Biophysical Society 2020 Annual Meeting

2904-Pos Travel Awardee SEX DIFFERENCES IN REGULATING THE CARDIAC TRANSCRIPTOME WITHIN A MURINE MODEL FOR HYPERTROPHIC CARDIOMYOPATHY.  Karissa M. Dieseldorff Jones , Cynthia Vied, Isela C. Valera, Prescott B. Chase, Michelle S. Parvatiyar, J. Renato Pinto 2905-Pos Board B451 A HIGH ALA MUTANT OF THE C-TERMINAL REGION OF HUMAN CARDIAC TNT HAS A LARGE IMPACT ON REGULATION. Dylan Johnson, Li Zhu, Maicon Landim Vieira , J. Renato D. Pinto, Joseph M. Chalovich 2906-Pos Board B452 CONNECTING CARDIAC SARCOLEMMA PROTEIN CONTENT WITH SARCO- MERIC FUNCTION.  Isabella Leite Coscarella , Maicon Landim Vieira, Isela C. Valera, Amanda L. Wacker, Prescott B. Chase, J. Renato Pinto, Michelle S. Parvatiyar 2907-Pos Board B453 THE ROLE OF CMYBP-C IN REGULATING THE FRANK-STARLING RELATION- SHIP. Laurin M. Hanft , Daniel P. Fitzsimons, Timothy A. Hacker, Richard L. Moss, Kerry S. McDonald 2908-Pos Board B454 PHOSPHODIESTERASE 2 AND 3 REGULATE COMPARTMENTALIZED BETA2- ADRENERGIC RECEPTOR CAMP SIGNALING. Michael W. Rudokas , John P. Post, Chase M. Fiore, Shailesh R. Agarwal, Robert D. Harvey 2909-Pos Board B455 Travel Awardee OBSERVING THE MYOSIN SUPER-RELAXED STATE (SRX) IN CARDIAC THICK FILAMENTS. Sami Chu , Sriya Byrapuneni, David D. Thomas, Joseph M. Muretta 2910-Pos Board B456 OSMOTIC COMPRESSION INFLUENCES CROSS-BRIDGE DETACHMENT RATE IN TRANSGENIC HYPERTROPHIC CARDIOMYOPATHY VARIANT HCTNT-I79N AND NON-TRANSGENIC MOUSE CARDIAC MUSCLE. Maicon Landim Vieira , Bjorn C. Knollmann, Hyun S. Hwang, Coen A. Ottenheijm, J. Renato D. Pinto, Prescott B. Chase 2911-Pos Board B457 DESIGN OF AN OPTICAL TWEEZERS SYSTEMWITH FAST DIGITAL FEED- BACK FOR STUDYING THE MECHANOCHEMISTRY OF CARDIAC MYO- SIN. William Stump , Thomas Blackwell, Sarah R. Clippinger, Michael J. Greenberg 2912-Pos Board B458 CHARACTERIZATION OF THE CARDIAC MYOSIN INHIBITOR CK-3773274: A POTENTIAL THERAPEUTIC APPROACH FOR HYPERTROPHIC CARDIO- MYOPATHY.  James J. Hartman , Darren T. Hwee, Jingying Wang, Yangsong Wu, Julia Schaletzky, Preeti Paliwal, Ken Lee, Khanha D. Taheri, Eddie Wehri, Todd J. Ewing, Joseph P. Michel, Chihyuan Chuang, Eva R. Chin, Bradley P. Morgan, Fady I. Malik Microtubules, Structure, Dynamics, and Associated Proteins (Boards B459 - B475) 2913-Pos Board B459 TUBULIN TAILS AND THEIR MODIFICATIONS REGULATE PROTEIN DIFFU- SION ON MICROTUBULES. Koby Levy 2914-Pos Board B460 GMPCPP-TUBULIN ISLANDS REGULATE THE MECHANISM AND KINETICS OF MICROTUBULE DEPOLYMERIZATION. George D. Bachand , Jonathan A. Bollinger, Zachary Imam, Mark J. Stevens 2915-Pos Board B461 STUDY OF TAU N-TERMINAL MUTATION, R5L, ON TAU INTERACTION WITH THE MICROTUBULE LATTICE. Alisa Cario , Morgan Dexter, Christo- pher L. Berger Board B450

2916-Pos Board B462 C-TERMINAL TAIL POLYGLYCYLATION AND POLYGLUTAMYLATION ALTER MICROTUBULE MECHANICAL PROPERTIES. Kathryn P. Wall, Harold Hart, Thomas Lee, Cynthia Page, Taviare L. Hawkins, Loren E. Hough 2917-Pos Board B463 ALL TUBULINS ARE NOT ALIKE: HETERODIMER DISSOCIATION DIFFERS AMONG DIFFERENT BIOLOGICAL SOURCES: COMPARISON WITH DIMER ASSOCIATION. Felipe A. Montecinos-Franjola, Sumit K. Chaturvedi, Peter Schuck, Dan L. Sackett 2918-Pos Board B464 SUBNANOMETER MECHANICS OF MICROTUBULE SELF-(DIS)ASSEM- BLY. Maxim Igaev , Helmut Grubmueller 2919-Pos Board B465 Travel Awardee EFFECTS OF SEVERING ENZYMES ON THE LENGTH DISTRIBUTION AND TOTAL MASS OF MICROTUBULES. Yin-wei Kuo , Olivier Trottier, Moham- med Mahamdeh, Jonathon Howard 2920-Pos Board B466 MICROTUBULE POLARITY IN AXONS IS SORTED BY A MOLECULAR GRADI- ENT OF DYNACTIN. Maximilian A. Jakobs , Kristian Franze 2921-Pos Board B467 ULTRAFAST FORCE-CLAMP STUDIES OF THE DIFFUSING MICROTUBULE- BINDING PROTEINS. Ekaterina L. Grishchuk , Vladimir Demidov, Shaowen Wu, Ivan V. Gonchar, Fazly I. Ataullakhanov 2922-Pos Board B468 COMPUTATIONAL ANALYSIS OF NUCLEOTIDE-DEPENDENT MECHANICAL PROPERTIES OF MICROTUBULE PROTOFILAMENTS.  James E. Gonzales , Wonmuk Hwang 2923-Pos Board B469 A REAL-SPACE METHOD TO MEASURE THE PERSISTENCE LENGTH OF DY- NAMIC MICROTUBULES.  Jeffrey Spector , Gilman E.S. Toombes, Kenton Swartz, Antonina Roll-Mecak 2924-Pos Board B470 MICROTUBULE IN VITRO BUNDLE STRUCTURES DEPENDS ON TAU PROJECTION DOMAIN AND IONIC STRENGTH. Hasaeam Cho , Hanjoon Nho, Juncheol Lee, Sang Yeop Lee, Kyeong Sik Jin, Herbert P. Miller, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya, Myung Chul Choi 2925-Pos Board B471 Travel Awardee CAN THRESHOLD CHOICES INFLUENCE OBSERVED MICROTUBULE AGING? Kristopher S. Murray , Ava J. Mauro, Holly V. Goodson 2926-Pos Board B472 MATHEMATICAL MODELING AND SIMULATIONS OF CENTRIOLE POSI- TIONING DURING MITOSIS OF CELLS IN CONFINED ENVIRONMENTS.  Nadia C. Beydoun , Parag Katira, Christian Mercado, Brianna Roseberry 2927-Pos Board B473 BRAIN MICROTUBULE STRUCTURES BEHAVE AS MEMRISTIVE DEVIC- ES. María del Rocío Cantero , Paula L. Perez, Noelia Scarinci, Brenda C. Gutierrez, Horacio F. Cantiello 2928-Pos Board B474 THE DEPENDENCE OF TAU-MEDIATED MICROTUBULE ASSEMBLY AND BUNDLE FORMATION ON GTP AND MG 2+ . Bretton Fletcher , Chaeyeon Song, Phillip A. Kohl, Herbert P. Miller, Youli Li, Myung Chul Choi, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya 2929-Pos Board B475 STRUCTURAL EVOLUTION OF ENERGY-CONSUMING TAU MEDIATED MICROTUBULE BUNDLES. Phillip A. Kohl , Bretton Fletcher, Chaeyeon Song, Peter J. Chung, Herbert P. Miller, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya

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