Biophysical Society 59th Annual Meeting Program Guide

1797-S ymp 4:30 pm IN VIVO-STUDIES OF GPCR CONFORMATIONAL CHANGES USING FLUORESCENCE-BASED ASSAYS. Martin Lohse 1798-S ymp 5:00 pm LIPID ORGANIZATION OF THE PLASMA MEMBRANE. Helgi I. Ingolfsson, Peter Tieleman, Siewert Marrink 1799-S ymp 5:30 pm DIFFERENTIAL PHOSPHATIDYLSERINE RECOGNITION BY THE TIM FAMILY OF IMMUNE REGULATORY RECEPTORS. Ka Yee C. Lee 4:00 pm –6:00 pm , B allroom II Symposium Extremophiles: Testing the Physical Limits of Living Systems Chair Catherine Royer, Rensselaer Polytechnic Institute 1800-S ymp 4:00 pm PROTEIN FOLDING AT EXTREME TEMPERATURES: CURRENT ISSUES. Georges Feller 1801-S ymp 4:30 pm USING SINGLE MOLECULE FORCE SPECTROSCOPY TO PROBE PROTEINS FROM EXTREMOPHILES. Lorna Dougan 1802-S ymp 5:00 pm MECHANISMS OF PRESSURE EFFECTS IN BIOLOGY: FROM PROTEINS TO LIVE BACTERIA. Catherine Ann Royer 1803-S ymp 5:30 pm WHAT LIMITS MICROBIAL GROWTH AT HIGH PRESSURE? Doug Bartlett 4:00 pm –6:00 pm , B allroom III Platform Optical Microscopy and Super-Resolution Imaging II Co-Chairs Luca Lanzano, Italian Institute of Technology, Italy Johan Elf, Uppsala University, Sweden 1804-P lat 4:00 pm BACKGROUND-FREE SUPER-RESOLUTION MICROSCOPY OF SUBCELLULAR STRUCTURES BY LIFETIME TUNING AND PHOTONS SEPARATION. Luca Lanzano , Ivan Coto Hernandez, Marco Castello, Enrico Gratton, Alberto Diaspro, Giuseppe Vicidomini 1805-P lat 4:15 pm INVESTIGATING CELLULAR FOCAL ADHESIONS ON NANO- PATTERNED SUBSTRATES WITH DUAL COLOR PHOTO- ACTIVATED LOCALIZATION MICROSCOPY. Hendrik G. Deschout , Michelle A. Baird, Michael W. Davidson, Joachim P. Spatz, Aleksandra Radenovic 1806-P lat 4:30 pm minority affairs travel awardee QUANTITATIVE ANALYSIS OF NANOSCALE LIPID BILAYER MODIFICATIONS VIA SECOND HARMONIC GENERATING PROBES. Erick K. Moen , Hope Beier, Andrea Armani, Bennett Ibey 1807-P lat 4:45 pm FUNCTIONAL IMAGING OF INTACT PANCREATIC ISLETS BY INVERTED SELECTIVE PLANE ILLUMINATION MICROSCOPY. Zeno Lavagnino , David W. Piston

1808-P lat 5:00 pm SINGLE MOLECULE TRACKING IN LIVING CELLS - MULTISTEP REACTIONS, SIMULATED MICROSCOPY AND NEW ANALYSIS METHODS. Martin Lindén, Johan Elf 1809-P lat 5:15 pm MAPPING THE DIFFUSIVE ROUTE OF NANOPARTICLES IN LIVE CELLS REVEALS SHAPE TO CONTROL NUCLEAR ACCESSIBILITY. Elizabeth Hinde , Hien T. Duong, Bunyamin Karagoz, Justin J. Gooding, Cyrille Boyer, Katharina Gaus 1810-P lat 5:30 pm CORRELATIVE IPALM AND PLATINUM REPLICA ELECTRON TOMOGRAPHY PINPOINTS ENDOCYTIC PROTEINS ON THE MAMMALIAN CELL CORTEX IN 3D. Kem A. Sochacki , Gleb Shtengel, Harald F. Hess, Justin W. Taraska 1811-P lat 5:45 pm REFSOFI FOR IMAGING PROTEIN-PROTEIN INTERACTIONS IN LIVING CELLS IN SUPER-RESOLUTION. Fabian Hertel , Gary Mo, Sam Duwé, Peter Dedecker, Jin Zhang OVEREXPRESSION OF FOXO IN THE HEART AMELIORATES PERFORMANCE DECLINE THROUGH ENHANCED UPS PROCESSING IN AGING DROSOPHILA. Anna C. Blice-Baum , Gaurav Kaushik, Meera C. Viswanathan, Alexander C. Zambon, Adam J. Engler, Rolf Bodmer, Anthony Cammarato 1813-P lat 4:15 pm OBSCURINS’ MECHANISTIC INVOLVEMENT IN SIGNAL TRANSDUCTION AT THE CARDIAC INTERCALATED DISC. Maegen Ackermann , Nicole Perry, Aikaterini Kontrogianni- Konstantopoulos 1814-P lat 4:30 pm THE N-TERMINAL HYPERVARIABLE REGION OF TROPONIN T DIFFERENTIALLY MODULATES THE AFFINITY OF TROPOMYOSIN-BINDING SITES. Chinthaka K. Amarasinghe , 4:45 pm CONSTITUTIVE PHOSPHORYLATION OF MYOSIN REGULATORY LIGHT CHAIN (RLC) IN VIVO IS MAINTAINED BY LOW KINASE AND PHOSPHATASE ACTIVITIES. Audrey N. Chang , Patrick M. Cowley, Anthony J. Baker, Kristine E. Kamm, James T. Stull 1816-P lat 5:00 pm EPIGALLOCATECHIN-3-GALLATE REVERSES THE DEFECTS IN MODULATION OF CA 2+ -SENSITIVITY BY TROPONIN I PHOSPHORYLATION CAUSED BY HYPERTROPHIC AND DILATED CARDIOMYOPATHY MUTATIONS IN CARDIAC MUSCLE. Maria Papadaki , Petr Vikhorev, Steven Marston, Andrew Messer Jian-Ping Jin 1815-P lat 4:00 pm –6:00 pm , B allroom IV Platform Cardiac Muscle Regulation Co-Chairs Maegen Ackermann, University of Maryland, Baltimore Michael Previs, University of Vermont 1812-P lat 4:00 pm

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland