Biophysical Society 2020 Annual Meeting

Wednesday, February 19 New Council Meeting 8:00 am - 11:00 am, Room 32A Poster Viewing 8:00 am - 3:00 pm, Exhibit Hall Symposium Membrane Proteins in Infectious Disease 8:15 am - 10:15 am, Ballroom 20A Chair Francesca Marassi, Sanford Burnham Prebys Medical Discovery Institute 2349-Symp 8:15 am ASSEMBLY AND BUDDING OF FILOVIRUSES FROM THE HOST CELL PLASMA MEMBRANE.  Robert V. Stahelin 2350-Symp 8:45 am SMALL MOLECULE INHIBITION OF MEMBRANE FUSION MEDIATED BY THE FLAVIVIRUS ENVELOPE PROTEIN.  Priscilla L. Yang No Abstract 9:15 am CONFORMATIONAL STATES OF THE HIV-1 ENVELOPE GLYCOPROTEIN OBSERVED BY SMFRET. Walther Mothes 2351-Symp 9:45 am MOLECULAR BASIS FOR PATHOGEN-HOST INTERACTIONS.  Francesca M. Marassi Symposium Shapeshifting: Proteins with More Than One Structure 8:15 am - 10:15 am, Ballroom 20D Chair Sarah Bondos, Texas A&M University 2352-Symp 8:15 am IDENTIFICATION AND PREDICTION OF FOLD-SWITCHING PROTEINS.  Loren Looger, Ananya K. Majumdar, Lauren Porter 2353-Symp 8:45 am EVOLUTION OF A METAMORPHIC PROTEIN.  Brian F. Volkman 2354-Symp 9:15 am PROTEIN FOLDING AND CONFORMATIONAL FRUSTRATION.  Shachi Gosavi 2355-Symp 9:45 am SHAPE-SHIFTING TO REGULATE AND DIVERSIFY TRANSCRIPTION FACTOR FUNCTION.  Sarah Bondos , Kelly Churion, Rebecca Booth, Sydney Tippelt Platform Protein Structure, Prediction, and Design 8:15 am - 10:15 am, Ballroom 20BC Co-Chairs Caitlin Davis, Yale University Christopher Prior, Durham University, United Kingdom 2356-Plat 8:15 am CHARACTERIZATION OF A PH-DEPENDENT CARGO-DELIVERY PROTEIN CHIMERA.  Suzanne I. Sandin , Christopher Randolph, Eva de Alba

2357-Plat 8:30 am DESIGN AND CONSTRUCTION OF AN AEROLYSIN SINGLE-MOLECULE INTERFACE FOR SINGLE-MOLECULE SENSING.  Xue-yuan Wu , Meng-Yin Li, Yi-Lun Ying, Yi-Tao Long 2358-Plat 8:45 am AB INITIO TERTIARY STRUCTURE PREDICTION FROM SMALL ANGLE SCAT- TERING DATA.  Christopher Prior , Ehmke Pohl, Owen Davies 2359-Plat 9:00 am DE NOVO PROTEIN STRUCTURE MODELING TOOL MAINMAST ENHANCED FOR MULTIPLE CHAIN COMPLEXES AND BOUND LIGANDS.  Genki Terashi , Daisuke Kihara 2360-Plat 9:15 am FRET-ASSISTED PROTEIN STRUCTURE POSTDICTION OF CASP13 TARGETS.  Mykola Dimura , Holger Gohlke, Claus A. Seidel 2361-Plat 9:30 am COMBINING PHYSICS-BASED AND EVOLUTION-BASED METHODS TO DESIGN ANTIBODIES AGAINST AN EVOLVING VIRUS.  Eric Jakobsson, Amir Barati Farimani , Emad Tajkhorshid, Narayana Aluru 2362-Plat 9:45 am TOWARDS THE DE NOVO DESIGN OF FUNCTIONAL METALLOPROTEINS.  Ketaki Belsare , Nicholas Polizzi, Lior Shtayer, William DeGrado 2363-Plat 10:00 am QUINARY STRUCTURE MODULATES CONSENSUS PROTEIN SEQUENCE STABILITY IN CELLS.  Caitlin Davis , Martin Gruebele Platform Other Channels 8:15 am - 10:15 am, Room 23ABC Co-Chairs FUNCTIONAL ANALYSIS OF THE ISOLATED VOLTAGE SENSOR DOMAIN PRESENT IN THE MAMMALIAN SPERM-SPECIFIC NA + /H + EXCHANGER BY PATCH-CLAMP CURRENT RECORDING.  César Arcos Hernández , Esteban Suarez, Leon Islas, Takuya Nishigaki 2365-Plat 8:30 am A MODULAR TOOLBOX FOR OPTOGENETIC MANIPULATION OF K + CONDUCTANCE.  Gerhard Thiel , Anja J. Engel, Kerri Kukovetz, Kerri Kuk- ovetz, Matea Cortolano, Sebastian Höler, Monica Beltrame, Anna Moroni 2366-Plat 8:45 am MOLECULAR MECHANISMS UNDERLYING OXIDATION SENSITIVITY OF VRAC.  Sara Bertelli , Michael Pusch 2367-Plat 9:00 am CONNEXIN 31 MUTATIONS ASSOCIATED WITH SKIN DISEASE AND DEAF- NESS DISPLAY A VARIETY OF PHENOTYPES WHEN EXPRESSED IN XENO- PUS OOCYTES.  Samuel Sunners , Anhthi Tanguyen, Adedoyin Akingbade, Ingrid M. Skerrett 2368-Plat 9:15 am REPURPOSING INTRACELLULAR FLUORESCENT BIOSENSORS TO VISUAL- IZE EXTRACELLULAR FLUXES.  Daniel A. Gutierrez 2369-Plat 9:30 am ROLES OF HYDROGEN-BONDING NETWORKS IN PROTON CHANNEL FUNCTION AS REVEALED THROUGH DE NOVO DESIGNED PROTON CHAN- NELS.  Huong T. Kratochvil , John M. Nicoludis, William F. DeGrado Michael Pusch, Istituto di Biofisica, CNR, Italy Ingrid Skerrett, SUNY Buffalo State College 2364-Plat 8:15 am

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