhou 1424-Pos Board B492 AUTOMATED CRYO-EM STRUCTURE REFINEMENT USING CORRELATION- DRIVEN MOLECULAR DYNAMICS. Andrea C. Vaiana , Maxim Igaev, Lars V. Bock, Carsten Kutzner, Helmut Grubmueller 1425-Pos Board B493 DE NOVO COMPUTATIONAL PROTEIN TERTIARY STRUCTURE MODELING PIPELINE FOR CRYO-EMMAPS OF INTERMEDIATE RESOLUTION. Daisuke Kihara , Genki Terashi, Sai Raghavendra Maddhuri Venkata Subramaniya 1426-Pos Board B494 DAMPED DYNAMICS AS A VALIDATION PLATFORM FOR THE FLEXIBLE REFINEMENT OF ATOMIC MODELS AGAINST CRYO-EMMAPS. Willy R. Wriggers , Vitold E. Galkin, Wade A. Hunter, Julio A. Kovacs 1427-Pos Board B495 Z-CONTRAST ENHANCEMENT FOR SMALL PROTEIN CRYO-EM STRUCTURE DETERMINATION. Adam Oken, Jaeick Lee, Sholto David, Qing Xie, Christo- pher Dennison, James Z. Chen 1428-Pos Board B496 AUTOMATED SEGMENTATION AND CORRECTION OF MISSING-WEDGE ARTIFACTS IN CRYO-ELECTRON TOMOGRAPHY MAPS BY SHAPE-CON- STRAINED DECONVOLUTION. Wade A. Hunter , Julio A. Kovacs, Willy R. Board B497 SEMI-AUTOMATED 3D SEGMENTATION OF HUMAN SKELETAL MUSCLE USING FOCUSED ION BEAM-SCANNING ELECTRON MICROSCOPIC IM- AGES REVEALS NETWORK OF MITOCHONDRIA. Alexander V. Maltsev , Brian Caffrey, Marta Gonzalez-Freire, Lisa Hartnell, Sriram Subramaniam, Luigi Ferrucci Wriggers 1429-Pos Electron Microscopy (Boards B489 - B512)

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