Biophysical Society 2020 Annual Meeting

Calcium Signaling II (Boards B298 - B313)

2764-Pos Board B310 CYTOKINESIS TRIGGERS TWO SEPARATE SPIKES OF INTRACELLULAR CALCIUM. Qian Chen 2765-Pos Board B311 A POWERFUL TRANSFECTION REAGENT FOR BUILDING STABLE GPCR EXPRESSING CELL LINES. Shu Kan , Jinfang Liao, Zhenjun Diwu 2766-Pos Board B312 CATERPILLAR ORAL SECRETION ELICITS REACTIVE OXYGEN SPECIES IN ISOLATED PLANT PROTOPLASTS. Akanksha Gandhi , Cruz Chapa, Rupesh Kariyat, Nirakar Sahoo 2767-Pos Board B313 CALCIUM BUFFERING BY FLUORESCENT INDICATORS - IMPLICATIONS AND EASY SOLUTIONS. Krzysztof Hyrc , Ziemowit Rzeszotnik, Mark P. Goldberg, Colin G. Nichols Intracellular Calcium Channels and Calcium Sparks and Waves II (Boards B314 - B330) 2768-Pos Board B314 DEFECTIVE INTERACTION OF CAMWITH RYR2 CAM-BINDING POCKET MIGHT CONTRIBUTE TO ARRHYTHMOGENIC CARDIAC DISEASE. Michail Nomikos , Angelos Thanassoulas, Vyronia Vassilakopoulou, Brian L. Calver, Evangelia Livaniou, Bared Safieh-Garabedian, Egon Toft, George Nounesis, F. Anthony Lai 2769-Pos Board B315 RYR2 HYPERACTIVITY GENERATES VENTRICULAR TACHYCARDIA SUS- CEPTIBILITY IN STRUCTURAL HEART DISEASE. Kyungsoo Kim , Bjorn C. Knollmann 2770-Pos Board B316 RECRUITING RYRS TO OPEN IN A CA 2+ RELEASE UNIT. Dirk Gillespie 2771-Pos Board B317 SLOW-RAPID-SLOW PACING IN THE HEART HAVING CASQ2 G112+5X GENE MUTATION PRODUCES EADS AS THE MECHANISM OF CPVT DURING ADRENERGIC STIMULATION. Roshan Paudel , Aman Ullah, Mohsin S. Jafri 2772-Pos Board B318 INHIBITION OF TYROSINE KINASE PYK2 IN HYPERTROPHIC HEARTS: CEL- LULAR MECHANISMS OF ANTI-ARRHYTHMIC EFFECTS. Radmila Terentieva , Shanna Hamilton, Tae Yun Kim, Iulia Polina, Peter Bronk, Karim Roder, Jin O-Uchi, Gideon Koren, Sandor Gyorke, Andriy E. Belevych, Bum-Rak Choi, Dmitry A. Terentyev 2773-Pos Board B319 PROTOCOL DEVELOPMENT FOR EXPRESSING FUNCTIONAL RYANODINE RECEPTORS IN HEK293-6E SUSPENSION CELLS. Michael Wold , Robyn T. Rebbeck, Elisa Bovo, Aleksey V. Zima, David D. Thomas, Razvan L. Cornea 2774-Pos Board B320 Travel Awardee LUMINAL CALCIUM CONTROL OF TYPE-1 INOSITOL 1,4,5-TRISPHOS- PHATE RECEPTOR. Allison M. Tambeaux, Yuriana Aguilar-Sanchez , Rafael Mejia-Alvarez, Michael Fill, S.R. Wayne Chen, Josefina Ramos-Franco 2775-Pos Board B321 CORRELATING CALCIUM SPARKS AND RYANODINE RECEPTOR LOCALIZA- TION IN LIVE CARDIOMYOCYTES. Yufeng Hou, Martin Laasmaa , Jia Li, Or- nella Manfra, Xin Shen, Peter P. Jones, Christian Soeller, William E. Louch 2776-Pos Board B322 REGULATION OF HUMAN RYR2 BY CALMODULIN. Roman Nikolaienko , Elisa Bovo, Christopher Hoover, Robyn Rebbeck, David D. Thomas, Raz- van L. Cornea, Aleksey V. Zima

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2752-Pos Board B298 TO FACE OR NOT TO FACE: RELATIONSHIP OF IP3 RECEPTORS AND MITO- CHONDRIA IN PURKINJE FIBERS OF CEREBELLUM. Clara Franzini-Armstrong , V. Ramesh Iyer 2753-Pos Board B299 COMPUTATIONAL MODELING OF LPS- AND ATP-MEDIATED CYTOKINE PRODUCTION IN MACROPHAGES. Byeongjae Chun , Peter M. Kekenes- Huskey, Chris Richards 2754-Pos Board B300 MULTIPLE FEEDBACK MECHANISMS UNDERLYING BETA CELL SECRETORY OSCILLATIONS. Benjamin M. Thompson , Isabella Marinelli, Richard Bertram, Arthur Sherman, Leslie S. Satin 2755-Pos Board B301 CARDIAC CAMKIIΔ MEMORY: POST-TRANSLATIONAL MODIFICATION- MEDIATED PROLONGATION OF CAMKIIΔ IN AUTONOMOUSLY ACTIVE OPEN STATE. Christopher Y. Ko , Leann T. Le, Mitchell R. Simon, Razvan L. Cornea, Julie Bossuyt, Donald M. Bers 2756-Pos Board B302 MATHEMATICAL MODELING OF CALCIUM BINDING TO HUMAN, PLANT, AND ENGINEERED CALMODULIN, AS WELL AS CARDIAC AND SLOW SKELETAL TROPONIN. Garrett T. Hauck , Yongjun Kou, Svetlana Tikunova, Jonathan P. Davis 2757-Pos Board B303 CALCIUM STORE-OPERATED CURRENTS IN HUMAN SKIN CELLS. Declan Manning , Richard L. Evans, Caroline Dart 2758-Pos Board B304 MUSCARINIC RECEPTOR STIMULATION DIFFERENTIALLY REGULATES NUCLEOPLASMIC CALCIUM IN ATRIAL AND VENTRICULAR MYOCYTES.  Andriy E. Belevych , Jiaoni Li, Andrei Stepanov, Ingrid M. Bonilla, Dmitry A. Terentyev, Sandor Gyorke 2759-Pos Board B305 ZINC PROTECTION OF FERTILIZED EGGS IS CONSERVED IN NON-MAM- MALIAN SPECIES. Rachel E. Bainbridge , Katherine Wozniak, Wesley A. Phelps, Steven M. Sanders, Matthew L. Nicotra, Miler T. Lee, Anne E. Carlson 2760-Pos Board B306 LOW RYR2 SENSITIVITY TO FLECAINIDE COMBINED WITH SLOW SARCO- LEMMAL ENTRY AND RAPID MITOCHONDRIAL ACCUMULATION MAY EXPLAIN THE ABSENCE OF RYR2 EFFECTS INTACT WILD TYPE MYO- CYTES. Emma J. Steer, Zhaokang Yang, Derek S. Steele 2761-Pos Board B307 ANO1, CA V 1.2 AND IP 3 R FORM A FUNCTIONAL UNIT OF EXCITATION- CONTRACTION COUPLING DURING AGONIST-MEDIATED CONTRACTION OF MOUSE PULMONARY ARTERIAL SMOOTH MUSCLE. Joydeep Aoun, Katie Mayne, Julius Baeck, Kenton M. Sanders, Sean M. Ward, Iain A. Greenwood, Simon A. Bulley, Jonathan H. Jaggar, Scott Earley, Normand Leblanc 2762-Pos Board B308 HETERO-OLIGOMERIZATION OF THE MICROPEPTIDE REGULINS THAT MODULATE CALCIUM TRANSPORT ACTIVITY. Garrett T. Hauck, Sean R. Cleary, Seth L. Robia 2763-Pos Board B309 DATA DRIVEN MODELING OF ALZHEIMER’S DISEASE ASSOCIATED BETA AMYLOID PORES HINTS TOWARDS PROGRESSIVE CA 2+ -INDUCED CELL TOXICITY. Syed Islamuddin Shah , Ian Parker, Angelo Demuro, Ghanim Ullah

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