Biophysical Society 59th Annual Meeting Program Guide

81-P lat 9:30 am NMR EVIDENCE FOR UNUSUAL BIFURCATED HYDROGEN BONDING IN THE TXXH ALPHA-HELIX N-CAPPING MOTIF. Matthew R. Preimesberger , Ananya Majumdar, Tural Aksel, Kevin Sforza, Doug Barrick, Juliette T.J. Lecomte 82-P lat 9:45 am OXIDATION INCREASES THE STRENGTH OF THE METHIONINE-AROMATIC INTERACTION. Andrew K. Lewis , Alessandro Cembran, Tiffany L. Senkow, Ryan Mahling, Gabriella T. Perell, Megan R. McCarthy, Cheng Her, Benjamin T. Horn, Christopher C. Valley, Christine B. Karim, Jiali Gao, William C. Pomerantz, David D. Thomas, Anne Hinderliter, Jonathan N. Sachs 83-P lat 10:00 am ELECTROSTATICS INSIDE THE SECY TRANSLOCON. Sara Capponi , Stephen H. White

8:15 am –10:15 am , R oom 314/315 Platform Ion Channels, Pharmacology, and Disease Co-Chairs David Busath, Bringham Young University Lyanne Schlichter, University of Toronto, Canada 92-P lat 8:15 am MOLECULAR DYNAMICS OF AMANTADINE BLOCK IN M2 OF INFLUENZA A: WT VS S31N. Mitchell L. Gleed, Harris Ioannidis, Antonios Kolocouris, David D. Busath 93-P lat 8:30 am POTENTIATION OF CFTR GATING BY AN ENERGETICALLY ADDITIVE MECHANISM. Han-I Yeh , Jiunn- Tyng Yeh, Tzyh-Chang Hwang 94-P lat 8:45 am AFFINITY CALCULATIONS FOR LIPOPHILIC MODULATORS BINDING TO ISOLATED SITES ON GABA(A) RECEPTORS. Sruthi Murlidaran , Reza Salari, Grace Brannigan 95-P lat 9:00 am SLC6A14 MODIFIES FLUID SECRETORY CAPACITY OF CYSTIC FIBROSIS AFFECTED EPITHELIUM BY ENHANCING CFTR CHANNEL FUNCTION. Saumel Ahmadi , Catherine Luk, Sunny Xia, Michelle Di Paola, Timothy Chung, Johanna Rommens, Christine Bear 96-P lat 9:15 am ENHANCED ACTIVATION OF AN AMINO-TERMINALLY TRUNCATED ISOFORM OF VOLTAGE-GATED PROTON CHANNEL HVCN1 ENRICHED IN MALIGNANT B CELLS. Elayne Hondares, Mark Brown, Boris Musset, Deri Morgan, Vladimir V. Cherny, Christina Taubert, Mandeep K. Bhamrah, David Coe, Federica Marelli-Berg, John G. Gribben, Martin JS Dyer, Melania Capasso, Thomas E. DeCoursey 97-P lat 9:30 am POSITIVE KCA CHANNEL GATING MODULATORS WITH SELECTIVITY FOR KCA3.1. Brandon M. Brown , Nichole Coleman, Vladimir Yarov-Yarovoy, Heike Wulff 98-P lat 9:45 am EXPRESSION AND CONTRIBUTIONS OF TRPM7 AND KCA2.3/SK3 CHANNELS TO THE INCREASED MIGRATION AND INVASION OF MICROGLIA IN ANTI-INFLAMMATORY ACTIVATION STATES. Tamjeed Siddiqui, Starlee Lively, Roger Ferreira, Raymond Wong, Lyanne Schlichter 99-P lat 10:00 am ATOMIC BASIS FOR POTASSIUM CHANNEL POTENTIATION BY A NOVEL CLASS OF ANTI-EPILEPTIC DRUGS. Robin Y. Kim , Michael C. Yau, Stephan A. Pless, Jason D. Galpin, Christopher A. Ahern, Harley T. Kurata

8:15 am –10:15 am , R oom 309/310 Platform Membrane Physical Chemistry I

Co-Chairs Rumiana Dimova, Max Planck Institute of Colloids and Interfaces, Germany Ilya Levental, University of Texas Health Medical Center 84-P lat 8:15 am

DIFFERENTIATION OF PLASMA MEMBRANE COMPOSITION AND PHYSICAL PROPERTIES. Ilya Levental , Kandice R. Levental 85-P lat 8:30 am REAL-TIME IMAGING OF NANOSCOPIC LIPID DOMAINS USING ISCAT. Gabrielle de Wit, John S. H. Danial, Philipp Kukura, Mark I. Wallace 86-P lat 8:45 am A FUNDAMENTAL FORCE THAT REGULATES NANO- CLUSTERING OF PROTEINS IN BIOLOGICAL MEMBRANES. Kranthi Kiran Mandadapu , Shachi Katira, Suriyanarayanan Vaikuntanathan, Berend Smit, David Chandler 87-P lat 9:00 am THEORY OF REGISTERED AND ANTIREGISTERED PHASE SEPARATION IN MIXED AMPHIPHILIC BILAYERS. John J. Williamson , Peter D. Olmsted 88-P lat 9:15 am HOW GM1 AFFECTS THE PHASE STATE AND MECHANICAL PROPERTIES OF PHOSPHOLIPID MEMBRANES. Nico Fricke, Rumiana Dimova 89-P lat 9:30 am EXAMINING THE EFFECTS OF CHOLESTEROL: LAURDAN AND PATMAN SEE IT DIFFERENTLY. Emma R. Moulton , Kelsey J. Hirsche, Monica L. Hobbs, Morgan M. Schwab, John D. Bell 90-P lat 9:45 am ORIENTATIONAL TEXTURE OF MEMBRANE DOMAINS: EFFECT OF LIPID COMPOSITION AND BINDING OF A BACTERIAL TOXIN. Adam C. Simonsen , Jes Dreier, Vita Solovyeva, Jonas C. Jeppesen, Jonathan Brewer 91-P lat 10:00 am PLASMA MEMBRANE VESICLE CRITICAL TEMPERATURE SCALES WITH GROWTH TEMPERATURE IN A ZEBRAFISH CELL LINE. Margaret Burns, Jing Wu, Kathleen Wisner, Sarah Veatch

8:15 am –10:15 am , R oom 316/317 Platform Kinesins, Dyneins, and Other MT-based Motors

Co-Chairs Sarah Rice, Northwestern University Etsuko Muto, Riken Brain Science Institute, Japan 100-P lat 8:15 am KINESIN-5 ACTS AS A MICROTUBULE STABILIZER, POLYMERASE AND PLUS-TIP TRACKER. Yalei Chen, William O. Hancock

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland