Biophysical Society 2020 Annual Meeting

2536-Pos Board B82 A COMPUTATIONAL MODEL FOR UNDERSTANDING THE OLIGOMERIZA- TION MECHANISMS OF TNF RECEPTOR SUPERFAMILY. Zhaoqian Su , Yinghao Wu 2537-Pos Board B83 MICROSCOPIC CHARACTERIZATION OF HEPATITIS B VIRUS CAPSID DIS- ASSEMBLY. Zhaleh Ghaemi , Martin Gruebele, Emad Tajkhorshid Protein Dynamics and Allostery III (Boards B84 - B106) 2538-Pos Board B84 ALLOSTERIC REGULATION OF GLUTAMATE DEHYDROGENASE DEAMINA- TION ACTIVITY. Soumen Bera 2539-Pos Board B85 A CONSERVED LOCAL STRUCTURAL MOTIF CONTROLS THE KINETICS OF PTP1B CATALYSIS. Christine Y. Yeh , Jesus Izaguirre, Jack Greisman, Lindsay Willmore, Paul Maragakis, David E. Shaw 2540-Pos Board B86 SOLUTION NMR INVESTIGATION OF HIV-1 REPLICATION CYCLE. Bhargavi Ramaraju, Lalit Deshmukh 2541-Pos Board B87 ROLE OF PROTEIN DYNAMICS IN THE FUNCTION OF P38 KINASE AND PROTEIN TYROSINE PHOSPHATASE 1B. Senthil Kumar Ganesan , Michael W. Clarkson, Kristiane Torgeson Pelletier, Rebecca Page, Wolfgang Peti 2542-Pos Board B88 PARTIAL DISSOCIATION OF ANTIGENIC PEPTIDES FROMMHC I OR HOW TO DEAL WITH CONFLICTING RESULTS FROM DIFFERENT ENHANCED SAMPLING METHODS? Sebastian Wingbermühle , Lars V. Schäfer 2543-Pos Board B89 A SIX-STATE BINDING MODEL GIVES RISE TO DYNAMIC ACTIVITY AND ENERGY LANDSCAPES IN YEAST CHORISMATE MUTASE.  Scott D. Gorman , Dennis S. Winston, Debashish Sahu, David D. Boehr 2544-Pos Board B90 REGULATION OF THE ACTIVITY OF BACTERIAL TYROSINE KINASES.  Fatlum Hajredini , Andrea Piserchio, Rinat Abzalimov, Ranajeet Ghose 2545-Pos Board B91 UNVEILING THE PH-DEPENDENT DYNAMICS OF THE PREPORE-TO-PORE TRANSITION OF A TC TOXIN. Svetlana Kucher , Daniel Roderer, Tufa E. Assafa, Stefan Raunser, Enrica Bordignon 2546-Pos Board B92 THE ROLE OF BACKBONE AND SIDECHAIN DYNAMICS ON FIMH ALLO- STERY.  Jenny Liu , Kerim Dansuk, Sinan Keten, Luis Amaral 2547-Pos Board B93 Travel Awardee AB-INITIO PREDICTION OF NMR SPIN-RELAXATION PARAMETERS FROM MD SIMULATIONS. Po-Chia Chen , Maggy Hologne, Olivier Walker, Janosch Hennig 2548-Pos Board B94 SILVER IONS CAUSED FASTER DIFFUSION OF H-NS PROTEINS IN LIVE E. COLI BY WEAKENING THE BINDING BETWEEN H-NS PROTEINS AND DNA. Asmaa A. Sadoon , Prabhat Khadka, Jack freeland, Ravi Gundam- pati, Rayan Mason, Mazon Ruiz, Suresh K. Thallapuranam, Jing Chen, Yong Wang 2549-Pos Board B95 STUDY OF SELF-ASSOCIATION OF HUMAN CSTF-64 RNA RECOGNITION MOTIF. Elahe Masoumzadeh , Michael Latham, Clinton MacDonald, Petar Grozdanov

2550-Pos Board B96 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE EXON 19 DELETION MUTATIONS DISPLAY VARIABILITY IN ACTIVATION AND DRUG RESPON- SIVENESS. Benjamin P. Brown 2551-Pos Board B97 THE STAPHYLOCOCCUS AUREUS ISDH RECEPTOR FORMS A DYNAMIC COMPLEX WITH HUMAN HEMOGLOBIN AND TRIGGERS HEME RELEASE VIA TWO DISTINCT HOT SPOTS.  Joseph A. Clayton , Jeffery M. Wereszc- zynski 2552-Pos Board B98 WHAT TIME IS IT? RECONSTITUTING A CYANOBACTERIA CLOCK TO TIME THE GENE EXPRESSION IN VITRO. Archana G. Chavan , Joel Heisler, Yong- gang Chang, Andy LiWang 2553-Pos Board B99 IS THE PROTEIN DYNAMICAL TRANSITION USEFUL? Akansha Sharma , Deepu K. George, Kimberly Crossen, Jeffrey McKinney, Cheryl Kerfeld, Andrea Markelz 2554-Pos Board B100 PERIODIC TABLE OF F-TYPE ATPASES.  John W. Vant , Abhishek Singharoy 2555-Pos Board B101 RECEPTORS’ MOSAICS AND ALLOSTERY FOR PHARMACOLOGY. Zeineb Si Chaib, Alessandro Marchetto, Klevia Dishnica, Paolo Carloni, Alejandro Giorgetti, Giulia Rossetti 2556-Pos Board B102 DYNAMIC DISEASE LANDSCAPE OF A CANCER DRIVING FUSION KI- NASE. Phillip C. Aoto , Susan S. Taylor 2557-Pos Board B103 Travel Awardee MECHANISM OF ALLOSTERIC INHIBITION OF PLASMODIUM FALCI- PARUM CGMP-DEPENDENT PROTEIN KINASE. Olivia Byun , Katherine Van, Philipp Henning, Friedrich W. Herberg, Giuseppe Melacini 2558-Pos Board B104 STRUCTURAL BASIS FOR THE ROBUST SUBSTRATE PHOSPHORYLATION BY MAPK P38Α UNDER THE STRESS-ASSOCIATED ATP-DECREASED, WEAKLY ACIDIC PH CONDITION ELUCIDATED BY SOLUTION NMR. Yuji Tokunaga , Koh Takeuchi, Hideo Takahashi, Ichio Shimada 2559-Pos Board B105 ALLOSTERY AND CONFORMATIONAL DYNAMICS IN TYROSINE KINASE REGULATION. WilliamMarsiglia, Joseph Katigbak, Sijin Zheng, Moosa Mohammadi, Yingkai Zhang, Nate Traaseth 2560-Pos Board B106 SOLVENT MAPPING APPROACH FOR UNCOVERING CRYPTIC POCKETS IN MEMBRANE-BOUND PROTEINS. Lorena Zuzic , Jan K. Marzinek, Jim Warwicker, Peter J. Bond Membrane Protein Structures II (Boards B107 - B124) 2561-Pos Board B107 PROTEIN-LIPID INTERACTIONS IN FORMATION OF VIRAL ENVE- LOPES. Natalia V. Kuzmina, Anna S. Loshkareva, Liudmila A. Shilova, Eleonora V. Shtykova, Denis G. Knyazev, Joshua Zimmerberg, Oleg V. Batishchev 2562-Pos Board B108 PHASE PLATE CRYO-EM STRUCTURE OF FORMYLPEPTIDE RECEPTOR 2 BOUND TO AN INHIBITORY G PROTEIN. Gongpu Zhao , Xing Meng 2563-Pos Board B109 INFLUENCE OF THE LIPID-PROTEIN INTERFACE ON MSCS MECHANOSEN- SITIVE CHANNEL GATING AT HIGH RESOLUTIONS. Bharat Reddy , Navid Bavi, Eduardo Perozo

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