Biophysical Society 2020 Annual Meeting

Protein Structure and Conformation III (Boards B1 - B28) 1731-Pos Board B1 TWO PKA RIA HOLOENZYME STRUCTURAL STATES DEFINE ATP AS AN ISOFORM SPECIFIC ORTHOSTERIC INHIBITOR THAT COMPETES WITH AL- LOSTERIC ACTIVATOR, ATP. Tsan-Wen Lu , Susan S. Taylor 1732-Pos Board B2 THE EFFECT OF SALT AND TEMPERATURE ON THE CONFORMATIONAL CHANGES OF P1LEA-22, A REPEAT UNIT OF PLANTLATE EMBRYOGENESIS ABUNDANT PROTEINS. David Leon, Michael Vermeuel, Priya Gupta, Ryan Aschoff , Michelle R. Bunagan 1733-Pos Board B3 STRUCTURAL AND DYNAMIC EFFECTS OF PHOSPHORYLATION OF PRO- TEIN KINASE A CATALYTIC SUBUNIT. Lily Vu , Susan S. Taylor, Phillip C. Aoto, Jui-Hung Weng 1734-Pos Board B4 RESIDUAL STRUCTURE OF INTRINSICALLY DISORDERED TRANSACTIVA- TION DOMAINS REGULATES THEIR BINDING MECHANISMS TO THE TAZ1 DOMAIN OF CBP. Yifan Zeng , Meng Gao, Yongqi Huang 1735-Pos Board B5 HIGHER-ORDER CLUSTERING OF THE TRANSMEMBRANE ANCHOR OF DR5 DRIVES SIGNALING. Tianmin Fu , Hao Wu, James Chou 1736-Pos Board B6 EXPLORING THE STATE OF THE F 1 -ATPASE AFTER ATP BINDING AND BEFORE ADP RELEASE: EFFECTS OF CONFORMATIONAL CHANGES ON PHOSPHATE DISPLACEMENT. Ricardo A. Matute , Sandor Volkan-Kacso, Rudolph A. Marcus 1737-Pos Board B7 STUDYING PROLYL OLIGOPEPTIDASE CONFORMATIONAL CHANGES WITH FLUORESCENT PYRENE PROBES. Gabriel S. Santos, William Y. Oyadomari, Elizangela A. Carvalho, Marcelo F. Marcondes, Vitor Oliveira 1738-Pos Board B8 PROBING RELATIVE DOMAIN MOBILITY OF CLASS-I MAJOR HISTOCOM- PABILITY COMPLEX MOLECULES THROUGH RESIDUAL DIPOLAR COU- PLINGS. Hau V. Truong , Nikolaos Sgourakis 1739-Pos Board B9 ROLE OF WATER MOLECULES IN THE WAVELENGTH REGULATION OF PHOTO SWITCHABLE RHODOPSIN MIMIC (HCRBPII). Nona Ehyaei , Zahra Nossoni, Hadi Nayebi Gavgani, Meisam Nosrati, Wenjing Wang, Joelle Eaves, Mustapha Akhdar, Chrysoula Vasileilou, Babak Borhan, James H. Geiger 1740-Pos Board B10 FLUORESCENT ANALOGUE OF HEXA-COORDINATE GLOBINS TO MONITOR ACCESSIBILITY OF THE HEME POCKET. Maria J. Santiago Estevez , Ruipeng Lei, Valerie Derrien, Sophie Bernad, Jaroslava Miksovska 1741-Pos Board B11 DESIGN OF INHIBITORY PEPTIDES TARGETING A CRYPTIC POCKET IN TEM- 1 BETA-LACTAMASE. Neha Vithani , Gregory R. Bowman 1742-Pos Board B12 Travel Awardee INHIBITING CALPAIN DEPENDENT DEGRADATION OF DESMOPLAKIN.  Kendahl Ott , Taylor Albertelli, Meagen Ackermann, Heather Manring, Nathan T. Wright 1743-Pos Board B13 THE MOLECULAR MECHANISM OF CA 2+ TRIGGERED DREAM DIMERIZA- TION. Maria D Santiago , Jaroslava Miksovska

1744-Pos Board B14 DIRECTLY DETECTION OF A SINGLE AMINO ACID MOLECULE WITH AN AEROLYSIN NANOPORE. Bo Yuan, Xueyuan Wu, Shuang Li, Yilun Ying , Yi-Tao Long 1745-Pos Board B15 STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF EPPA. Chelsie L. Greene 1746-Pos Board B16 INTERMEDIATE CONFORMATIONS BETWEEN THE NON-FUSOGENIC AND FUSOGENIC CONFORMATIONS OF THE LOOP 36 OF HEMAGGLUTI- NIN. Cristina E. Ramirez , Klever D. Cajamarca, Marco V. Bayas 1747-Pos Board B17 VALIDATION OF HYDROGEN EXCHANGE MASS SPECTROSCOPY (HXMS) NATIVE-STATE PROTEIN STABILITY METHOD.  Jasper Flint , Isabella Han 1748-Pos Board B18 CIRCULAR DICHROISM STUDY OF LATE EMBRYOGENESIS ABUNDANT PEP- TIDES IN REVERSE MICELLES. Michelle R. Bunagan , Kyle Barrie, Melvin Paulose, Stephen Schmidt, Christopher Ratanski 1749-Pos Board B19 A UNIFIED WORKFLOW TO IDENTIFY QUATERNARY STRUCTURES AND CHANGES IN PROTEIN-PROTEIN INTERACTIONS FROM CROSSLINKING- BASED MASS SPECTROMETRY. Catherine Barnier , Lolita Piersimoni, Janet Price, Manolo Plasencia, Matthew R. Chapman, Phillip C. Andrews, Peter L. Freddolino 1750-Pos Board B20 UNFOLDING NATURE’S ORIGAMI ACETONITRILE’S ROLE AS A PROTEIN DENATURANT. Amritha Anup , Jesmyda Viyano 1751-Pos Board B21 UNDERLYING MECHANISM FOR STIMULATED GMP FORMATION IN A UNIQUE LARGE GTPASE HGBP1. Sowmiya Gupta , Nikunj H. Raninga, Apurba K. Sau 1752-Pos Board B22 INFRARED STUDIES OF AB PEPTIDES WITH COPPER AND ZINC: LINKING INTERACTIONS WITH STRUCTURAL CHANGES. Tewaldemedhine Gebrejesus , Keyon Carter, Gina M. MacDonald 1753-Pos Board B23 A HOST-GUEST SYSTEM FOR UNDERSTANDING PROTEIN-NANOPARTICLE INTERACTIONS. Md Siddik Alom , Sharkeisha Jackson, Yasiru R. Perera, Rahul Yadav, Nicholas C. Fitzkee 1754-Pos Board B24 IONIC LIQUIDS INDUCE STRUCTURAL CHANGES OF BSA AND HSA IN AQUEOUS MEDIA.  Juliana Raw , Leandro R. Barbosa 1755-Pos Board B25 Travel Awardee PLASMA INDUCED MODIFICATION OF BIOMOLECULES (PLIMB) FOR EPIT- OPE MAPPING. Daniel Benjamin , Faraz A. Choudhury, Benjamin Minkoff, Claire Bramwell, St John Skilton, J. Leon Shohet, Michael R. Sussman 1756-Pos Board B26 PROGRAMMABLE DISASSEMBLY OF PROTEIN CAGES BY SELECTIVE PRO- TEOLYSIS.  Justin E. Miller , Yashes Srinivasan, Todd O. Yeates 1757-Pos Board B27 Travel Awardee CHARACTERIZATION OF THE THERMAL AND CHEMICAL DENATURATION OF THE MATRIX PROTEIN FROM HRSV. Giovana Cavenaghi Guimarães , Vi- tor BrassolattiMachado, Jéssica Maróstica de Sá, Marcelo Andres Fossey, Ícaro Putinhon Caruso, Fatima Pereira de Souza

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