Biophysical Society 59th Annual Meeting Program Guide

10:45 am –12:45 pm , B allroom I Symposium New and Notable

10:45 am –12:45 pm , B allroom III Platform Voltage-gated K Channels I

Co-Chairs Enrique De La Cruz, Yale University Karen Fleming, Johns Hopkins University N o A bstract 10:45 am SINGLE MOLECULE MECHANICS – TOWARDS HIGH THROUGHPUT. Michelle Wang N o A bstract 11:02 am TRANSPORT THROUGH CARBON NANOTUBE PORINS IN LIPID MEMBRANES. Aleksandr Noy N o A bstract 11:19 am MECHANISMS OF EBOLA VIRUS IMMUNE EVASION. Gaya Amarasinghe N o A bstract 11:36 am A VIRUS THAT INFECTS A HYPERTHERMOPHILE ENCAPSIDATES A-FORM DNA. Frank DiMaio N o A bstract 11:53 am MECHANISMS OF AMPA RECEPTOR ACTIVATION AND DESENSITIZATION INVESTIGATED BY X-RAY CRYSTALLOG- RAPHY, DEER AND CRYO-ELECTRON MICROSCOPY. Katharina Duerr N o A bstract 12:10 pm RHEOSTATS AND TOGGLE SWITCHES FOR MODIFYING PROTEIN FUNCTION. Liskin Swint-Kruse N o A bstract 12:27 pm THE PRINCIPLES OF LIPID SCRAMBLING: STRUCTURAL IN- SIGHTS FROM A TMEM16 FAMILY MEMBER. Janine Brunner 10:45 am –12:45 pm , B allroom II Symposium Systems Biology Approaches in Neuroscience Chair Kristin Branson, Howard Hughes Medical Institute 108-S ymp 10:45 am MAPPING BEHAVIOR TO NEURAL ANATOMY USING MACHINE VISION AND THERMOGENETICS. Kristin Branson , 11:15 am VARIABILITY, ROBUSTNESS AND HOMEOSTASIS IN NEURONS AND NETWORKS. Eve Marder 109-S ymp 11:45 am IMAGING THE CONNECTOME. Jeff Lichtman N o A bstract 12:15 pm SPACE-TIME WIRING SPECIFICITY SUPPORTS DIRECTION SELECTIVITY IN THE RETINA. Sebastian Seung Alice A. Robie N o A bstract

Co-Chairs Timothy Jegla, Pennsylvania State University Ramon LaTorre, University of Valparaíso, Chile 110-P lat 10:45 am

international travel awardee

INTERACTION OF CALMODULIN WITH THE EAG1 POTASSIUM CHANNEL. Maria J. Marques-Carvalho , João H. Morais-Cabral 111-P lat 11:00 am EFFECTS OF THE ACCESSORY SUBUNIT Γ 1 ON THE EXTERNAL ARCHITECTURE OF BK CHANNEL. Willy Carrasquel-Ursulaez , Juan P. Castillo, Yenisleidy Lorenzo, Romina Sepulveda, Daniel Aguayo, Francisco Bezanilla, Fernando D. Gonzalez-Nilo, Ramon Latorre 112-P lat 11:15 am ENHANCED VOLTAGE-CLAMP FLUOROMETRY ASSIGNS DISTANCE CONSTRAINTS TO BK CHANNEL VSD STRUCTURAL TRANSITIONS. Antonios Pantazis , Riccardo Olcese 113-P lat 11:30 am international travel awardee CALMODULIN BINDING TO A NOVEL SITE IN THE AB MODULE OF KV7.2 SUBUNITS REGULATES SURFACE EXPRESSION. Ganeko Bernardo-Seisdedos , Juncal Fernandez-Orth, Carolina Gomis-Perez, Alessandro Alaimo, Araitz Alberdi, Covadonga Malo, Pilar Areso, Alvaro Villarroel 114-P lat 11:45 am A POINT MUTATION CAUSING EPISODIC ATAXIA REVEALS FUNCTIONAL LINK BETWEEN VOLTAGE SENSOR AND SELECTIVITY FILTER IN SHAKER KV CHANNELS. Dimitri Petitjean, Rikard Blunck 115-P lat 12:00 pm EVOLUTIONARY ORIGINS OF THE SHAKER FAMILY OF VOLTAGE-GATED POTASSIUM CHANNELS. Xiaofan Li , Hansi Liu, Sarah A. Rhodes, Liana Trigg, Fortunay H. Diatta, Jessica K. Sassic, David K. Simmons, Mark Q. Martindale, Timothy Jegla 116-P lat 12:15 pm ALTERNATIVE SPLICING MODULATES KV CHANNEL CLUSTERING THROUGH A MOLECULAR ׳ BALL AND CHAIN ׳ MECHANISM. Nitzan Zandany, Shir Marciano, Elhanan Magidovich, Rinat Yehezkel, Tzilhav Shem-Ad, Limor Lewin, Uri Abdu, Irit Orr, Ofer Yifrach 117-P lat 12:30 pm minority affairs travel awardee BETA-2 AND GAMMA-1 AUXILIARY SUBUNITS COASSEMBLE IN THE SAME BK CHANNEL AND INDEPENDENTLY CONTRIBUTE TO REGULATION OF CHANNEL GATING. Vivian M. Gonzalez-Perez , Xiao-Ming Xia, Christopher J. Lingle

16

Biophysical Society 59 th Annual Meeting, Baltimore, Maryland