Biophysical Society 59th Annual Meeting Program Guide

2505-P lat 9:45 am HIV-TAT PROTEIN-AMYLOID BETA COMPLEX: FROM MOLECULAR INTERACTION TO INCREASED NEUROTOXICITY. Alina Popescu Hategan , Joseph Steiner, Mario A. Bianchet, Elena Karnaukhova, Emilios K. Dimitriadis, Avindra Nath 2506-P lat 10:00 am THE INTRINSICALLY DISORDERED MEMBRANE ENZYMES SELENOPROTEIN S AND SELENOPROTEIN K. Liu Jun, zhengqi Zhang, Sharon Rozovsky 8:15 am –10:15 am , R oom 314/315 Platform Membrane Active Peptides and Toxins Co-Chairs Patricia Clark, University of Notre Dame B. Scott Perrin, NIH/NHLBI 2507-P lat 8:15 am MULTIPLE DRIVING FORCES CONTRIBUTE TO TRANSLOCATION OF AUTOTRANSPORTER VIRULENCE PROTEINS. Igor Drobnak, Esther Braselmann, Patricia L. Clark 2508-P lat 8:30 am DECIPHERING PROTEIN MEMBRANE INTERACTIONS INVOLVED IN THE TRANSLOCATION PROCESS OF A BACTERIAL TOXIN, THE ADENYLATE CYCLASE (CYAA) TOXIN FROM B. PERTUSSIS. Orso Subrini, Johanna Karst, Ana-Cristina Sotomayor-Pérez, Audrey Hessel, Edithe Selwa, Nicolas Sapay, Rémi Veneziano, Jonathan Pansieri, Joel Chopineau, Daniel Ladant, Alexandre Chenal 2509-P lat 8:45 am MOVING ALONG THE FREE ENERGY LANDSCAPE OF MEMBRANE INSERTION OF THE DIPHTHERIA TOXIN TRANSLOCATION DOMAIN. Mauricio Vargas-Uribe , Mykola V. Rodnin, Alexander Kyrychenko, Alexey S. Ladokhin 2510-P lat 9:00 am ASSESSING THE TRANSLOCATION OF CPPS USING FORCE MEASUREMENT, SINGLE MOLECULES AND EMULSIONS. Pierre Soule , Abdou Rachid Thiam, Frédéric Pincet, Alain Joliot, Sandrine Sagan, Sophie Cribier, Nicolas Rodriguez 2511-P lat 9:15 am SYNTHETIC MOLECULAR EVOLUTION APPROACH: DISCOVERY AND CHARACTERIZATION OF NOVEL ANTIVIRAL PEPTIDES. Jing He , Gregory Wiedman, Kalina Hristova, William C. Wimley 2512-P lat 9:30 am PORE FORMATION MECHANISMS OF MELITTIN-LIKE MEMBRANE-ACTIVE PEPTIDES. Charles H. Chen , Gregory Wiedman, Yukun Wang, Ayesha Khan, Martin B. Ulmschneider 2513-P lat 9:45 am THE CURVATURE INDUCTION OF SURFACE-BOUND ANTIMICROBIAL PEPTIDES PISCIDIN 1 AND PISCIDIN 3 VARIES WITH LIPID CHAIN LENGTH. Bradley S. Perrin , Alexander J. Sodt, Myriam L. Cotten, Richard W. Pastor 2514-P lat 10:00 am A GENERAL MECHANISM FOR OFF-TARGET EFFECTS: STUDIES WITH AMIODARONE AND OTHER ANTIARRHYTHMICS. Radda Rusinova , Roger E. Koeppe II, Olaf S. Andersen

9:00 am –1:00 pm , H all C Biomolecular Discovery Dome

W E

Visit this 3-D portable Dome, sponsored by the Public Affairs Committee, to see how difficult biophysical topics can be made accessible to high school students and the public. Short videos that communicate the excitement of looking at macromolecular complexes and understanding the molecular basis for life are being shown throughout the week. 10:30 am –11:15 am , H all C Coffee Break 12:00 pm –3:00 pm , R oom 333 Publications Committee Meeting 1:00 pm –3:00 pm , B allroom I Symposium Advances in Electron Microscopy Chair Yifan Cheng, University of California, San Francisco 2515-S ymp 1:00 pm CRYO-EM OF DNA REPAIR PROTEIN COMPLEXES. Hong-Wei Wang 2516-S ymp 1:30 pm STRUCTURAL MATURATION OF HEPATITIS B CORE PROTEIN CAPSIDS. Bettina Boettcher 2517-S ymp 2:00 pm SINGLE PARTICLE CRYO-EM OF CALCIUM RELEASE CHANNELS. Irina I. Serysheva 2518-S ymp 2:30 pm SINGLE PARTICLE CRYOEM OF INTEGRAL MEMBRANE PROTEINS. Yifan Cheng

D N

E S

D A Y

1:00 pm –3:00 pm , B allroom II Symposium Catalysis in the Membrane

Chair Jochen Zimmer, University of Virginia 2519-S ymp 1:00 pm

ZMPSTE24 AND PREMATURE AGEING: A UNIQUE INTEGRAL MEMBRANE METALLOPROTEASE WITH A HOLE IN THE MIDDLE. Liz Carpenter 2520-S ymp 1:30 pm THE MECHANISM OF RHOMBOID INTRAMEMBRANE PROTEASE. Ya Ha 2521-S ymp 2:00 pm CLEAVAGE-DEPENDENT AND INDEPENDENT ROLE OF THE SERINE PROTEASE CAP1/PRSS8. Edith Hummler 2522-S ymp 2:30 pm A MOLECULAR DESCRIPTION OF CELLULOSE BIOSYNTHESIS. Jochen Zimmer

149

Biophysical Society 59 th Annual Meeting, Baltimore, Maryland