Biophysical Society 59th Annual Meeting Program Guide

2782-P os B oard B212 MOLECULAR DYNAMICS SIMULATIONS REVEAL

Membrane Active Peptides and Toxins II (Boards B201-B227) 2771-P os B oard B201 THE PRESENCE OF ANTIPARALLEL BETA-SHEETS IN TOXIC FIBRILS FORMED BY ABETA ON GM1 CLUSTERS. Yuki Okada, Hiroshi Ueno, Yoshiaki Yano, Masaru Hoshino, Hikari Itoh-Watanabe, Akira Naito, Katsumi Matsuzaki 2772-P os B oard B202 STRUCTURAL TRANSFORMATION OF AMYLOID PEPTIDES INTERACTING WITH LIPID MEMBRANES. Yen Sun, Huey W. Huang 2773-P os B oard B203 ALPHA-SYNUCLEIN STABILIZES SMALL UNILAMELLAR VESICLES BY REDUCING BOTH MEMBRANE SURFACE TENSION AND RIGIDITY. Anthony R. Braun , Jonathan N. Sachs 2774-P os B oard B204 MEMBRANES CAN FINELY TUNE PEPTIDE-INDUCED LIPID EXTRACTION BY MODULATING THEIR LIPID COMPOSITION. Alexandre Therrien, Michel Lafleur 2775-P os B oard B205 MECHANISM OF ACTION OF β -HAIRPIN ANTIMICROBIAL PEPTIDES. Richard B. Lipkin , Themis Lazaridis 2776-P os B oard B206 ATTACK ON SINGLE ESCHERICHIA COLI SPHEROPLASTS BY ANTIMICROBIAL PEPTIDES. Tzu-Lin Sun , Yen Sun, Huey W. Huang 2777-P os B oard B207 INSIGHTS INTO THE EFFECTS OF ANTIMICROBIAL PEPTIDES ON LIVE E. COLI CELLS USING TIME-LAPSE FLUORESCENCE MICROSCOPY. Ranga Rajan , James C. Weisshaar 2778-P os B oard B208 HISTIDINE-RICH DESIGNER PEPTIDES WITH PH- DEPENDENT MEMBRANE TOPOLOGY, ANTIMICROBIAL, NUCLEIC ACID TRANSFECTION AND VIRAL TRANSDUCTION CAPABILITIES. Christopher Aisenbrey, Philippe Bertani, Andrea Farrotti, David Fenard, Anne Galy, Elise Glattard, Arnaud Marquette, Jesus Raya, Evgeniy S. Salnikov, Joachim Seelig, Lorenzo Stella, Louic Vermeer, Nathaliia Voievoda, Burkhard Bechinger 2779-P os B oard B209 EFFECT OF HISTIDINE RICH ANTIMICROBIAL PEPTIDES,GAD-1 AND GAD-2,ON MODEL MEMBRANES AT DIFFERENT PH VALUES. Gagandeep K. Sandhu , Michael R. Morrow, Valerie Booth 2780-P os B oard B210 THE TRANSMEMBRANE STATE OF ANTIMICROBIAL PISCIDIN IN BACTERIAL CELL MEMBRANE MIMICS DRAMATICALLY ALTERS THE POLAR-NONPOLAR SEGREGATION OF THE BILAYER. Myriam Cotten , Jorge I. Hernandez, Kimberly Bogardus, Mihaela Mihailescu 2781-P os B oard B211 ANTIMICROBIAL PEPTIDE PISCIDIN PERMEABILIZES BACTERIAL MEMBRANES AND BINDS INTRACELLULAR TARGETS AT SUB-LETHAL CONCENTRATIONS. Mason Schoeneck , Robert Hayden, Gina Goldberg, Bryan Ferguson, Michael McCormick, Herman Lehman, Myriam Cotten

MECHANISTIC DETAILS OF POLYMYXIN PENETRATION INTO BOTH MEMBRANES OF E.COLI. Syma Khalid , Nils A. Berglund, Peter J. Bond, Thomas J. Piggot 2783-P os B oard B213 THERMODYNAMICS GOVERN THE MECHANISM OF ANTIMICROBIAL LIPOPEPTIDES: INSIGHTS FROM COARSE- GRAINED MOLECULAR DYNAMICS SIMULATIONS. Dejun Lin , Alan Grossfield 2784-P os B oard B214 THE NATURE OF DAPTOMYCIN AGGREGATES. Ming-Tao Lee , Wei-Chin Hung, Yen-Fei Chen, Huey W. Huang 2785-P os B oard B215 LIPID SELECTIVITY OF FUNGICIDAL LIPOPEPTIDES. Sebastian Fiedler , Quang Huynh, Hiren Patel, Heiko Heerklotz 2786-P os B oard B216 STRUCTURE AND MEMBRANE TOPOLOGY OF THE PORE- FORMING PEPTIDE MACULATIN 1.1. Marc-Antoine Sani , Terry P. Lybrand, Frances Separovic 2787-P os B oard B217 STRUCTURE OF TRANSMEMBRANE PORES STABILIZED BY ANTIMICROBIAL PEPTIDES MAGAININ AND PGLA. Almudena Pino Angeles , John M. Leveritt III, Themis Lazaridis 2788-P os B oard B218 MODULATION OF THE INTERACTION BETWEEN DETERGENT MICELLES AND MODEL PEPTIDE ANTIBIOTICS BY VARYING THE PEPTIDE CHARGE DISTRIBUTION. John Weirich , Brianna Haight, Olivier Lequin, Lucie Khemtémourian, Ludovic Carlier, Adrienne Loh 2789-P os B oard B219 ISOMERIC MODEL ANTIBIOTIC PEPTIDES DIFFERING ONLY IN CHARGE PLACEMENT ADOPT DIFFERENT HELICAL CONFORMATIONS. Jayna Sharma, Riley Larson, Olivier Lequin, Lucie Khemtémourian, Ludovic Carlier, Kevin Larsen, Theodore Savage, Adrienne Loh 2790-P os B oard B220 ANISOTROPIC MEMBRANE CURVATURE SENSING BY ANTIBACTERIAL PEPTIDES. Jordi Gómez-Llobregat, Martin Lindén 2791-P os B oard B221 MEMBRANE INTERACTION OF AN ANTI-BACTERIAL AAPEPTIDE DEFINED BY EPR SPECTROSCOPY. Pavanjeet Kaur , Yaqiong Li, Jianfeng Cai, Likai Song 2792-P os B oard B222 ACTIVITY OF ANTIMICROBIAL PEPTIDE PROTEGRIN-1 IS TUNED BY MEMBRANE CHOLESTEROL CONTENT. J. Michael Henderson , Kathleen D. Cao, Zhiliang L. Gong, Gregory T. Tietjen, Charles T. R. Heffern, Daniel Kerr, Nishanth Iyengar, Indroneil Roy, Alan J. Waring, Mati Meron, Binhua Lin, Sushil Satija, Jaroslaw Majewski, Ka Yee C. Lee 2793-P os B oard B223 WHAT VESICLE LEAKAGE REVEALS ABOUT ANTIMICROBIAL ACTIVITY (AND WHAT IT DOESN’T). Sara Hovakeemian, Runhui Liu, Samuel H. Gellman, Heiko Heerklotz

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland