Biophysical Society 2020 Annual Meeting

1430-Pos Board B498 AUTOMATED FIBER DIAMETER AND POROSITY MEASUREMENT OF FI- BRIN CLOTS IN SEM IMAGES. Ali Daraei , Marlien Pieters, Zelda de Lange, Martin Guthold 1431-Pos Board B499 NEURAL MODELING OF EUKARYOTIC CELL ULTRASTRUCTURE OBTAINED FROM 3D ELECTRON MICROSCOPY. Matthew D. Guay , Ruida Cheng, Zeyad A. Emam, Richard D. Leapman 1432-Pos Board B500 ENERGY DISPERSIVE X-RAY SPECTROMETRY IN COMBINATION WITH 3D SEM FACILITATES THE IDENTIFICATION AND SEGMENTATION OF CELLS AND ORGANELLES. Louise Hughes , Stuart Searle, Cheng Cheng, Iain Board B501 QUANTITATIVE IMAGING WITH ELECTRON PROBES OF CULTURED ERYTH- ROBLASTS UNDERGOING ERYTHROPOIESIS. Maria A. Aronova , Seung-Jae Noh, Colleen Byrnes, Guofeng Zhang, Youngchan Kim, Emily R. Meier, Richard D. Leapman 1434-Pos Board B502 DECONSTRUCTING MECHANOTRANSDUCTION CUES FOR A QUANTITA- TIVE IN SITU CELLULAR TOMOGRAPHY WORKFLOW. Guido M. Gaietta , Kai Fuiboon, Valerie M. Weaver, Dorit Hanein 1435-Pos Board B503 CRYO-EM REVEALS ACTIN FILAMENT NUCLEATION BY ACTIVATED ARP2/3 COMPLEX. Saikat Chowdhury , Mohammed H. Shaaban, Brad Nolen 1436-Pos Board B504 ACTIN FILAMENTS IN FLIGHT MUSCLE Z-DISKS OF LETHOCERUS INDICUS S HOW SCREW SYMMETRY, NOT ROTATIONAL SYMMETRY. Fatemeh A. Abbasi Yeganeh , Corinne Summerill, Zhongjun Hu, Hamidreza Rahmani, Dianne Taylor, Kenneth A. Taylor 1437-Pos Board B505 WHY THE INTERACTING HEADS MOTIF IS NOT OBSERVED IN ISOLATED, RELAXED THICK FILAMENTS OF DROSOPHILA MELANOGASTER.  Nadia Daneshparvar , Michael Previs, Thomas O’Leary, Dianne Taylor, Hamidreza Rahmani, Fatemeh Abbasiyeganeh, Kenneth A. Taylor 1438-Pos Board B506 CRYO-EM STRUCTURES OF CHROMATOSOMES CONTAINING HUMAN LINKER HISTONE VARIANTS. Bing-Rui Zhou , Hanqiao Feng, Natalia D. Val, Board B507 STRUCTURE OF THE HELICOBACTER PYLORI CAG TYPE IV SECRETION SYSTEM.  Jeong Min Chung , Michael J. Sheedlo, Anne M. Campbell, Neha Sawhney, Arwen E. Frick-Cheng, D. Borden Lacy, Timothy L. Cover, Melanie D. Ohi 1440-Pos Board B508 STRUCTURE OF THE CYANOBACTERIAL NAD(P)H DEHYDROGENASE-LIKE COMPLEX OF OXYGENIC PHOTOSYNTHESIS. Thomas G. Laughlin , Andrew Bayne, Jean-Francois Trempe, David Savage, Karen Davies 1441-Pos Board B509 TOWARDS AN EFFICIENT RNA DELIVERY SYSTEM - STRUCTURAL INSIGHTS INTO THE INFECTION CYCLE OF SSRNA PHAGES.  Junjie Zhang 1442-Pos Board B510 BILE SALTS ALTER THE MOUSE NOROVIRUS CAPSID CONFORMATION - POSSIBLE IMPLICATIONS FOR CELL ATTACHMENT AND IMMUNE EVA- SION. Alexis Williams , Hong Q. Smith, Michael Sherman, Thomas J. Smith Anderson 1433-Pos Yawen Bai 1439-Pos

1443-Pos Board B511 A NOVEL PACKING FOR A-FORM DNA IN AN ICOSAHEDRAL VIRUS. Feng- bin Wang , Ying Liu, Zhangli Su, James Conway, Stefan Schouten, Mart Krupovic, David Prangishvili, Edward H. Egelman 1444-Pos Board B512 AUTOMATED IDENTIFICATION OF FLEXIBLE MULTIVALENT IDP-BOUND ASSEMBLIES IN ELECTRON MICROGRAPHS. Barmak Mostofian , Russell McFarland, Elisar J. Barbar, Steve L. Reichow, Daniel M. Zuckerman

M O N D A Y

Molecular Dynamics II (Boards B513 - B538)

1445-Pos Board B513 CAN SIMULATIONS BE RECYCLED TO BENCHMARK RNA FORCE FIELDS. Louis G. Smith , Scott D. Kennedy, Douglas H. Turner, Alan Gross- field, David H. Mathews 1446-Pos Board B514 COARSE-GRAINED SIMULATION OF DNA-POLYETHYLENIMINE AGGREGA- TION AT ENDOSOMAL PH: IMPLICATIONS TO NANOPARTICLE DISSOCIA- TION. Subhamoy Mahajan , Tian Tang 1447-Pos Board B515 A LARGE SCALE SIMULATION OF MUCUS. Arlette R. Baljon , Jon Parsons 1448-Pos Board B516 PHOSPHORYLATION OF INTRINSICALLY DISORDERED REGIONS WITHIN THE GENOME. Akshay Sridhar , Guillem Portella, Modesto Orozco, Rosana Collepardo-Guevara 1449-Pos Board B517 RECONSTRUCTION OF ARNT PAS-B UNFOLDING PATHS BY STEERED MD AND ARTIFICIAL NEURAL NETWORK REVEALS NEW PUTATIVE BINDING CONFORMATIONS. Stefano Motta , Alessandro Pandini, Arianna Fornili, Laura Bonati 1450-Pos Board B518 STRUCTURE AND HYDRATION PROPERTY OF LOWMOLECULAR WEIGHT HYALURONIC ACID BY MOLECULAR DYNAMICS SIMULATIONS. Panyakorn Taweechat, Ras Pandey, Pornthep Sompornpisut 1451-Pos Board B519 SMALL MOLECULE INTERACTIONS WITH BACTERIAL CELL MEMBRANES: ASSESSING INSERTION BARRIERS FOR ALL THE MEMBRANES USING FREE ENERGY COMPUTATIONS. Pradyumn Sharma 1452-Pos Board B520 UNDERSTANDING MOLECULAR MECHANISMS OF THE CRISPR-CAS12A SYSTEM USING MOLECULAR DYNAMICS SIMULATIONS. Chun Chan , Xiaolin Cheng 1453-Pos Board B521 SECONDARY-STRUCTURE CHANGES IMPACT LARP1/MRNA BINDING: SIMULATIONS AND EXPERIMENTS SUGGEST NEW AVENUES FOR ANTI- CANCER DRUG DISCOVERY. Kevin C. Cassidy, Jesse C. Kaminsky, Andrea J. Berman, Jacob D. Durrant 1454-Pos Board B522 CHARACTERIZING WRITHED GEOMETRIES IN OPEN AND CLOSED SUPER- COILED DNA STRUCTURES. Zachary Sierzega , Christopher Prior, Jeffery M. Wereszczynski 1455-Pos Board B523 RATIONALIZING THE EFFECT OF MUTATIONS ON THE EDITING EFFICIENCY OF ADENINE BASE EDITORS. Kartik Lakshmi Rallapalli , Francesco Paesani, Alexis Komor 1456-Pos Board B524 MOLECULAR DETERMINANTS OF GAP JUNCTION CHANNELS CONDUC- TANCE. Claudia Pareja-Barrueto , Maximiliano Rojas, Juan Carlos Sáez, Danilo Gonzalez-Nilo

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