Biophysical Society 60th Annual Meeting

1341-Pos Board B318 L-TYPE CALCIUM AND NCX CURRENTS DURING ISCHEMIA AND REPER- FUSION IN INTACT MOUSE HEARTS. Yuriana Aguilar-Sanchez, Myrian Zavalza, Victoria To, Alicia R. Mattiazzi, Josefina Ramos-Franco , Ariel L. Escobar 1342-Pos Board B319 DOWN REGULATION OF L-TYPE CALCIUM CURRENT IN RAT ATRIAL MYO- CYTES DURING HEART FAILURE. Andrew F. James , Richard C. Bond, Simon M. Bryant, Judy J. Watson, Jules C. Hancox, Clive H. Orchard 1343-Pos Board B320 ROSCOVITINE AS THE ARCHETYPAL MEMBER OF A NOVEL CLASS OF ANTI- ARRHYTHMICS TARGETING LATE I CA,L . Marina Angelini , Arash Pezhouman, Nicoletta Savalli, Antonios Pantazis, Araz Melkonian, James N. Weiss, Hrayr S. Karagueuzian, Riccardo Olcese 1344-Pos Board B321 TRANSIENT OUTWARD POTASSIUM CURRENT AND ITS ARRHYTHMOGEN- IC DYNAMICS IN CARDIAC MYOCYTES.  Julian W. Landaw , Alan Garfinkel, James N. Weiss, Zhilin Qu 1345-Pos Board B322 AN INVESTIGATION ON ELECTRICAL ACTIVITY AND SARCOLEMMAL K + CHANNELS IN CARDIOMYOCYTES FROM INSULIN-RESISTANT RAT HEART. Aysegul Toy , YUSUF OLGAR, Sinan Degirmenci, Erkan Tuncay, BELMA TURAN 1346-Pos Board B323 BOTH HYPERGLYCEMIA AND HYPERINSULINEMIA INDUCE CHANGES IN VOLTAGE-DEPENDENT K + CHANNEL CURRENTS IN H9C2 VENTRICULAR CELLS. Sinan Degirmenci , Yusuf Olgar, Ayesgul Toy, Belman Turan 1347-Pos Board B324 EDUCATION TRAVEL AWARDEE CAMKII INHIBITOR KN-93 DIRECTLY BLOCKS IKR IN CARDIAC MYO- CYTES. Bence Hegyi , Ye Chen-Izu, Zhong Jian, Rafael Shimkunas, Leighton T. Izu, Tamas Banyasz 1348-Pos Board B325 MODULATION OF HERG 1A TRAFFICKING BY HERG 1B SUBUNITS IN HEART. Kelly A. Aromolaran, Donald D. Chang, R. Suzanne Zukin, Henry M. Colecraft, Mohamed Chahine, Mohamed Boutjdir, Ademuyiwa Aromolaran 1349-Pos Board B326 BLOCKADE OF CALCIUM/CALMODULIN-DEPENDENT KINASE II (CAMKII) INDUCES HETEROGENEOUS DEPRESSION OF CONDUCTION AND PRO- MOTES ISCHEMIC VENTRICULAR FIBRILLATION (VF). Mark Warren , Katie J. Sciuto, Junko Shibayama, Alexey V. Zaitsev 1350-Pos Board B327 CONCURRENT PDE3 AND PDE4 ACTIVATION SUPPRESSES LOCAL CA 2+ RELEASES (LCR) TO REGULATE NORMAL SPONTANEOUS FIRING OF SINOATRIAL NODE CELLS (SANC). Tatiana M. Vinogradova , Yevgeniya Lukyanenko, Kirill V. Tarasov, Syevda Sirenko, Alexey E. Lyashkov, Yue Li, Edward G. Lakatta 1351-Pos Board B328 HETEROGENEITY IN BEATING AND RESPONSE TO BETA ADRENERGIC RECEPTOR STIMULATION IN ISOLATED SINGLE SINOATRIAL NODAL CELLS (SANC). Kenta Tsutsui , Oliver J. Monfredi, Ashley N. Wirth, Mary S. Kim, Rostislav Bychkov, Victor A. Maltsev, Edward G. Lakatta 1352-Pos Board B329 SMALL-CONDUCTANCE CA 2+ -ACTIVATED K + CURRENT IN ATRIAL FIBRILLA- TION: BOTH FRIEND AND FOE. Stefano Morotti , Jussi T. Koivumäki, Mary M. Maleckar, Nipavan Chiamvimonvat, Eleonora Grandi

1353-Pos Board B330 ARRHYTHMIA TRIGGERS IN 1D STRANDS OF VENTRICULAR MYO- CYTES. Shankar Iyer , Minu Madhvani, Brian Nguyen, Nicole Nguyen, Beshoy Iskander, Jie Li, Thao P. Nguyen 1354-Pos Board B331 ATRIAL EARLY AFTERDEPOLARIZATION: AN EMERGING PROPERTY OF THE FIBROTIC ATRIA? Neha Singh , Binh Nguyen, Himani Madnawat, Mojdeh Dooraghi, Shankar Iyer, Thao P. Nguyen 1355-Pos Board B332 DOWN REGULATION OF ATRIAL GAP JUNCTION IN METABOLIC SYN- DROME IS ASSOCIATED WITH VLDL-INDUCED O-LINKED GLYCOSYL- ATION. Hsiang-Chun Lee , Hsin-Ting Lin, Yi-Lin Hsiao, Sheng-Hsiung Sheu, Chu-Huang Chen, Wen-Ter Lai, Bin-Nan Wu 1356-Pos Board B333 VENTRICULAR MYOCYTES ELECTRICALLY COUPLE WITH NONMYOCYTES IN THE INFARCTED MOUSE HEART. Michael Rubart , Wen Tao, Xiao-long Lu, Shien-Fong Lin, Mark Soonpaa 1357-Pos Board B334 EPHAPTIC SELF-ATTENUATION CONCEALS EARLY AFTERDEPOLARIZATIONS ASSOCIATED WITH LONG QT-3 SYNDROME. Steven Poelzing, Amara Greer-Short, Donald K. Jessup, Seth H. Weinberg 1358-Pos Board B335 A NOVEL TARGET FOR ANTIARRHYTHMIC THERAPY: ENHANCEMENT OF CARDIAC CONDUCTION BY IONIC MODULATION OF EPHAPTIC COU- PLING. Sharon George , Morten Nielsen, Steven Poelzing Muscle Regulation (Boards B336 - B339) 1359-Pos Board B336 MAGNESIUM INFLUX IN PRIMARY CULTURED VENTRICULAR MYOCYTES OF ADULT RATS. Michiko Tashiro , Hana Inoue, Shinobu Tai, Masato Konishi 1360-Pos Board B337 MICE WITH DOUBLE KNOCKOUT OF CALPONIN 1 AND CALPONIN 2 GENES DEMONSTRATE CONTRACTILITY MODIFICATIONS IN VASCULAR SMOOTH MUSCLE. Han-Zhong Feng , Katsuhito Takahashi, Jian-Ping Jing 1361-Pos Board B338 BIOCHEMICAL COMPARISON OF RABBIT SKELETAL MUSCLE ALPHA AND BETA TROPOMYOSIN ISOFORMS. David H. Heeley , Elke M. Lohmeier- Vogel 1362-Pos Board B339 CONSEQUENCES OF REDUCED TROPONIN-C CALCIUM BINDING AFFINITY ON SLOW SKELETAL MUSCLE. Peter J. Reiser , Natalya Belevych, Svetlana Tikunova Voltage-gated K Channels, Mechanisms of Voltage Sensing and Gating II (Boards B340 - B369) 1363-Pos Board B340 CHARACTERIZATION OF THE σ-PORE IN MUTANT HKV1.3 POTASSIUM CHANNELS. Pavel Yurievitch Tyutyaev , Stephan Grissmer 1364-Pos Board B341 A NEAR-IR FLUORESCENT SENSOR FOR DETECTING CELLULAR POTASSIUM EFFLUX. Dhammika Bandara , Zhengmao Hua, Steven Pauff, Stephen Miller, Elizabeth Colby Davie, William Kobertz

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