Biophysical Society 59th Annual Meeting Program Guide

2532-P lat

1:15 pm

1:00 pm –3:00 pm , B allroom III Platform Protein-Lipid Interactions III

international travel awardee

SURPRISING ABUNDANCE OF MISFOLDING DURING REFOLDING OF MULTIDOMAIN PROTEINS. Alessandro Borgia , Katherine R. Kemplen, Madeleine B. Borgia, Robert B. Best, Andrea Soranno, Daniel Nettels, Bengt Wunderlich, Jane Clarke, Benjamin Schuler 2533-P lat 1:30 pm TWO-DIMENSIONAL FLUORESCENCE LIFETIME CORRELATION SPECTROSCOPY ON THE FOLDING MECHANISM OF B DOMAIN OF PROTEIN A. Takuhiro Otosu , Kunihiko Ishii, Hiroyuki Oikawa, Munehito Arai, Satoshi Takahashi, 1:45 pm CONFORMATIONAL DYNAMICS OF MOLECULAR CHAPERONES INVESTIGATED BY SINGLE MOLECULE MULTICOLOR FÖRSTER RESONANCE ENERGY TRANSFER. Lena Voith von Voithenberg , Anders Barth, Swati Tyagi, Christine Koehler, Edward A. Lemke, Don C. Lamb 2535-P lat 2:00 pm COPPER AND ZINC BINDING SPECIFICALLY INDUCE THE AGGREGATION OF HUMAN Γ -D CRYSTALLIN. Liliana Quintanar , Evgene Serebryany, Jose Antonio Domínguez-Calva, Cameron Haasse-Pettingell, Jonathan A. King 2536-P lat 2:15 pm education travel awardee ROLE OF PORE LOOPS IN THE MECHANISM OF POLYPEPTIDE TRANSLOCATION BY A AAA+ PROTEASE MACHINE. Piere Rodriguez-Aliaga , Luis E. Ramirez, Frank Kim, Andreas Martin, Carlos Bustamante 2537-P lat 2:30 pm (DIS)ASSEMBLY AND STRUCTURAL STABILITY OF MTHSP60 AND ITS PRECURSOR NAÏVE FORM. Dario Spigolon , Silvia Vilasi, Maria Rosalia Mangione, PierLuigi San Biagio, Donatella Bulone 2538-P lat 2:45 pm CHARACTERIZING THE CONFORMATIONAL ENSEMBLES OF THE E. COLI HSP70, DNAK REVEALS THE ROLE OF THE INTERMEDIATE STATE. Alex Liqi Lai , Mandy Blackburn, Eugenia M. Clerico, Peter Borbat, Lila M. Gierasch, Jack H. Freed Tahei Tahara 2534-P lat

Co-Chairs Renee JiJi, University of Missouri James Sturgis, Aix-Marseille Université, France 2523-P lat 1:00 pm

ELUCIDATING THE INTERACTION OF 5-LIPOXYGENASE AND FLAP. Ramakrishnan B.Kumar , Hans Hebert, Caroline Jegerschöld 2524-P lat 1:15 pm DESTABILIZING AQUAPORIN Z ASSEMBLY: EFFECTS ON STRUCTURE, FUNCTION AND DYNAMICS. Victoria Schmidt, Pierre Hubert, Valerie Prima, James Sturgis 2525-P lat 1:30 pm THE ROLE OF LIPID ENVIRONMENT ON PEPTIDE STRUCTURE AND FOLDING. Renee D. JiJi , Jian Xiong, Anahita Zare, Jason W. Cooley 2526-P lat 1:45 pm INVESTIGATION ON THE INTERACTION BETWEEN PLEXIN INTRACELLULAR PLUS TRANSMEMBRANE DOMAINS WITH GTPASES AND WITH THE LIPID BILAYER USING ALL-ATOM MOLECULAR DYNAMICS SIMULATIONS. Liqun Zhang , Buck Matthias 2527-P lat 2:00 pm ROLE OF PHOSPHOLAMBAN MUTATIONS IN PROTEIN- PROTEIN INTERACTIONS. Vitaly V. Vostrikov , Kailey J. Soller, Kim N. Ha, Sarah E. Nelson, Tata Gopinath, Gianluigi Veglia 2528-P lat 2:15 pm SINGLE-MOLECULE FRET DETECTION OF GXXXG-MEDIATED TRANSMEMBRANE HELIX-HELIX INTERACTIONS. Yoshiaki Yano , Kotaro Kondo, Katsumi Matsuzaki 2529-P lat 2:30 pm SPONTANEOUS RECONSTITUTION OF BOVINE RHODOPSIN INTO ARTIFICIAL MEMBRANES. Udeep Chawla , Wan Zheng, Liangju Kuang, Yunjiang Jiang, Suchithranga M. D. C. Perera, Michael F. Brown, Hongjun Liang 2530-P lat 2:45 pm COARSE-GRAINED MODELING OF MINUTE-TIMESCALE CO- TRANSLATIONAL MEMBRANE PROTEIN INTEGRATION VIA THE SEC-TRANSLOCON. Michiel J.M. Niesen , Thomas F. Miller III

1:00 pm –3:00 pm , R oom 307/308 Platform Excitation-Contraction Coupling

Co-Chairs Benjamin Prosser, University of Pennsylvania William Louch, University of Oslo, Norway 2539-P lat 1:00 pm

1:00 pm –3:00 pm , B allroom IV Platform Protein Folding and Chaperones

IDENTIFICATION OF A CALSEQUESTRIN-1 MUTATION IN A HUMAN VACUOLAR MYOPATHY. Daniela Rossi , Bianca Vezzani, Valeria Del Re, Virginia Barone, Simone Spinozzi, Alessandra Gamberucci, Stefania Lorenzini, Cecilia Paolini, Feliciano Protasi, Carlo Reggiani, Vincenzo Sorrentino, Lucia Galli 2540-P lat 1:15 pm MICROTUBULE DETYROSINATION MODULATES STRETCH- DEPENDENT X-ROS SIGNALING IN HEART. Patrick G. Robison, Jaclyn P. Kerr, Alexey I. Bogush, Daniel A. Harki, Christopher W. Ward, Benjamin L. Prosser

Co-Chairs Wilfredo Colon, Rensselaer Polytechnic Institute Liliana Quintanar, Cinvestav, Mexico 2531-P lat 1:00 pm

PROTEOMICS-LEVEL IDENTIFICATION OF DEGRADATION- RESISTANT PROTEINS PROVIDE INSIGHT ABOUT THEIR POTENTIAL ROLES IN ORGANISMAL ADAPTATION TO STRESS. Ke Xia, Jennifer Wilcox, Kayleigh Kobovitch, Brian Ortiz, Areeg Khalil, Wilfredo Colon

150

Biophysical Society 59 th Annual Meeting, Baltimore, Maryland