Biophysical Society 2020 Annual Meeting

Protein Structure and Conformation I (Boards B1 - B35) 170-Pos Board B1 UNDERSTANDING FUNCTION OF MITOCHONDRIAL HSP70 WITH IN OR- GANELLO SINGLE-MOLECULE FRET. Vanessa Trauschke , Rupa Banerjee, Dejana Mokranjac, Don C. Lamb 171-Pos Board B2 SQUEEZING PROTEINS AT THE UNFOLDING LIMIT. Prabhat Tripathi , Abdelkrim Bennabbas, Paul M. Champion, Meni Wanunu 172-Pos Board B3 LIQUID-OBSERVED VAPOR EXCHANGE (LOVE) NMR REVEALS RESIDUE- LEVEL EFFECTS OF PROTECTANTS ON A DRIED PROTEIN. Candice J. Crilly , Julia A. Noonan Brom, David A. Rockcliffe, Gary J. Pielak 173-Pos Board B4 Travel Awardee ATOMIC FORCE MICROSCOPY IMAGING REVEALS STRUCTURAL HETERO- GENEITIES IN COLLAGEN TYPE IV MOLECULES. Alaa Al-Shaer 174-Pos Board B5 THERMODYNAMICS OF PROTEIN-SURFACE BINDING - THE MODEL MAKES ALL THE DIFFERENCE. Nicholas C. Fitzkee , Kayla D. McConnell, Olivia C. Williams, Emily R. Chappell, Rebecca G. Manns 175-Pos Board B6 FROZEN IN TIME - HOW PHOSPHORYLATION INDUCES CONFORMA- TIONAL REARRANGEMENT IN THE CIRCADIAN AAA + ATPASE KAIC.  Colby R. Sandate , Jeffrey A. Swan, Carrie L. Partch, Gabriel C. Lander 176-Pos Board B7 Travel Awardee ON THE ROLE OF THE SOLVENT ENVIRONMENT IN THE FOLDING AND UNFOLDING OF AMPHIPATHIC HELICES. Natasha H. Rhys , Nicola Steinke, Samvid Kurlekar, Christian D. Lorenz, Sylvia E. McLain 177-Pos Board B8 PRESSURE PERTURBATION OF PROTEIN SECONDARY STRUCTURE COUPLED WITH MICROFLUIDIC MODULATION SPECTROSCOPY - A POWERFUL PLATFORM FOR BIOPHARMACEUTICAL FORMULATIONS DEVELOPMENT. Alexander Lazarev , Vera Gross, Libo Wang, Matthew McGann, Gary B. Smejkal, Nicole Cutri, Jeffrey A. Zonderman 178-Pos Board B9 MECHANICS OF ADHESION MOLECULES PROBED BY MOLECULAR DY- NAMICS AND HIGH-SPEED FORCE SPECTROSCOPY. Fidan Sumbul, Felix Rico 179-Pos Board B10 A SYSTEMATIC REVIEW OF CHROMOGRANIN A (CGA) AND ITS BIO- MEDICAL APPLICATIONS, UNVEILING ITS STRUCTURE-RELATED FUNC- TIONS. Manhyuk Han , Kyuhyung Choi, Seung Joong Kim 180-Pos Board B11 SPR AND HDXMS ANALYSIS OF INTERACTIONS BETWEEN COMPLEMENT COMPONENT 3 AND THROMBOMODULIN.  Julia R. Koeppe , Jose Giler 181-Pos Board B12 AMYLOID BETA OLIGOMERIZATION PROBED BY SINGLE-MOLECULE FRET. Fanjie Meng , Janghyun Yoo, Jae-Yeol Kim, Hoi Sung Chung 182-Pos Board B13 THE STRUCTURE AND MECHANISM OF A UNIQUE RIESKE-TYPE MONO- OXYGENASE ENZYME FROM THE HUMAN GUT MICROBIOTA IMPLI- CATED IN CARDIOVASCULAR DISEASE. Mussa Quareshy , Muralidharan Shanmugam, Alexander D. Cameron, Timothy D. Bugg, Yin Chen

183-Pos Board B14 STRUCTURAL INSIGHTS INTO AN ATP-DEPENDENT RIBOKINASE FROM ARABIDOPSIS THALIANA . Pyeoung-Ann Kang, Juntaek Oh, Haehee Lee, Claus-Peter Witte, Sangkee Rhee 184-Pos Board B15 MDMX ACIDIC DOMAIN REQUIRES THE WF MOTIF FOR THE INITIATION OF THE SECONDARY INTERACTION WITH THE P53DBD.  Malissa J. Fenton , Wade M. Borcherds, Gary W. Daughdrill, Lihong Chen, Jiandong Chen 185-Pos Board B16 STRUCTURE OF SMYBP-C M DOMAIN. Lindsey M. Hensley, Nathan T. Wright 186-Pos Board B17 PROBING LOCAL ENVIRONMENTS OF ADENYLATE KINASE WITH UN- NATURAL AMINO ACIDS. Angelica Camilo , Scott H. Brewer, Christine M. Phillips-Piro 187-Pos Board B18 THE ELUCIDATION OF THE FORMATION PROCESS OF ZEBRAFISH TAIL FIN BY 3D MODEL USING ADVANCED TRANS-SCALE EM AND BY CLEM. Jun- pei Kuroda, Takeshi Itabashi, Takako Ichinose, Shigeru Kondo, Atsuko H. Iwane 188-Pos Board B19 CRYSTAL STRUCTURE OF AN ANTI-CRISPR PROTEIN, ACRIF2, AND ITS INTERACTION WITH TYPE I-F CAS PROTEINS. Donghyun Ka, Nayoung Suh, Euiyoung Bae 189-Pos Board B20 UNRAVELING COMPLEX PROTEIN ENVIRONMENTS IN GREEN FLUORES- CENT PROTEIN USING THE UNNATURAL AMINO ACID 4-CYANO-L-PHE- NYLALANINE. Brianna M. Papoutsis , ByungUk Lee, Nathan Wong, Paul Nerenberg, Scott H. Brewer, Christine M. Phillips-Piro 190-Pos Board B21 ELUCIDATING THE STRUCTURE OF AGGREGATION-PRONE INTERMEDI- ATE CONFORMATIONS IN DIVERSE POINT MUTANTS OF HUMAN ΓD- CRYSTALLIN.  Jimmy Thai , Eugene Serebryany, Eugene Shakhnovich 191-Pos Board B22 STRUCTURAL AND FUNCTIONAL STUDIES ON A SMALL HEAT SHOCK PROTEIN FROM E. HISTOLYTICA . Devanshu Kurre 192-Pos Board B23 INTEGRATED STRUCTURAL DYNAMICS OF CALMODULIN.  Narendar Kolimi 193-Pos Board B24 Travel Awardee PORE FORMATION MECHANISM OF HUMAN GASDERMIN D. Shiyu Xia , Jianbin Ruan, Juan Lorenzo Pablo, Zhibin Zhang, Longfei Wang, Tian-Min Fu, Anna Greka, Judy Lieberman, Hao Wu 194-Pos Board B25 USING ALPHA SHAPES TO CHARACTERIZE PROTEIN PACKING AND CAPTURE THE MULTISCALE ASPECTS OF ALLOSTERY. Pranav M. Khade , Ambuj Kumar, Robert L. Jernigan 195-Pos Board B26 STRUCTURAL AND NANOMECHANICAL PROPERTIES OF GLYCATED COL- LAGEN FROMMOLECULES TO TISSUE. Dora Haluszka , Jolán Hársfalvi, Miklós S. Kellermayer 196-Pos Board B27 Travel Awardee THE FUNCTION OF LYNX1 AND LYNX2 PROTEIN IN BINDING AFFINITY TO NICOTINIC RECEPTORS AND GENE RESTORATION. Griffin M. Jones

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