Biophysical Society 59th Annual Meeting Program Guide

2660-P os B oard B90 MORPHOLOGY SELECTION THROUGH GEOMETRIC FRUSTRATION IN TWISTED FILAMENT BUNDLES AND FIBERS. Doug Hall, Isaac R. Bruss , Justin Barone, Gregory M. Grason 2661-P os B oard B91 NOVEL SINGLE-MOLECULE RESOLUTION METHOD FOR SPATIO-TEMPORAL SIMULATIONS OF PROTEIN BINDING AND RECRUITMENT ON THE MEMBRANE. Osman N. Yogurtcu , Margaret E. Johnson 2662-P os B oard B92 STOICHIOMETRY AS A KEY MODULATOR OF PIP PLANT AQUAPORINS BIOLOGICAL ACTIVITY. Cintia Jozefkowicz , Lorena Sigaut, Agustina Canessa Fortuna, Florencia Scochera, Luis González Flecha, Lia I. Pietrasanta, Nicolás D. Ayub, Gabriela Soto, Gabriela Amodeo, Karina Alleva 2663-P os B oard B93 LANDSCAPES OF MEMBRANE PROTEIN INTERACTIONS FROM HIGH-THROUGHPUT MD SIMULATIONS USING THE DAFT APPROACH. Tsjerk A. Wassenaar , Kristyna Pluhackova, Anastassiia Moussatova, Durba Sengupta, Siewert J. Marrink, D. Peter Tieleman, Rainer A. Böckmann 2664-P os B oard B94 INCREASED SIGNALING EFFICIENCY OF CONVENTIONAL PKC THROUGH SELF-ASSEMBLED CLUSTERING ON THE PLASMA MEMBRANE. Xin Hui, Mike Bonny, Lars Kaestner, Karsten Kruse, Peter Lipp 2665-P os B oard B95 DEVELOPMENT OF TOOLS TO STUDY RETROVIRAL GAG ASSEMBLY ON GIANT UNILAMELLAR VESICLES(GUV). Yi Wen , Robert Dick, Volker Vogt, Gerald Feigenson 2666-P os B oard B96 PARADIGM SHIFT IN THE MECHANISM OF HIV-1 CORE BIOGENESIS. Gabriel A. Frank , Kedar Narayan, Julian W. Bess Jr, Gregory Q. Del Prete, Xiongwu Wu, Amy Moran, Lisa Hartnell, Lesley A. Earl, Jeffrey D. Lifson, Sriram Subramaniam 2667-P os B oard B97 education travel awardee MOLECULAR DYNAMICS AND ASSEMBLY SWITCH OF FTSZ FILAMENTS. Erney Ramírez-Aportela , José Ramón López-Blanco, José Manuel Andreu, Pablo Chacon 2668-P os B oard B98 STRUCTURAL AND BIOPHYSICAL COMPARISON OF UPEC AND ETEC ADHESION FIMBRIAE. Narges Mortezaei, Bhupender Singh, Esther Bullitt , Johan Zakrisson, Chelsea R. Epler, Krister Wiklund, Magnus Andersson Protein Dynamics and Allostery III (Boards B99-B116) 2669-P os B oard B99 PROPOSED THERMODYNAMIC BASIS FOR SYNAPTOTAGMIN RESPONSE. Anne Hinderliter 2670-P os B oard B100 ALLOSTERIC FUNCTIONAL SWITCH IN POLIOVIRUS 3C PROTEASE. Yan M. Chan , David D. Boehr 2671-P os B oard B101 THE STRUCTURAL BASIS OF ATP AS AN ALLOSTERIC MODULATOR. Shaoyong Lu , Wenkang Huang, Qi Wang, Qiancheng Shen, Shuai Li, Ruth Nussinov, Jian Zhang

Protein Assemblies II (Boards B77-B98) 2647-P os B oard B77 ASSEMBLY OF THE RIG-I 2CARD SIGNALING COMPLEX. David Mouser 2648-P os B oard B78 CHARACTERIZATION OF THE MDA5 2CARD SIGNALING COMPLEX. Cassie Zerbe , James Cole 2649-P os B oard B79 DETAILED MECHANISM OF RAPID AMYLOID FIBRIL SELF- ASSEMBLY DUE TO SURFACE DIFFUSION. Yi-Chih Lin , E. James Petersson, Zahra Fakhraai 2650-P os B oard B80 CO-AGGREGATION OF ALPHA-SYNUCLEIN WITH AMYLIN(HIAPP) LEADS TO AN INCREASED RISK IN TYPE II DIABETES PATIENTS FOR DEVELOPING PARKINSON’S DISEASE. Yoav Atsmon-Raz , Yifat Miller 2651-P os B oard B81 INSIGHT INTO THE METAL BINDING SITES IN AMYLIN AGGREGATES. Vered Wineman-Fisher, Yifat Miller 2652-P os B oard B82 CHARACTERIZING KINETIC INTERMEDIATE IN AMYLOID SELF-ASSEMBLY. Chen Liang 2653-P os B oard B83 SITE-SPECIFIC STRUCTURAL CHANGES IN UNMODIFIED AND PYROGLUTAMYLATED AMYLOID BETA PEPTIDE BY ISOTOPE-EDITED FTIR. Greg Goldblatt , Jason O. Matos, Jeremy Gornto, Laura N. Puentes, Angel Docobo, Suren A. Tatulian 2654-P os B oard B84 PREPARATION PROTOCOLS OF BETA-AMYLOID (1- 40) PROMOTE THE FORMATION OF POLYMORPHIC AGGREGATES AND ALTERED INTERACTIONS WITH LIPID BILAYERS. Elizabeth A. Yates , Justin Legleiter 2655-P os B oard B85 THERMODYNAMICS OF ABETA(16-21) DISSOCIATION FROM AN AMYLOID FIBRIL. Cristiano L. Dias , Srinivasa Rao Jampani 2656-P os B oard B86 A COMPUTATIONAL STUDY OF AMYLOID β -PROTEIN ASSEMBLY IN CROWDED ENVIRONMENTS. Matthew J. Voelker , Brigita Urbanc, Mark Betnel 2657-P os B oard B87 TRANSITION OF AMYLOID OLIGOMERS TO MATURE FIBRILS: INTERNAL CONVERSION VS. COMPETING ASSEMBLY PATHWAYS? Tatiana Miti , Mentor Mulaj, Martin Muschol 2658-P os B oard B88 STRUCTURAL VARIATIONS OF AMYLOID β -PROTEIN FIBRILS SEEDED WITH EXTRACTED FIBRILS FROM BRAIN TISSUE OF ALZHEIMER’S DISEASE MODEL MICE. Hiroaki Komatsu , Paul H. Axelsen 2659-P os B oard B89 DETERMINATION OF NUCLEATION MASS FOR AMYLOID- β AGGREGATION. Preetam Ghosh, Amit Kumar, Vijayaraghavan Rangachari, Ashwin Vaidya

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland