Biophysical Society 2020 Annual Meeting

600-Pos Board B431 DESIGN AND OPTIMIZATION OF TROPOMYOSIN FRAGMENTS FOR TROPOMODULIN INTERACTION STUDIES. Balaganesh Kuruba , Dmitri Tol- katchev, Alla S. Kostyukova, Kyle Swain, Natalia Moroz, Trenton Williams, Kaitlin A. Smith 601-Pos Board B432 MONITORING PALLADIN’S EFFECT ON ACTIN DYNAMICS AND ORGANIZA- TION WITH TIRF MICROSCOPY. Abby Jurgensmeier , Moriah R. Beck 602-Pos Board B433 VISUALIZING DYNAMIC ACTIN CROSSLINKING PROCESSES DRIVEN BY THE ACTIN BINDING PROTEIN ANILLIN. Kyohei Matsuda , Mitsuhiro Sugawa, Masahiko Yamagishi, Noriyuki Kodera, Junichiro Yajima 603-Pos Board B434 ALTERATION OF MESENCHYMAL STEM CELLS POLARITY BY LAMINAR SHEAR STIMULATION PROMOTING Β-CATENIN NUCLEAR LOCALIZA- TION.  Jennifer Ho , Oscar K. Lee 604-Pos Board B435 DEEP LEARNING REVEALS THE LINK BETWEEN FILAMENT ARCHITECTURE AND SUBUNIT CONFORMATION IN BENT ACTIN. Matthew J. Reynolds , Rui Gong, Santiago Espinosa de los Reyes, Gregory M. Alushin 605-Pos Board B436 MICRORHEOLOGY OF ACTIVE ACTIN-MICROTUBULE NETWORKS.  Gloria Lee , Michael J. Rust, Moumita Das, Jennifer L. Ross, Rae Anderson 606-Pos Board B437 THE FORMIN INHIBITOR, SMIFH2, INHIBITS MEMBERS OF THE MYOSIN SUPERFAMILY.  James R. Sellers , Shidong Shi, Yukako Nishimura, Fang Zhang, Rong Liu, Yasuharu Takagi, Virgile Viasnoff, Alexander D. Bershad- sky 607-Pos Board B438 TALIN ROD MECHANICAL UNFOLDING: IN SILICO STUDY USING BOTH BOXED AND STEERED MOLECULAR DYNAMICS. Vasyl V. Mykuliak , Jona- than J. Booth, Dmitrii V. Shalashilin, Vesa P. Hytönen 608-Pos Board B439 ACTIN CONTROLS THE DYNAMICS AND MICROTUBULE CROSSLINKERS TUNE CO-LOCALIZATION IN CROSSLINKED COMPOSITE ACTIN-MICRO- TUBULE NETWORKS. Jennifer L. Ross, Shea N. Ricketts, Leila Farhadi , Moumita Das, Michael Rust, Rae Anderson 609-Pos Board B440 CONSERVED TRYPTOPHAN MUTATION LEADS TO DISCOVERY OF OBSCURE TYROSINATE FLUORESCENCE IN IMMUNOGLOBULIN DO- MAIN. Ravi Vattepu, Allan Ayella, Rachel Klausmeyer , Rahul Yadav, Joseph Dille, Moriah R. Beck 610-Pos Board B441 CYTOSKELETAL REGULATION OF THREE-DIMENSIONAL EPITHELIAL CELL SHAPE. Theresa A. Chmiel , Margaret L. Gardel 611-Pos Board B442 ACTIN DEPOLYMERIZATION AND COFILIN BINDING INDUCED BY DIELEC- TRIC ALLOSTERY.  Jun Ohnuki , Mitsunori Takano Bacterial Mechanics, Cytoskeleton, and Motility (Boards B443 - B455) 612-Pos Board B443 THE BACTERIAL TUBULIN HOMOLOG FTSZ FORMS 2D-SHEETS THAT SUS- TAIN ELECTRICAL OSCILLATIONS.  Julieta Bonacina , Monica P. Carabajal, María del Rocío Cantero, Horacio F. Cantiello

587-Pos Board B418 GEOMETRICAL CONSTRAINTS ASSOCIATED TO MECHANO-SENSING IN- DUCED DUAL-FILAMENT REGULATION IMPROVE IN-SILICO EXPLANATION OF POWER OUTPUT IN MUSCLE MODELLING. Lorenzo Marcucci , Hiroki Fukunaga, Mitsuhiro Iwaki, Toshio Yanagida 588-Pos Board B419 UNDERSTANDING OBSCURIN’S MOLECULAR MECHANISMS.  Charles J. White 589-Pos Board B420 INCREASED MICROTUBULE DENSITY AND ALTERED DIRECTIONALITY OCCUR COMMENSURATE WITH MYOFIBRILLAR MALFORMATION IN DYSTROPHIC AND AGED SKELETAL MUSCLE. Anicca Harriot , Andrew Cole- man, Guoli Shi, Humberto Cavalcante Joca, Christopher W. Ward 590-Pos Board B421 ISOLATED EXTENSOR DIGITORUM LONGUS MUSCLES FROM OLD MDX DYSTROPHIC MICE SHOW LITTLE FORCE RECOVERY 120 MINUTES AFTER ECCENTRIC DAMAGE. Leonit Kiriaev , Sindy Kueh, John W. Morley, Kath- ryn N. North, Peter J. Houweling, Stewart I. Head 591-Pos Board B422 TOWARD THE GENERAL MECHANISM FOR THICK AND THIN FILAMENT REGULATION OF THE SIMPLE HARMONIC MOTION OF TROPOMYOSIN IN THE ACTIVATION AND RELAXATION OF CONTRACTION IN CARDIAC, SKELETAL AND SMOOTH MUSCLES.  James J. Earley 592-Pos Board B423 TIMING AND LOAD-DEPENDENCE OF THE POWERSTROKE AND P I - RELEASE IN SKELETAL MUSCLE MYOSIN. Claudia Arbore , Francesco S. Pavone, Marco Capitanio, Edward P. Debold 593-Pos Board B424 THE ROLE OF THIN FILAMENT CALCIUM SENSITIVITY IN MODULATING RELAXATION TIME OF SOLEUS AND EDL SKELETAL MUSCLE. Connor Tyree , Kyra Peczkowski, Paul M. Janssen, Jill Rafael-Fortney, Jonathan P. Davis 594-Pos Board B425 INCREASING STIFFNESS OF COLLAGEN FIBERS CAN LEAD TO EXCESSIVE CONSTRICTION OF AIRWAYS. Ryan R. Jamieson , Suzanne E. Stasiak, Samuel R. Polio, Harikrishnan Parameswaran 595-Pos Board B426 DEPHOSPHORYLATION OF TONIC AND PHASIC SMOOTH MUSCLE MYOSIN IN THE IN VITRO MOTILITY ASSAY EXHIBITS DIFFERENT KINETICS.  Megan Hammell , Gijs Ijpma, Linda Kachmar, Anne-Marie Lauzon Actin Structure, Dynamics, and Associated Proteins (Boards B427 - B442) 596-Pos Board B427 CPI-MOTIF REGULATION OF BIOCHEMICAL FUNCTIONS OF ACTIN CAP- PING PROTEIN. Patrick McConnell, Marlene Mekel, Alexander G. Kozlov, Olivia L. Mooren, Timothy M. Lohman, John A. Cooper 597-Pos Board B428 QUANTIFICATION OF SURFACE RECEPTOR - ACTIN CORTEX INTERPLAY VIA MULTIPLEXED TWO - COLOR IMAGING. Aparajita Dasgupta , Huong-Tra Ngo, Deryl Tschoerner, Nicolas Touret, Bruno Da Rocha-Azevedo, Khuloud Board B429 ACTOMYOSIN CONTRACTILITY DRIVES INWARD BLEBBING BY CORRAL- LING MEMBRANE PROTEINS.  John Xiaohe Li , Bill Brieher 599-Pos Board B430 MYOSIN REGULATION OF ACTIN TURNOVER DYNAMICS. Danielle Scheff , Margaret L. Gardel Jaqaman 598-Pos

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