Biophysical Society 59th Annual Meeting Program Guide

659-P os B oard B439 MITOCHONDRIAL ABNORMALITIES IN A MOUSE CPVT MODEL WITH RYR2 LOSS-OF-FUNCTION MUTATION. V. Ramesh Iyer, Manuela Lavorato , Yang-Ting Zhao, Hector H. Valdivia, Clara Franzini - Armstrong 660-P os B oard B440 WNT SIGNALING SELECTIVELY INHIBITS SODIUM CHANNELS IN CARDIAC MYOCYTES. Wenbin Liang , Eduardo Marbán 661-P os B oard B441 THE PHYSIOLOGICAL RELEVANCE OF INTERACTIONS BETWEEN CMYBP-C AND ACTIN STUDIED IN A TRANSGENIC MOUSE MODEL. Sabine J. van Dijk , Kristina L. Bezold, Samantha P. Harris 662-P os B oard B442 THE HCM MUTATION L348P IN CMYBP-C ENHANCES THIN FILAMENT ACTIVATION THROUGH TROPOMYOSIN SHIFT. Ji Young Mun, Robert W. Kensler, Samantha P. Harris, Roger Craig 663-P os B oard B443 CROSSBRIDGE ARRANGEMENT IN CARDIAC THICK FILAMENTS ISOLATED FROM CMYBP-C PHOSPHOMIMETIC MICE. Robert W. Kensler , Roger Craig, Richard L. Moss 664-P os B oard B444 DECRYPTING THE STRUCTURAL, DYNAMIC AND ENERGETIC BASIS OF KINESIN INTERACTING WITH TUBULIN DIMER IN THREE ATPASE STATES BY ALL-ATOM MOLECULAR DYNAMICS SIMULATION. Wenjun Zheng , Srirupa Chakraborty 665-P os B oard B445 A NEW MECHANISM OF KINESIN MOLILITY: CONVERSION OF RANDOM MOTION TO DIRECTIONAL MOTION WITH RATCHET STRUCTURE. Ya-chang Chou 666-P os B oard B446 QUANTIFICATION OF IFT-DYNEIN DYNAMICS IN C.ELEGANS. Jona Mijalkovic , Bram Prevo, Felix Oswald, Pierre JJ Mangeol, Erwin JG Peterman 667-P os B oard B447 3D REAL-TIME ORBITAL TRACKING IN ZEBRAFISH EMBRYOS: HIGH SPATIOTEMPORAL ANALYSIS OF MITOCHONDRIAL DYNAMICS IN NEURONS. Fabian Wehnekamp , Gabriela Plucińska, Thomas Misgeld, Don C. Lamb 668-P os B oard B448 MOTOR COORDINATION IN LONG-DISTANCE TRANSPORT IN AXONS. Praveen Chowdary, Daphne Che, Bianxiao Cui 669-P os B oard B449 PHOSPHORYLATION REGULATES THE MOTILE PROPERTIES OF A MITOTIC KINESIN. Ofer Shapira , Larisa Gheber 670-P os B oard B450 cpow mid - career travel awardee MECHANO-CHEMICAL MODEL FOR THE STEPPING OF CYTOPLASMIC DYNEIN. Andreja Šarlah , Andrej Vilfan Kinesins, Dyneins, and Other Microtubule-based Motors (Boards B444-B471)

671-P os B oard B451 DYNACTIN FUNCTIONS AS BOTH A DYNAMIC TETHER AND BRAKE DURING DYNEIN-DRIVEN MOTILITY. Swathi Ayloo , Jacob E. Lazarus, Aditya Dodda, Mariko Tokito, E Michael Ostap, Erika B oard B452 TOWARDS SIMULATION OF VIRTUAL CELLS: THE KINESIN- MICROTUBULE MOLECULAR MOTOR. Srayanta Mukherjee , Jeffrey Skolnick 673-P os B oard B453 education travel awardee KINESIN-2’S ROLE IN INTRACELLULAR CARGO TRANSPORT: NAVIGATING THE COMPLEX MICROTUBULE LANDSCAPE. Gregory Hoeprich , William Hancock, Christopher Berger 674-P os B oard B454 COOPERATIVE TRANSPORT BY POPULATIONS OF FAST AND SLOW KINESINS UNCOVERS NOVEL FAMILY-DEPENDENT MOTOR CHARACTERISTICS IMPORTANT FOR IN VIVO FUNCTION. Göker Arpağ, Shankar Shastry, William O. Hancock, Erkan Tüzel 675-P os B oard B455 KINESIN REGULATION DYNAMICS THROUGH CARGO DELIVERY, A SINGLE MOLECULE INVESTIGATION. Anthony P. I. Kovacs , Jonathan M. Kessler, Huawen Lin, Susan K. Dutcher, Yan Mei Wang 676-P os B oard B456 SENSITIVITY OF MULTIPLE-KINESIN TRANSPORT TO MICROTUBULE LATTICE DEFECTS. K M Rifat Faysal, Stephen J. King, Jing Xu 677-P os B oard B457 CHARACTERIZING THE ALLOSTERIC EFFECT OF NUCLEOTIDE AND INHIBITOR BINDING TO THE KINESIN MOTOR DOMAIN. Guido Scarabelli , Barry J. Grant 678-P os B oard B458 EFFECT OF FORCE AND DISCRETE STEP-SIZE ON THE VELOCITY DISTRIBUTION OF PROCESSIVE MOLECULAR MOTORS. Huong T. Vu , Shaon Chakrabarti, Michael Hinczewski, D. Thirumalai 679-P os B oard B459 DEVELOPMENT OF PHOTO-CONTROLLED MOLECULAR SHUTTLE UTILIZING ATP DRIVEN MOTOR KINESIN. Naozumi Numata , Kazunori Kondo, Shinsaku Maruta 680-P os B oard B460 STUDY OF PHOSPHO-REGULATION OF A MITOTIC KINESIN USING A DIRECTED EVOLUTION APPROACH. Alina Goldstein , Nurit Siegler, Liam Holt, Leah Gheber 681-P os B oard B461 TRANSPORT BY A KINESIN IN THE PRESENCE OF MAGNETIC NANOPARTICLES. Ehsan Mirzakhalili , Eleni Gourgou, Bogdan B oard B462 KINETIC CHARACTERIZATION OF RICE PLANT SPECIFIC KINESIN E11 USING FLUORESCENT ATP ANALOGUE. Hironobu Taniguchi , Nozomi Umezu, Shinsaku Maruta Holzbaur 672-P os Epureanu 682-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland