Biophysical Society 2020 Annual Meeting

2802-Pos Board B348 LYSOZYME-LIKE MODEL PROTEIN DIFFUSION AND ADSORPTION ON A CHARGED SURFACE. EFFECTS OF HYDRODYNAMIC INTERACTIONS. Paweł Czajka, Maciej J. Dlugosz 2803-Pos Board B349 DASHING THROUGH THE MAZE: ACTIVE MIXING IN THE ENDOPLASMIC RETICULUM. Katherine M. Xiang, Edward Avezov, Elena F. Koslover 2804-Pos Board B350 EXPORT/IMPORT OF EXOSOMAL CIRS-7: A SINGLE MOLECULE ANALYSIS OF CIRCULAR RNA TRAFFICKING. Andreas Schmidt , Ameya P. Jalihal, Guoming Gao, Nils G. Walter 2805-Pos Board B351 KINETIC PROOFREADING USING SUBSTRATE GRADIENTS AND ENZYME DIFFUSION. Vahe Galstyan , Kabir Husain, Fangzhou Xiao, Arvind Muru- gan, Rob Phillips 2806-Pos Board B352 CHARACTERIZATION OF MEMBRANE CONTACT SITES FOR THE FACILITA- TION OF LIPID EXCHANGE AT THE MALARIA PARASITE - RED BLOOD CELL INTERFACE. Matthias Garten , Josh Beck, Robyn Roth, John E. Heuser, Tatyana Tenkova-Heuser, Christopher K.E. Bleck, Daniel E. Goldberg, Joshua Zimmerberg 2807-Pos Board B353 INTRACELLULAR TRANSPORT DYNAMICS OF UPCONVERTING NANOPAR- TICLES IN LIVING CELLS. Kyujin Shin , Sanggeun Song, Yo Han Song, Seungsoo Hahn, Ji-Hyun Kim, In-Chun Jeong, Jaeyoung Sung, Kang Taek Lee Voltage-gated Na Channels (Boards B354 - B378) 2808-Pos Board B354 THE MECHANISM OF ION CONDUCTION AND SELECTIVITY IN THE EU- KARYOTIC NA V PAS CHANNEL. Juan Nogueira, Ben Corry 2809-Pos Board B355 RELATIVE VOLTAGE SENSOR ACTIVATION KINETICS DETERMINES THE EF- FECTS OF SENSOR NEUTRALIZATION IN VOLTAGE-GATED SODIUM CHAN- NELS. Niklas Brake , Adamo Mancino, Yuhao Yan, Takushi Shimomura, Yoshihiro Kubo, Derek Bowie, Anmar Khadra 2810-Pos Board B356 EXPLORING NONCANONICAL COUPLING IN VOLTAGE-GATED SODIUM CHANNELS. Fraol Galan , Carlos Alberto Bassetto Jr, Benjamin Fosque, Francisco Bezanilla 2811-Pos Board B357 MULTISCALE MOLECULAR DYNAMICS TO EXPLORE VOLTAGE-GATED SODIUM CHANNEL OLIGOMERISATION. William Glass, Anna L. Duncan, Jessica Mitchell, Philip C. Biggin 2812-Pos Board B358 CYSTEINE MUTAGENESIS TO PROBE SITE-SPECIFIC INTERACTIONS IN THE VOLTAGE SENSOR MODULE OF HNAV1.4.  James R. Groome , Ryann Camp, Landon Bayless-Edwards 2813-Pos Board B359 REVISITING NA V CHANNEL INACTIVATION: THE ROLE OF FIBROBLAST GROWTH FACTOR HOMOLOGOUS FACTOR (FHF). Paweorn Angsutararux , Taylor L. Voelker, Catherine Malcolm, Wandi Zhu, Jona- than R. Silva

2814-Pos Board B360 MYOTONIC MUTATIONS OF NAV1.4 LOCATED AT EF HAND-LIKE MOTIF IN C-TERMINUS IMPAIR FAST INACTIVATION. Riho Horie , Tomoya Kubota, Jinsoo Koh, Rieko Tanaka, Yuichiro Nakamura, Sasaki Ryogen, Hidefumi Ito, Masanori P. Takahashi 2815-Pos Board B361 CRYSTAL STRUCTURES OF CALCIUM-LOADED CALMODULIN IN COMPLEX WITH C-TERMINAL DOMAINS OF VOLTAGE-GATED SODIUM CHAN- NELS. Filip Van Petegem , Ching-Chieh Tung, Bernd Gardill, Ricardo E. Rivera-Acevedo 2816-Pos Board B362 A CALMODULIN MUTATION THAT DYSREGULATES NA V 1.6 BUT NOT NA V 1.5. Yusuf Olgar , Sandor Gyorke, Rengasayee Veeraraghavan, Jona- than P. Davis, Przemyslaw Radwanski 2817-Pos Board B363 RILUZOLE AS A PROTOTYPE OF A NEW CLASS OF SODIUM CHANNEL INHIBITORS. Mátyás Csaba Földi , Péter Lukács, Krisztina Pesti, Andras Malnasi-Csizmadia, Arpad Mike 2818-Pos Board B364 HOW FAST IS RILUZOLE. Krisztina Pesti , Péter Lukács, Arpad Mike 2819-Pos Board B365 WHAT MAKES A COMPOUND A SODIUM CHANNEL INHIBITOR. Adam Toth , Peter Lukacs, Arpad Mike 2820-Pos Board B366 ABERRANT CALMODULIN REGULATION OF NAV1.5 CHANNELS LINKED TO INHERITED CARDIAC ARRHYTHMIA. Nourdine Chakouri , Po wei Kang, Johanna Diaz, Gordon F. Tomaselli, Manu B. Johny 2821-Pos Board B367 IDENTIFICATION OF A NEW GAIN-OF-FUNCTION MUTATION OF NAV1.5 ASSOCIATED WITH ATRIAL FIBRILLATION IN AN AFRICAN-AMERICAN FAMILY. Liang Hong , Faisal A. Darbar, Meihong Zhang, Dawood Darbar 2822-Pos Board B368 REDUCED SODIUM CURRENTS AND INCREASED SENSITIVITY TO FLECAINIDE IN ATRIAL CARDIOMYOCYTES, COMPARED TO VENTRICU- LAR. Sian-Marie O’Brien, Andrew P. Holmes, Daniel M. Johnson, Mad- dalena Tessari, Giuseppe Faggian, Larissa Fabritz, Paulus Kirchhof, Davor Pavlovic 2823-Pos Board B369 AN SCN5A SPLICE VARIANT ASSOCIATED WITH HEART FAILURE LEADS TO A REDUCTION IN SODIUM CURRENT THROUGH COUPLED GATING WITH THE WT CHANNEL. Yang Zheng , Haiyan Liu, Xiaoping Wan, Isabelle Deschenes 2824-Pos Board B370 LATE SUSTAINED SODIUM CURRENT (INA,L) IN ADULT HUMAN PRIMARY CARDIOMYOCYTES. Anh Tuan Ton , Andrea Ghetti, Guy Page, Paul E. Miller, Najah Abi Gerges 2825-Pos Board B371 PROTECTIVE EFFECT OF CANNABIDIOL AGAINST OXIDATIVE STRESS AND CYTOTOXICITY EVOKED BY HIGH GLUCOSE IN CARDIAC VOLTAGE-GATED SODIUM CHANNELS. Mohamed A. Fouda , Mohammad-Reza Ghovanloo, Peter C. Ruben 2826-Pos Board B372 ALTERED AXONAL TRAFFICKING OF NAV1.7 IN CULTURED PERIPHERAL NEURONS IN RESPONSE TO INFLAMMATORY MEDIATORS AND PACLI- TAXEL. Elizabeth J. Akin , Grant P. Higerd, Shujun Liu, Fadia B. Dib-Hajj, Stephen G. Waxman, Sulayman D. Dib-Hajj 2827-Pos Board B373 THE SUBCELLULAR LOCALIZATION OF SODIUM CHANNELS & POTASSIUM CHANNELS IN THE NODES OF RANVIER.  Jiemin Lou

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