Biophysical Society 59th Annual Meeting Program Guide

2794-P os B oard B224 VIRUS-MIMICKING POLYMER MOLECULAR BRUSHES ARE POTENT ANTIBIOTICS WITH DOUBLE SELECTIVITY. Yunjiang Jiang, Wan Zheng, Hairong Ma, Hongjun Liang 2795-P os B oard B225 ANALYSIS OF PISCIDIN AND LIPOPOLYSACCHARIDE INTERACTIONS: A STEP TOWARDS CHARACTERIZING IMMUNOMODULATION. Laura McCormick , Myriam Cotten 2796-P os B oard B226 STUDYING THE MECHANISMS OF HYBRID PEPTIDES CONTAINING PERMEABALIZING AND CELL PENETRATING DOMAINS. Maria A. LaBouyer , Donald E. Elmore 2797-P os B oard B227 BINDING OF DAPTOMYCIN TO LIPID BILAYERS IS NOT SIGNIFICANTLY ALTERED BY THE INCLUSION OF LYSYL- PHOSPHATIDYLGLYCEROL. Tala Khatib, Hannah Lineberry, Heather Stevenson, Bayer S. Arnold, Michael R. Yeaman, Antje Pokorny Proteins, Lipids, and Small Molecules (Boards B228-B243) 2798-P os B oard B228 PHOSPHATIDYLSERINE, A LIPID PRESENT AT THE OUTER MEMBRANE LEAFLET OF CANCER CELLS, HINDERS THE INSERTION OF PHLIP, A POTENTIAL CANCER CELL MARKER. Haden Scott 2799-P os B oard B229 UNDERSTANDING MOLECULAR COMPLEXITY IN PROTEIN AND PEPTIDE-LIPID SYSTEMS. Hannah M. Britt, Vian S. Ismail, Aruna S. Prakash, Jackie A. Mosely, John M. Sanderson 2800-P os B oard B230 PHLIP® TARGETING AND DELIVERY OF PNA TO SILENCE MICRORNA IN TUMOR CELLS§. Donald M. Engelman , Christopher J. Cheng, Raman Bahal, Imran A. Babar, Zachary Pincus, Francisco N. Barrera, Connie Liu, Alexander Svoronos, Demetrios T. Braddock, Peter M. Glazer, W Mark Saltzman, Frank J. Slack 2801-P os B oard B231 MEMBRANE CHOLESTEROL ASSOCIATION AND STRUCTURE OF TWO LEUKOTOXIN PEPTIDES. Cayla M. Miller , Angela C. Brown, Jeetain Mittal 2802-P os B oard B232 CHOLESTEROL ACCESSIBILITY SENSING BY PERFRINGOLYSIN O DERIVATIVES IS LINKED TO CHANGES IN THE SIZE OF THE OLIGOMER. Benjamin B. Jonhson, Robert J.C. Gilbert, Alejandro P. Heuck 2803-P os B oard B233 FREE ENERGIES FOR TRANS-MEMBRANE PORE FORMATION IN THE PRESENCE OF ARGININE-RICH PEPTIDES FROM MOLECULAR DYNAMICS SIMULATIONS. Neha Awasthi , Jochen S. Hub 2804-P os B oard B234 RESPONSE OF GWALP TRANSMEMBRANE PEPTIDES TO INCORPORATION OF BURIED HISTIDINE RESIDUES. Ashley N. Martfeld , Denise V. Greathouse, Roger E. Koeppe

2805-P os B oard B235 INFLUENCE OF CHOLESTEROL ON SINGLE ARGININE- CONTAINING TRANSMEMBRANE HELICAL PEPTIDES. Jordana K. Thibado , Ashley N. Martfeld, Denise V. Greathouse, Roger B oard B236 INFLUENCE OF A POTENTIALLY DESTABILIZING CENTRAL TRYPTOPHAN ON TRANSMEMBRANE HELIX DOMAINS. Vasu Suresh Kumar , Ashley N. Martfeld, Denise V. Greathouse, Roger E. Koeppe 2807-P os B oard B237 IONIZATION-DEPENDENT BEHAVIOR OF TRANSMEMBRANE HELICES THAT INCORPORATE GLU OR TYR RESIDUES. Venkatesan Rajagopalan , Denise V. Greathouse, Roger E. Koeppe 2808-P os B oard B238 DETECTION OF HELIX FRAYING IN DESIGNED TRANSMEMBRANE ALPHA HELICES. Armin Mortazavi , Venkatesan Rajagopalan, Denise V. Greathouse, Roger E. Koeppe 2809-P os B oard B239 COMPARING PEPTIDE-LIPID INTERACTIONS AND ANTIMICROBIAL ACTIVITIES OF PEPTIDES WITH SIMILAR “CORE” LENGTHS BUT VARIABLE ARGININE AND TRYPTOPHAN RESIDUES. Sara E. Whitlock , Roger E. Koeppe II, Denise A. Greathouse 2810-P os B oard B240 CHARACTERIZATION OF MAXIMIN 3 STRUCTURE AND MEMBRANE LEAKAGE. Brian Herbst, Jillian Glatz, Elizabeth Middleton 2811-P os B oard B241 CHARACTERIZATION OF MEMBRANE INTERACTIONS OF ANTIMICROBIAL LACTOFERRICIN PEPTIDES WITH CENTRAL RESIDUE SUBSTITUTIONS. Amanda Lowe , Denise V. Greathouse 2812-P os B oard B242 PROMOTION OF COALESCENCE IN BICELLAR MIXTURES BY AN SP-B FRAGMENT. Chris Miranda , Valerie Booth, Michael R. Morrow 2813-P os B oard B243 LIPID COMPOSITION INFLUENCES THE INSERTION AND FOLDING OF PHLIP PEPTIDES. Alexander G. Karabadzhak , Dhammika Weerakkody, Oleg A. Andreev, Yana K. Reshetnyak, Donald M. Engelman Protein-Lipid Interactions III (Boards B244-B269) 2814-P os B oard B244 international travel awardee ENHANCED HIV FUSION INHIBITORS EFFICACY REQUIRES MEMBRANE AFFINITY AND EXPOSURE OF THE POCKET BINDING DOMAIN OF C34 DERIVATIVES. Marcelo T. Augusto , Axel Hollmann, Miguel A. R. B. Castanho, Matteo Porotto, Antonello Pessi, Nuno C. Santos 2815-P os B oard B245 education travel awardee STRENGTH, NOT DEPTH: AN EXPLORATION OF DIFFERENTIAL MEMBRANE BINDING KINETICS OF SYNAPTOTAGMIN-1 AND SYNAPTOTAGMIN-7 C2 DOMAINS. Joshua V. Vermaas , Emad Tajkhorshid E. Koeppe 2806-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland